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Aliases for RNF113A Gene

Aliases for RNF113A Gene

  • Ring Finger Protein 113A 2 3
  • Zinc Finger Protein 183 (RING Finger, C3HC4 Type) 2 3
  • ZNF183 3 4
  • RNF113 3 4
  • Zinc Finger Protein 183 4
  • Cwc24 3

External Ids for RNF113A Gene

Previous HGNC Symbols for RNF113A Gene

  • ZNF183

Previous GeneCards Identifiers for RNF113A Gene

  • GC0XM118787
  • GC0XM118888
  • GC0XM119004
  • GC0XM108497

Summaries for RNF113A Gene

Entrez Gene Summary for RNF113A Gene

  • This intronless gene encodes a protein which contains a C3H1-type zinc finger domain and a C3HC4 Ring-type (Really Interesting New Gene-type) zinc finger domain. The Ring-type zinc finger domain is identified in various tumor suppressors, DNA repair genes and cytokine receptor-associated molecules, and is probably involved in mediating protein-protein interactions. [provided by RefSeq, May 2010]

GeneCards Summary for RNF113A Gene

RNF113A (Ring Finger Protein 113A) is a Protein Coding gene. An important paralog of this gene is RNF113B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF113A Gene

Genomics for RNF113A Gene

Regulatory Elements for RNF113A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RNF113A Gene

Start:
119,870,475 bp from pter
End:
119,871,828 bp from pter
Size:
1,354 bases
Orientation:
Minus strand

Genomic View for RNF113A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNF113A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF113A Gene

Proteins for RNF113A Gene

  • Protein details for RNF113A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15541-R113A_HUMAN
    Recommended name:
    RING finger protein 113A
    Protein Accession:
    O15541
    Secondary Accessions:
    • B2RBR7

    Protein attributes for RNF113A Gene

    Size:
    343 amino acids
    Molecular mass:
    38787 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNF113A Gene

Proteomics data for RNF113A Gene at MOPED

Post-translational modifications for RNF113A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF113A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF113A Gene

Domains for RNF113A Gene

Gene Families for RNF113A Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers

Protein Domains for RNF113A Gene

Suggested Antigen Peptide Sequences for RNF113A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O15541

UniProtKB/Swiss-Prot:

R113A_HUMAN :
  • O15541
Similarity:
  • Contains 1 C3H1-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RNF113A: view

Function for RNF113A Gene

Gene Ontology (GO) - Molecular Function for RNF113A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 22365833
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with RNF113A: view

Phenotypes for RNF113A Gene

GenomeRNAi human phenotypes for RNF113A:
genes like me logo Genes that share phenotypes with RNF113A: view

Animal Model Products

CRISPR Products

miRNA for RNF113A Gene

miRTarBase miRNAs that target RNF113A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RNF113A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RNF113A Gene

Localization for RNF113A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RNF113A Gene COMPARTMENTS Subcellular localization image for RNF113A gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RNF113A Gene

Pathways for RNF113A Gene

SuperPathways for RNF113A Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for RNF113A Gene

None

No data available for Pathways by source for RNF113A Gene

Transcripts for RNF113A Gene

mRNA/cDNA for RNF113A Gene

(7) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNF113A Gene

Ring finger protein 113A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RNF113A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNF113A Gene

No ASD Table

Relevant External Links for RNF113A Gene

GeneLoc Exon Structure for
RNF113A
ECgene alternative splicing isoforms for
RNF113A

Expression for RNF113A Gene

mRNA expression in normal human tissues for RNF113A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RNF113A Gene

SOURCE GeneReport for Unigene cluster for RNF113A Gene Hs.458365

mRNA Expression by UniProt/SwissProt for RNF113A Gene

O15541-R113A_HUMAN
Tissue specificity: Ubiquitous
genes like me logo Genes that share expressions with RNF113A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for RNF113A Gene

Orthologs for RNF113A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RNF113A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RNF113A 35
  • 99.9 (n)
  • 99.71 (a)
RNF113A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 83 (a)
OneToMany
RNF113A 35
  • 91.16 (n)
  • 92.13 (a)
RNF113A 36
  • 92 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 77 (a)
OneToMany
-- 36
  • 94 (a)
OneToMany
RNF113A 35
  • 91.84 (n)
  • 94.46 (a)
mouse
(Mus musculus)
Mammalia Rnf113a1 16
Rnf113a1 36
  • 88 (a)
OneToOne
Rnf113a2 35
  • 85.07 (n)
  • 91.34 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 75 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Rnf113a2 35
  • 85.57 (n)
  • 90.75 (a)
chicken
(Gallus gallus)
Aves RNF113A 36
  • 77 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 77 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii rnf113a 36
  • 72 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG4973 36
  • 52 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea rnf-113 36
  • 38 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CWC24 36
  • 33 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8018 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 61 (a)
OneToMany
Species with no ortholog for RNF113A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RNF113A Gene

ENSEMBL:
Gene Tree for RNF113A (if available)
TreeFam:
Gene Tree for RNF113A (if available)

Paralogs for RNF113A Gene

Paralogs for RNF113A Gene

Selected SIMAP similar genes for RNF113A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RNF113A: view

Variants for RNF113A Gene

Structural Variations from Database of Genomic Variants (DGV) for RNF113A Gene

Variant ID Type Subtype PubMed ID
dgv2468e1 CNV Complex 17122850
dgv2469e1 CNV Complex 17122850
nsv7057 CNV Insertion 18451855

Relevant External Links for RNF113A Gene

HapMap Linkage Disequilibrium report
RNF113A
Locus Specific Mutation Databases (LSDB)
RNF113A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for RNF113A Gene

Disorders for RNF113A Gene

No disorders were found for RNF113A Gene.

No data available for UniProtKB/Swiss-Prot for RNF113A Gene

Publications for RNF113A Gene

  1. Identification of a new member (ZNF183) of the Ring finger gene family in Xq24-25. (PMID: 9224902) Frattini A. … Vezzoni P. (Gene 1997) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  5. A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PMID: 19690564) van Wijk S.J. … Timmers H.T. (Mol. Syst. Biol. 2009) 3

Products for RNF113A Gene

Sources for RNF113A Gene

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