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Aliases for RNF103-CHMP3 Gene

Aliases for RNF103-CHMP3 Gene

  • RNF103-CHMP3 Readthrough 2 3 5
  • RNF103-VPS24 Readthrough 2 3
  • RNF103-CHMP3 Read-Through 3
  • RNF103-VPS24 3

External Ids for RNF103-CHMP3 Gene

Previous HGNC Symbols for RNF103-CHMP3 Gene

  • RNF103-VPS24

Previous GeneCards Identifiers for RNF103-CHMP3 Gene

  • GC02M086738

Summaries for RNF103-CHMP3 Gene

Entrez Gene Summary for RNF103-CHMP3 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RNF103 (ring finger protein 103) and CHMP3 (charged multivesicular body protein 3) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Oct 2011]

GeneCards Summary for RNF103-CHMP3 Gene

RNF103-CHMP3 (RNF103-CHMP3 Readthrough) is a Protein Coding gene. Among its related pathways are Internalization of ErbB1 and Endocytosis. An important paralog of this gene is CHMP3.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF103-CHMP3 Gene

Genomics for RNF103-CHMP3 Gene

Regulatory Elements for RNF103-CHMP3 Gene

Enhancers for RNF103-CHMP3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RNF103-CHMP3 on UCSC Golden Path with GeneCards custom track

Promoters for RNF103-CHMP3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RNF103-CHMP3 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNF103-CHMP3 Gene

86,503,430 bp from pter
86,721,122 bp from pter
217,693 bases
Minus strand

Genomic View for RNF103-CHMP3 Gene

Genes around RNF103-CHMP3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF103-CHMP3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF103-CHMP3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF103-CHMP3 Gene

Proteins for RNF103-CHMP3 Gene

Post-translational modifications for RNF103-CHMP3 Gene

No Post-translational modifications

Other Protein References for RNF103-CHMP3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF103-CHMP3 Gene

Domains & Families for RNF103-CHMP3 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNF103-CHMP3 Gene

Function for RNF103-CHMP3 Gene

Phenotypes for RNF103-CHMP3 Gene

GenomeRNAi human phenotypes for RNF103-CHMP3:
genes like me logo Genes that share phenotypes with RNF103-CHMP3: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RNF103-CHMP3 Gene

Localization for RNF103-CHMP3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNF103-CHMP3 Gene

Pathways & Interactions for RNF103-CHMP3 Gene

SuperPathways for RNF103-CHMP3 Gene

genes like me logo Genes that share pathways with RNF103-CHMP3: view

Pathways by source for RNF103-CHMP3 Gene

1 BioSystems pathway for RNF103-CHMP3 Gene
1 KEGG pathway for RNF103-CHMP3 Gene

Gene Ontology (GO) - Biological Process for RNF103-CHMP3 Gene


No data available for SIGNOR curated interactions for RNF103-CHMP3 Gene

Drugs & Compounds for RNF103-CHMP3 Gene

No Compound Related Data Available

Transcripts for RNF103-CHMP3 Gene

mRNA/cDNA for RNF103-CHMP3 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNF103-CHMP3 Gene

No ASD Table

Relevant External Links for RNF103-CHMP3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNF103-CHMP3 Gene

mRNA expression in normal human tissues for RNF103-CHMP3 Gene

genes like me logo Genes that share expression patterns with RNF103-CHMP3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RNF103-CHMP3 Gene

Orthologs for RNF103-CHMP3 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RNF103-CHMP3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 71 (a)
(Canis familiaris)
Mammalia -- 36
  • 70 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 87 (a)
(Mus musculus)
Mammalia Chmp3 36
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 82 (a)
(Pan troglodytes)
Mammalia -- 36
  • 100 (a)
(Gallus gallus)
Aves -- 36
  • 87 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 68 (a)
(Danio rerio)
Actinopterygii chmp3 36
  • 79 (a)
fruit fly
(Drosophila melanogaster)
Insecta vps24 36
  • 57 (a)
(Caenorhabditis elegans)
Secernentea vps-24 36
  • 55 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes VPS24 36
  • 28 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 52 (a)
Species with no ortholog for RNF103-CHMP3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RNF103-CHMP3 Gene

Gene Tree for RNF103-CHMP3 (if available)
Gene Tree for RNF103-CHMP3 (if available)

Paralogs for RNF103-CHMP3 Gene

Paralogs for RNF103-CHMP3 Gene

genes like me logo Genes that share paralogs with RNF103-CHMP3: view

Variants for RNF103-CHMP3 Gene

Sequence variations from dbSNP and Humsavar for RNF103-CHMP3 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs383192 -- 86,626,343(+) AAAAA(A/C)AACAA intron-variant
rs433655 -- 86,626,406(+) TTAGC(A/G)GCAGC intron-variant
rs756151 -- 86,690,459(+) gtaca(A/G)agtac intron-variant
rs764062 -- 86,651,075(-) AAACT(C/T)TGATA intron-variant
rs1629293 -- 86,626,675(+) GAGTG(C/T)GCAAA intron-variant

Variation tolerance for RNF103-CHMP3 Gene

Residual Variation Intolerance Score: 31.3% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for RNF103-CHMP3 Gene

Disorders for RNF103-CHMP3 Gene

Relevant External Links for RNF103-CHMP3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNF103-CHMP3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF103-CHMP3 Gene

Publications for RNF103-CHMP3 Gene

  1. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 67
  2. Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. (PMID: 24159190) SeppAolAo I. … LehtimAoki T. (Eur. Heart J. 2014) 3
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3

Products for RNF103-CHMP3 Gene

Sources for RNF103-CHMP3 Gene