Aliases for RND2 Gene
External Ids for RND2 Gene
Previous HGNC Symbols for RND2 Gene
Previous GeneCards Identifiers for RND2 Gene
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]
GeneCards Summary for RND2 Gene
RND2 (Rho Family GTPase 2) is a Protein Coding gene. Among its related pathways are ERK Signaling and Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include GTP binding and protein N-terminus binding. An important paralog of this gene is RHOA.
UniProtKB/Swiss-Prot for RND2 Gene
May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity).