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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RND1 Gene

protein-coding GIFtS: 63
GCID: GC12M049250

Rho family GTPase 1

Explore 8 diseases affiliated with
RND1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Rho Family GTPase 1¹ ² ³		GTP-Binding Protein²
ARHS¹ ²		Ras Homolog Gene Family, Member S²
RHOS¹ ²		Rho-Related GTP-Binding Protein Rho6²
RHO6² ³		Rnd1³
Rho6¹

External Ids:	HGNC: 18314¹	Entrez Gene: 27289²	Ensembl: ENSG00000172602⁷	OMIM: 609038⁵	UniProtKB: Q92730³

Export aliases for RND1 gene to outside databases

Previous GC identifers: GC12M047537 GC12M046283

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RND1:

Members of the Rho GTPase family, such as RND1, regulate the organization of the actin cytoskeleton in response to

extracellular growth factors (Nobes et al., 1998 (PubMed 9531558)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: RND1_HUMAN, Q92730

Function: Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls

rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption

of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of

the cortical actin filaments

Gene Wiki entry for RND1 (Rnd1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_029419.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RND1 gene promoter:
NF-YA Egr-4 NF-YB POU2F1 CBF-A CBF-B POU2F1a CP1A NF-Y CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RND1 promoter sequence

Search SABiosciences Chromatin IP Primers for RND1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RND1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q12 Ensembl cytogenetic band: 12q13.12 HGNC cytogenetic band: 12q12

RND1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RND1 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M049250: view genomic region (about GC identifiers)

Start:	49,250,916 bp from pter	End:	49,259,681 bp from pter
Size:	8,766 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RND1_HUMAN, Q92730 (See protein sequence)

Recommended Name: Rho-related GTP-binding protein Rho6 precursor

Size: 232 amino acids; 26056 Da

Subunit: Binds GRB7 and PLXNB1. Interacts with UBXD5. Interacts with PLXNA2

Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton

3 PDB 3D structures from and Proteopedia for RND1:

2CLS (3D)

2REX (3D)

3Q3J (3D)

Secondary accessions: A8K9P7

Explore the universe of human proteins at neXtProt for RND1: NX_Q92730

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q92730

RND1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055285.1

ENSEMBL proteins:

ENSP00000447059 ENSP00000308461 ENSP00000449045

Reactome Protein details: Q92730
Human Recombinant Protein Products:

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	Novus Biologicals RND1 Proteins Novus Biologicals RND1 Lysates
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for RND1
	Uscn Proteins for RND1

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	TAS	--
GO:0005856	cytoskeleton	IEA	--
GO:0005886	plasma membrane	IEA	--
GO:0005912	adherens junction	IDA	9531558

RND1 for ontologies About GeneDecksing

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	ThermoFisher Antibodies for RND1

Assay Products for RND1:

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	GenScript Custom Assay Services for RND1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RND1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RND1 for domains About GeneDecksing

3 InterPro domains/families:

IPR003578 Small_GTPase_Rho

IPR005225 Small_GTP-bd_dom

IPR001806 Small_GTPase

Graphical View of Domain Structure for InterPro Entry Q92730

ProtoNet protein and cluster: Q92730

2 Blocks protein families:

IPB001806 Transforming protein P21 RAS signature

IPB003578 Ras small GTPase

UniProtKB/Swiss-Prot: RND1_HUMAN, Q92730

Similarity: Belongs to the small GTPase superfamily. Rho family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RND1_HUMAN, Q92730

Function: Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls

rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption

of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of

the cortical actin filaments

miRNA Products:		OriGene 3'-UTR Clone: RND1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RND1
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate RND1:
		hsa-miR-199a-5p hsa-miR-199b-5p
		SwitchGear 3'UTR luciferase reporter plasmid: RND1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RND1 (see all 7) OriGene shRNA RFP: RND1 OriGene siRNA: RND1
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for RND1

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		GenScript: all cDNA clones in your preferred vector: RND1 (NM_014470)
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		Search LifeMap BioReagents cell lines for RND1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RND1

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003924	GTPase activity	NAS	11095956
GO:0005102	receptor binding	IPI	19843518
GO:0005515	protein binding	IPI	10664463
GO:0005525	GTP binding	IEA	--

RND1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Sema4D in semaphorin signaling

	Sema4D in semaphorin signaling	1.00			Semaphorin interactions	0.44
	Sema4D induced cell migration and growth-cone collapse	0.83

Axon guidance

Axon guidance

1.00

Developmental Biology

0.69

Cell adhesion_Ephrins signaling

Cell adhesion Ephrins signaling

1.00

Cell adhesion_Ephrins signaling

1.00

Neurophysiological process Receptor-mediated axon growth repulsion

Neurophysiological process Receptor-mediated axon growth repulsion

1.00

Neurophysiological process_Receptor-mediated axon growth repulsion

0.94

SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion

SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

2 EMD Millipore Pathways for RND1

	Neurophysiological process Receptor-mediated axon growth repulsion
	Cell adhesion Ephrins signaling

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for RND1

Semaphorin Signaling

2 GeneGo (Thomson Reuters) Pathways for RND1

	Neurophysiological process Receptor-mediated axon growth repulsion
	Cell adhesion Ephrins signaling

5/7 Reactome Pathways for RND1 (see all 7)

	Developmental Biology
	Sema4D induced cell migration and growth-cone collapse
	Semaphorin interactions
	Sema4D in semaphorin signaling
	Sema4D mediated inhibition of cell attachment and migration

1 Kegg Pathway (Kegg details for RND1):

Axon guidance

RND1 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for RND1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/33 Interacting proteins for RND1 (Q92730^{1, 2, 3} ENSP00000308461⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 33)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PLXNB1	O43157²^,³, ENSP00000296440⁴	MINT-16324 MINT-16325 I2D: score=6 STRING: ENSP00000296440
GRB7	Q14451¹^,³, ENSP00000310771⁴	EBI-448618,EBI-1257061 I2D: score=4 STRING: ENSP00000310771
FRS2	Q8WU20³, ENSP00000299293⁴	I2D: score=1 STRING: ENSP00000299293
ID3	Q02535³, ENSP00000363689⁴	I2D: score=1 STRING: ENSP00000363689
PDE6D	O43924³, ENSP00000287600⁴	I2D: score=4 STRING: ENSP00000287600

About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006184	GTP catabolic process	NAS	9531558
GO:0007015	actin filament organization	IDA	9531558
GO:0007162	negative regulation of cell adhesion	IDA	9531558
GO:0007264	small GTPase mediated signal transduction	IEA	--
GO:0007411	axon guidance	TAS	--

RND1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

RND1 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RND1

1 HMDB Compound for RND1 About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

2 Novoseek chemical compound relationships for RND1 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
gdp	55.3	2	16042565 (1), 9531558 (1)
gtp	49.3	3	16042565 (1), 10664463 (1)

Search CenterWatch for drugs/clinical trials and news about RND1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RND1 gene:

NM_014470.3

Unigene Cluster for RND1:

Rho family GTPase 1

Hs.124940 [show with all ESTs]

Unigene Representative Sequence: AK124288

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000550607 ENST00000309739(uc001rsn.3) ENST00000548445 ENST00000553260

ENST00000551243

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RND1
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate RND1:
		hsa-miR-199a-5p hsa-miR-199b-5p
		SwitchGear 3'UTR luciferase reporter plasmid: RND1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RND1

Additional cDNA sequence:

AB040147.1 AF498967.1 AK124288.1 AK292762.1 AL359573.1 BC026356.1 Y07923.1

6 DOTS entries:

DT.105252 DT.95219010 DT.101956016 DT.121180519 DT.121180515 DT.91758283

10 AceView cDNA sequences:

BC026356 AL359573 CR604397 CR621792 AF498967 CR602286 NM_014470 Y07923

AK124288 AB040147

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for RND1 About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b
SP1:					-				-
SP2:									-
SP3:

ECgene alternative splicing isoforms for RND1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RND1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTCTCACCT

About this image

RND1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RND1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RND1

SOURCE GeneReport for Unigene cluster: Hs.124940

UniProtKB/Swiss-Prot: RND1_HUMAN, Q92730

Tissue specificity: Mostly expressed in brain and liver

SABiosciences Expression via Pathway-Focused PCR Arrays including RND1:

Notch Signaling Targets in human mouse rat

Cardiotoxicity in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RND1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for RND1 gene from 3/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	RND1⁶	--	86(a)	1 ↔ 1	2(94290846-94295818)
African clawed frog (Xenopus laevis)	Amphibia	rho6-prov²	GTP-binding protein	78.25(n)		BC055983.1
zebrafish (Danio rerio)	Actinopterygii	rnd1l¹	Rho family GTPase 1 like	75.86(n) 82.76(a)		553414 NM_001044396.2 NP_001037861.1

ENSEMBL Gene Tree for RND1 (if available)
TreeFam Gene Tree for RND1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RND1 gene

RHOB² RHOD² RHOA² RHOF² RHOC² RND3²

18/21 SIMAP similar genes for RND1 using alignment to 3 protein entries: RND1_HUMAN (see all proteins) (see all similar genes):

RND3 ARHE RND2 RHOA RHOB RHOC

ARHA RHOD ARHG RAC2 RHOG RAC3

RHOJ RAC1 RHOF RHOU RHOV CDC42

RND1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2446974^1,2	C,F,A,	--	49250860(-)	`cttttT/Attttt`	1	--	ds500¹		3		NA	124
rs189172287^1,2		--	49251007(+)	`ACACTC/GCCCCC`	1	--	ut3¹		0	--	--	--	--
rs78844933^1,2		--	49251172(+)	`GGACCC/GTGGGG`	1	--	ut3¹		2		CSA WA	120
rs73300177^1,2	C,	--	49251331(+)	`CTGCCG/ACTCCA`	1	--	ut3¹		2		WA	120
rs114688735^1,2	F,	--	49251351(+)	`TCTCCG/ATTGCT`	1	--	ut3¹		1		WA	118
rs192510977^1,2		--	49251369(+)	`TAGAGA/GGGAAG`	1	--	ut3¹		0	--	--	--	--
rs144384916^1,2	C,	--	49251522(+)	`GGAGC-/GGGGGG`	1	--	ut3¹		0	--	--	--	--
rs183946921^1,2		--	49251601(+)	`CGTCAA/GGTCCT`	1	--	ut3¹		0	--	--	--	--
rs144205522^1,2		--	49251713(+)	`CCTCCC/TTCTCC`	1	--	ut3¹		0	--	--	--	--
rs188129600^1,2	C,	--	49251740(+)	`CAAGGA/GAGGAA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RND1 (49250916 - 49259681 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RND1
1 CNV: 4777

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RND1

DNA2.0 Custom Variant and Variant Library Synthesis for RND1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RND1 for disorders           About GeneDecksing

OMIM gene information: 609038    OMIM disorders: --

8 diseases for RND1:    About MalaCards

hantavirus pulmonary syndrome alcoholic psychosis mood disorder alcoholism

t-cell leukemia leukemia retinitis neuronitis

1 disease from the University of Copenhagen DISEASES database for RND1:

Alcoholic psychosis

Export disorders for RND1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RND1 gene, integrated from 9 sources (see all 45):
(articles sorted by number of sources associating them with RND1)

Utopia: connect your pdf to the dynamic
world of online information

A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion. (PubMed id 9531558)^{1, 2, 3, 9} Nobes C.D.... Chardin P. (1998)
Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF- mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells. (PubMed id 12730235)^{1, 2, 9} Oinuma I.... Negishi M. (2003)
Rnd1, a novel rho family GTPase, induces the formation of neuritic processes in PC12 cells. (PubMed id 11095956)^{1, 2, 9} Aoki J.... Negishi M. (2000)
Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family. (PubMed id 10664463)^{1, 2, 9} Vayssiere B.... Camonis J. (2000)
Structure and function of the intracellular region of the plexin-b1 transmembrane receptor. (PubMed id 19843518)^{1, 2} Tong Y....Buck M. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers. (PubMed id 11940653)^{1, 2} Katoh H.... Negishi M. (2002)
Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells. (PubMed id 15738000)^{1, 9} Harada A....Negishi M. (2005)
Rnd1 regulates axon extension by enhancing the microtubule destabilizing activity of SCG10. (PubMed id 18996843)^{1, 9} Li Y.H....PA1schel A.W. (2009)
Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain. (PubMed id 17916560)^{1, 9} Tong Y....Buck M. (2007)

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Entrez Gene: 27289	HGNC: 18314	AceView: RND1	Ensembl:ENSG00000172602	euGenes: HUgn27289
ECgene: RND1	Kegg: 27289	H-InvDB: RND1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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