Aliases for RNASET2 Gene
External Ids for RNASET2 Gene
Previous GeneCards Identifiers for RNASET2 Gene
This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]
GeneCards Summary for RNASET2 Gene
RNASET2 (Ribonuclease T2) is a Protein Coding gene. Diseases associated with RNASET2 include Leukoencephalopathy, Cystic, Without Megalencephaly and Rnase T2-Deficient Leukoencephalopathy. Among its related pathways are Innate Immune System. GO annotations related to this gene include RNA binding and endoribonuclease activity. An important paralog of this gene is ENSG00000249141.
UniProtKB/Swiss-Prot for RNASET2 Gene
Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism.