Aliases for RNASET2 Gene
External Ids for RNASET2 Gene
Previous GeneCards Identifiers for RNASET2 Gene
This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]
GeneCards Summary for RNASET2 Gene
RNASET2 (Ribonuclease T2) is a Protein Coding gene. Diseases associated with RNASET2 include Leukoencephalopathy, Cystic, Without Megalencephaly and Rnase T2-Deficient Leukoencephalopathy. Among its related pathways are Immune System. GO annotations related to this gene include RNA binding and endoribonuclease activity. An important paralog of this gene is ENSG00000249141.
UniProtKB/Swiss-Prot for RNASET2 Gene
Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism.