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Aliases for RNASEK-C17orf49 Gene

Subcategory (RNA class) for RNASEK-C17orf49 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for RNASEK-C17orf49 Gene

  • RNASEK-C17orf49 Readthrough 2 3 5
  • RNASEK-C17orf49 Readthrough (Non-Protein Coding) 2

External Ids for RNASEK-C17orf49 Gene

Previous GeneCards Identifiers for RNASEK-C17orf49 Gene

  • GC17P006916
  • GC17P006919

Summaries for RNASEK-C17orf49 Gene

Entrez Gene Summary for RNASEK-C17orf49 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RNASEK (ribonuclease, RNase K) and C17orf49 (chromosome 17 open reading frame 49) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is unlikely to produce a protein product. [provided by RefSeq, Jan 2011]

GeneCards Summary for RNASEK-C17orf49 Gene

RNASEK-C17orf49 (RNASEK-C17orf49 Readthrough) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include chromatin binding. An important paralog of this gene is C17orf49.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNASEK-C17orf49 Gene

Genomics for RNASEK-C17orf49 Gene

Regulatory Elements for RNASEK-C17orf49 Gene

Enhancers for RNASEK-C17orf49 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around RNASEK-C17orf49 on UCSC Golden Path with GeneCards custom track

Promoters for RNASEK-C17orf49 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RNASEK-C17orf49 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNASEK-C17orf49 Gene

Chromosome:
17
Start:
7,012,417 bp from pter
End:
7,017,524 bp from pter
Size:
5,108 bases
Orientation:
Plus strand

Genomic View for RNASEK-C17orf49 Gene

Genes around RNASEK-C17orf49 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNASEK-C17orf49 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNASEK-C17orf49 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNASEK-C17orf49 Gene

Proteins for RNASEK-C17orf49 Gene

  • Protein details for RNASEK-C17orf49 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H0YIS7
    Recommended name:
    Protein RNASEK-C17orf49
    Protein Accession:
    H0YIS7

    Protein attributes for RNASEK-C17orf49 Gene

    Size:
    233 amino acids
    Molecular mass:
    24879 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNASEK-C17orf49 Gene

Protein Expression for RNASEK-C17orf49 Gene

Post-translational modifications for RNASEK-C17orf49 Gene

No Post-translational modifications

Other Protein References for RNASEK-C17orf49 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for RNASEK-C17orf49 Gene

Domains & Families for RNASEK-C17orf49 Gene

Protein Domains for RNASEK-C17orf49 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNASEK-C17orf49: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNASEK-C17orf49 Gene

Function for RNASEK-C17orf49 Gene

Phenotypes for RNASEK-C17orf49 Gene

GenomeRNAi human phenotypes for RNASEK-C17orf49:
genes like me logo Genes that share phenotypes with RNASEK-C17orf49: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNASEK-C17orf49 Gene

Localization for RNASEK-C17orf49 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RNASEK-C17orf49 Gene COMPARTMENTS Subcellular localization image for RNASEK-C17orf49 gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1

Gene Ontology (GO) - Cellular Components for RNASEK-C17orf49 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RNASEK-C17orf49: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RNASEK-C17orf49 Gene

Pathways & Interactions for RNASEK-C17orf49 Gene

SuperPathways for RNASEK-C17orf49 Gene

No Data Available

Interacting Proteins for RNASEK-C17orf49 Gene

Gene Ontology (GO) - Biological Process for RNASEK-C17orf49 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNASEK-C17orf49 Gene

Drugs & Compounds for RNASEK-C17orf49 Gene

No Compound Related Data Available

Transcripts for RNASEK-C17orf49 Gene

mRNA/cDNA for RNASEK-C17orf49 Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNASEK-C17orf49 Gene

No ASD Table

Relevant External Links for RNASEK-C17orf49 Gene

GeneLoc Exon Structure for
RNASEK-C17orf49
ECgene alternative splicing isoforms for
RNASEK-C17orf49

Expression for RNASEK-C17orf49 Gene

mRNA expression in normal human tissues for RNASEK-C17orf49 Gene

mRNA expression in normal human tissues for RNASEK-C17orf49 Gene

Protein differential expression in normal tissues from HIPED for RNASEK-C17orf49 Gene

This gene is overexpressed in Urine (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for RNASEK-C17orf49 Gene



Protein tissue co-expression partners for RNASEK-C17orf49 Gene

genes like me logo Genes that share expression patterns with RNASEK-C17orf49: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RNASEK-C17orf49 Gene

Orthologs for RNASEK-C17orf49 Gene

This gene was present in the common ancestor of animals.

Orthologs for RNASEK-C17orf49 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia BAP18 35
  • 93 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 92 (a)
OneToMany
mouse
(Mus musculus)
Mammalia 0610010K14Rik 35
  • 91 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 63 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii zgc:103508 35
  • 66 (a)
ManyToMany
zgc:92664 35
  • 63 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG33695 35
  • 22 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y43F8C.6 35
  • 11 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3343 35
  • 31 (a)
OneToMany
Species where no ortholog for RNASEK-C17orf49 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RNASEK-C17orf49 Gene

ENSEMBL:
Gene Tree for RNASEK-C17orf49 (if available)
TreeFam:
Gene Tree for RNASEK-C17orf49 (if available)

Paralogs for RNASEK-C17orf49 Gene

Paralogs for RNASEK-C17orf49 Gene

(3) SIMAP similar genes for RNASEK-C17orf49 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RNASEK-C17orf49: view

Variants for RNASEK-C17orf49 Gene

Structural Variations from Database of Genomic Variants (DGV) for RNASEK-C17orf49 Gene

Variant ID Type Subtype PubMed ID
esv2422288 CNV deletion 17116639
nsv457659 CNV loss 19166990
nsv574322 CNV loss 21841781
nsv952117 CNV deletion 24416366

Relevant External Links for RNASEK-C17orf49 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNASEK-C17orf49

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for RNASEK-C17orf49 Gene

Disorders for RNASEK-C17orf49 Gene

Relevant External Links for RNASEK-C17orf49

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RNASEK-C17orf49

No disorders were found for RNASEK-C17orf49 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNASEK-C17orf49 Gene

Publications for RNASEK-C17orf49 Gene

  1. An atlas of genetic influences on human blood metabolites. (PMID: 24816252) Shin S.Y. … Soranzo N. (Nat. Genet. 2014) 3 65
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 65

Products for RNASEK-C17orf49 Gene

Sources for RNASEK-C17orf49 Gene

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