Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RNASE11 Gene

protein-coding   GIFtS: 45
GCID: GC14M021051

Ribonuclease, RNase A Family, 11 (Non-Active)

(Previous name: chromosome 14 open reading frame 6)
(Previous symbol: C14orf6)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ribonuclease, RNase A Family, 11 (Non-Active)1 2     Probable Ribonuclease 112
C14orf61 2 3     Ribonuclease 112
RNase 112 3     EC 3.1.27.-3
Chromosome 14 Open Reading Frame 61     

External Ids:    HGNC: 192691   Entrez Gene: 1226512   Ensembl: ENSG000001734647   UniProtKB: Q8TAA13   

Export aliases for RNASE11 gene to outside databases

Previous GC identifers: GC14M020121 GC14M001172


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RNASE11 Gene: 
RNASE11 (ribonuclease, RNase A family, 11 (non-active)) is a protein-coding gene. Diseases associated with RNASE11 include pancreatitis. GO annotations related to this gene include pancreatic ribonuclease activity and nucleic acid binding.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RNASE11 gene promoter:
         ISGF-3   Pbx1a   Nkx2-2   XBP-1   C/EBPalpha   Gfi-1   RORalpha2   PPAR-alpha   Cart-1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRNASE11 promoter sequence
   Search SABiosciences Chromatin IP Primers for RNASE11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNASE11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.1

RNASE11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNASE11 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M021051:  view genomic region     (about GC identifiers)

Start:
21,051,051 bp from pter      End:
21,078,043 bp from pter
Size:
26,993 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RNS11_HUMAN, Q8TAA1 (See protein sequence)
Recommended Name: Probable ribonuclease 11 precursor  
Size: 199 amino acids; 22427 Da
Subcellular location: Secreted (Potential)

Explore the universe of human proteins at neXtProt for RNASE11: NX_Q8TAA1

Explore proteomics data for RNASE11 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TAA1

  • RNASE11 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RNASE11 Protein Expression
    REFSEQ proteins: NP_660293.1  
    ENSEMBL proteins: 
     ENSP00000338288   ENSP00000451318   ENSP00000451563   ENSP00000381093   ENSP00000381092  
     ENSP00000395210   ENSP00000401398   ENSP00000451839   ENSP00000452412   ENSP00000415954  
     ENSP00000451466  

    Human Recombinant Protein Products for RNASE11: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for RNASE11
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for RNASE11
    GenScript Custom Purified and Recombinant Proteins Services for RNASE11
    Novus Biologicals RNASE11 Protein
    Novus Biologicals RNASE11 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RNASE11 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    RNASE11 for ontologies           About GeneDecksing



    RNASE11 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RNASE11
    GenScript Custom Superior Antibodies Services for RNASE11
    Novus Biologicals RNASE11 Antibodies
    Abcam antibodies for RNASE11
    Cloud-Clone Corp. Antibodies for RNASE11 
    ThermoFisher Antibodies for RNASE11
    LSBio Antibodies in human, mouse, rat for RNASE11 

    Assay Products for RNASE11: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RNASE11
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RNASE11
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RNASE11 
    Cloud-Clone Corp. CLIAs for RNASE11


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNASE: Ribonucleases, RNase A

    2 InterPro protein domains:
     IPR023412 RNaseA_domain
     IPR001427 RNaseA

    Graphical View of Domain Structure for InterPro Entry Q8TAA1

    ProtoNet protein and cluster: Q8TAA1

    1 Blocks protein domain: IPB001427 Pancreatic ribonuclease

    UniProtKB/Swiss-Prot: RNS11_HUMAN, Q8TAA1
    Similarity: Belongs to the pancreatic ribonuclease family


    RNASE11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Enzyme Number (IUBMB): EC 3.1.27.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0004522pancreatic ribonuclease activity IEA--
         
    RNASE11 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RNASE11 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RNASE11

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RNASE11 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RNASE11 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNASE11
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate RNASE11:
    hsa-miR-1290 hsa-miR-483-3p
    SwitchGear 3'UTR luciferase reporter plasmidRNASE11 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RNASE11
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNASE11

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RNASE11
    Sirion Biotech Customized adenovirus for overexpression of RNASE11

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for RNASE11 (see all 7)
    OriGene ORF clones in mouse, rat for RNASE11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RNASE11 (NM_145250)
    Sino Biological Human cDNA Clone for RNASE11
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNASE11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNASE11
    Sirion Biotech Customized lentivirus for stable overexpression of RNASE11 
                         Customized lentivirus expression plasmids for stable overexpression of RNASE11 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RNASE11
    Search LifeMap BioReagents cell lines for RNASE11
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNASE11


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNASE11

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for RNASE11:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RNASE11 (RNS11)

    Search CenterWatch for drugs/clinical trials and news about RNASE11 / RNS11

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RNASE11 gene: 
    NM_145250.3  

    Unigene Cluster for RNASE11:

    Ribonuclease, RNase A family, 11 (non-active)
    Hs.112761  [show with all ESTs]
    Unigene Representative Sequence: NM_145250
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335950(uc010ahv.3 uc010ahx.3 uc010ahw.3 uc001vxs.3)
    ENST00000553849 ENST00000555841 ENST00000398009 ENST00000398008 ENST00000432835
    ENST00000443456 ENST00000557503 ENST00000557105 ENST00000413502 ENST00000554842

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNASE11
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate RNASE11:
    hsa-miR-1290 hsa-miR-483-3p
    SwitchGear 3'UTR luciferase reporter plasmidRNASE11 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RNASE11
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNASE11
    Clone
    Products:
         
    OriGene clones in human, mouse for RNASE11 (see all 7)
    OriGene ORF clones in mouse, rat for RNASE11
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RNASE11 (NM_145250)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNASE11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNASE11
    Sirion Biotech Customized lentivirus for stable overexpression of RNASE11 
                         Customized lentivirus expression plasmids for stable overexpression of RNASE11 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RNASE11
    OriGene qSTAR qPCR primer pairs in human, mouse for RNASE11
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RNASE11
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNASE11
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNASE11

    Additional mRNA sequence: 

    AK098687.1 AK292348.1 AK314065.1 AY358794.1 AY665806.1 BC025410.1 BX161458.1 

    6 DOTS entries:

    DT.404467  DT.303030  DT.100751196  DT.95069743  DT.95263792  DT.95338563 

    24/42 AceView cDNA sequences (see all 42):

    NM_145250 BX398183 AA609760 BP371081 BI831242 BX161458 BG722557 BC025410 
    AI809974 AW188146 BX102349 BI829613 AA382997 BX093877 BG717788 AK098687 
    BI459201 BX368092 AI478869 BI459952 AW274139 BI825312 BI461508 CB998266 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for RNASE11 (see all 9)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g
    SP1:        -     -     -     -     -     -     -     -     -           -                                             
    SP2:                    -     -     -     -     -     -     -           -                                             
    SP3:                                -     -     -     -     -           -                                             
    SP4:                                                        -           -                                             
    SP5:                                                  -     -           -                                             


    ECgene alternative splicing isoforms for RNASE11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RNASE11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGAATAGA
    RNASE11 Expression
    About this image


    See RNASE11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RNASE11

    SOURCE GeneReport for Unigene cluster: Hs.112761
        SABiosciences Custom PCR Arrays for RNASE11
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RNASE11
    OriGene qSTAR qPCR primer pairs in human, mouse for RNASE11
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RNASE11
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNASE11
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNASE11
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNASE11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for RNASE11 gene from 1/4 species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rnase111 , 5 ribonuclease, RNase A family, 11 (non-active)1, 5 68.97(n)1
    49.47(a)1
      14 (26.36 cM)5
    4971131  NM_001011877.11  NP_001011877.11 
     510494515 


    ENSEMBL Gene Tree for RNASE11 (if available)
    TreeFam Gene Tree for RNASE11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/170 SNPs in RNASE11 are shown (see all 170)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs12436021,2
    C,F,O,H--21050557(-) TTTCCT/GACAGT 1 -- ds500130Minor allele frequency- G:0.07NS EA NA WA CSA 2778
    rs1130222221,2
    C,F--21050601(+) GAGGAG/AACTGC 1 -- ds50012Minor allele frequency- A:0.03CSA WA 120
    rs740343371,2
    C,F--21050637(+) TCCACG/CCTTCT 1 -- ds50011Minor allele frequency- C:0.50WA 2
    rs762603501,2
    C,F--21050656(+) AGTGGG/TTGGTA 1 -- ds50011Minor allele frequency- T:0.05NA 120
    rs1918599761,2
    --21050776(+) GCATTA/TTGCTT 1 -- ds50010--------
    rs1506063581,2
    --21050900(+) TCAAAC/TGTACA 1 -- ds50010--------
    rs71417471,2
    C,F,A,H--21050921(+) TGTAAT/CGCTGC 1 -- ds500126Minor allele frequency- C:0.34NS EA NA WA CSA 2780
    rs71417651,2
    C,F,A,H--21050947(+) AAATGT/ATTTAC 1 -- ds500110Minor allele frequency- A:0.13NS EA NA CSA WA 738
    rs1396981181,2
    C--21050957(+) CAGTTA/C/GCAGTA 1 -- ds50010--------
    rs774209791,2
    C,F--21050998(+) GCTTCG/AGGAAA 1 -- ds50011Minor allele frequency- A:0.03WA 118

    HapMap Linkage Disequilibrium report for RNASE11 (21051051 - 21078043 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RNASE11:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv901469CNV Loss21882294
    nsv901468CNV Gain21882294
    esv23438CNV Gain+Loss19812545

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing RNASE11
    DNA2.0 Custom Variant and Variant Library Synthesis for RNASE11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for RNASE11:    About MalaCards
    pancreatitis    


    RNASE11 for disorders           About GeneDecksing


    Export disorders for RNASE11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RNASE11 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with RNASE11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    4. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    5. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    6. The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories. (PubMed id 15676279)1 Cho S.... Zhang J. (2005)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 122651 HGNC: 19269 AceView: C14orf6 Ensembl:ENSG00000173464 euGenes: HUgn122651
    ECgene: RNASE11 H-InvDB: RNASE11

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RNASE11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RNASE11 gene:
    Search GeneIP for patents involving RNASE11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     Browse Purified and Recombinant Proteins at EMD Millipore
     EMD Millipore small molecules (inhibitor) for RNASE11
     Browse Kits and Assays available from EMD Millipore
     Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
     Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
     Browse for Gene Knock-down Tools from EMD Millipore
     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for RNASE11  
     OriGene qPCR primer pairs and template standards for RNASE11   OriGene Protein Over-expression Lysate for RNASE11  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RNASE11  
     OriGene qSTAR qPCR primer pairs in human, mouse for RNASE11   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RNASE11   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RNASE11   OriGene Custom Protein Services for RNASE11  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNASE11
     QIAGEN SeqTarget long-range PCR primers for resequencing RNASE11
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNASE11
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNASE11
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNASE11
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNASE11
     GenScript Custom Purified and Recombinant Proteins Services for RNASE11 GenScript cDNA clones with any tag delivered in your preferred vector for RNASE11
     GenScript Custom Assay Services for RNASE11 GenScript Custom Superior Antibodies Services for RNASE11
     GenScript Custom overexpressing Cell Line Services for RNASE11 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RNASE11 promoter
     Search Chromatin IP Primers for RNASE11
     RT2 qPCR Primer Assay in human, mouse, rat RNASE11
     Search GNC Networks for RNASE11
     SABiosciences Custom PCR Arrays for RNASE11
     Search Tocris compounds for RNASE11 (RNS11)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for RNASE11
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RNASE11 antibodies
     RNASE11 proteins
     RNASE11 lysates
     Antibodies for RNASE11
     See all of Abcam's Antibodies, Kits and Proteins for RNASE11
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for RNASE11
     Antibodies for RNASE11
     ELISAs for RNASE11
     CLIAs for RNASE11
     Search LifeMap BioReagents cell lines for RNASE11
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNASE11
     SwitchGear 3'UTR luciferase reporter plasmids for RNASE11
     SwitchGear Promoter luciferase reporter plasmids for RNASE11
     ThermoFisher Antibodies for RNASE11
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNASE11
     inGenious Targeting Laboratory - Custom generated mouse model solutions for RNASE11
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RNASE11
    Customized:
     lentivirus for stable overexpression of RNASE11
     lentivirus expression plasmids for stable overexpression of RNASE11
     adenovirus for overexpression of RNASE11
     LSBio Antibodies in human, mouse, rat for RNASE11
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RNASE11 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4