Subcategory (RNA class) for RNA5SP478 Gene
Previous HGNC Symbols for RNA5SP478 Gene
GeneCards Summary for RNA5SP478 Gene
RNA5SP478 (RNA, 5S Ribosomal Pseudogene 478) is a Pseudogene, and is affiliated with the rRNA class.
fRNAdb sequence ontologies for RNA5SP478 Gene
5S ribosomal RNA: 5S ribosomal RNA (5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilises 5S rRNA until it is required for transcription.