Aliases for RN7SL744P Gene
Subcategory (RNA class) for RN7SL744P Gene
SRP
External Ids for RN7SL744P Gene
- HGNC: 46760
- Entrez Gene: 106479493
- Ensembl: ENSG00000264028
ORGUL Members for RN7SL744P Gene
Previous GeneCards Identifiers for RN7SL744P Gene
- GC12P054740
Summaries for RN7SL744P Gene
GeneCards Summary for RN7SL744P Gene
RN7SL744P (RNA, 7SL, Cytoplasmic 744, Pseudogene) is a Pseudogene, and is affiliated with the SRP RNA class.
fRNAdb sequence ontologies for RN7SL744P Gene
-
Metazoan signal recognition particle RNA: The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures, as represented by this family. Eight helical elements fold into the Alu and S domains, separated by a long linker region [1,2]. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP [1]. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition [2,3]. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54 binding [1]. The Signal Recognition Particle Database (SRPDB) [4] provides compilations of SRP components, with phylogenetic data and structural illustrations. Many sequences below the threshold for this family are clearly closely related, but are most likely to be SRP RNA derived pseudogenes. The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. While the threshold of this family is set high so as to minimise the number of hits to such regions, it is likely that some remain.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SL744P Gene
Genomics for RN7SL744P Gene
Regulatory Elements for RN7SL744P Gene
Enhancers for RN7SL744P Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH12G054350 | 1.8 | FANTOM5 Ensembl ENCODE dbSUPER | 0.4 | +7.7 | 7706 | 4.0 | HDGF PKNOX1 FOXA2 FEZF1 TCF12 ZNF121 GLIS2 ZNF263 SP3 YY2 | RNU6-950P COPZ1 ZNF385A CBX5 GPR84 PDE1B LOC102724050 RN7SL744P |
| GH12G054336 | 1.5 | Ensembl ENCODE dbSUPER | 0.4 | -6.4 | -6373 | 2.6 | ARNT SIN3A TCF12 GATA2 FOS NCOA1 REST SMARCB1 MEF2D MAFF | GPR84 RNU6-950P COPZ1 CBX5 GC12P054339 RN7SL744P |
| GH12G054340 | 0.7 | ENCODE | 0.7 | -2.9 | -2890 | 1.7 | SOX5 SOX13 RAD21 FOXA1 YY1 NR2F2 PRDM6 JUND ATF3 HNF4G | GPR84 RNU6-950P COPZ1 ZNF385A CBX5 GTSF1 RN7SL744P GC12P054339 |
| GH12G054348 | 0.6 | dbSUPER | 0.7 | +4.8 | 4845 | 1.4 | NFIC NFIB HMBOX1 FOS NFE2 EMSY | RNU6-950P COPZ1 CBX5 ZNF385A LOC102724050 RN7SL744P |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RN7SL744P on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for RN7SL744P Gene
- Chromosome:
- 12
- Start:
- 54,344,610 bp from pter
- End:
- 54,344,876 bp from pter
- Size:
- 267 bases
- Orientation:
- Plus strand
Genomic View for RN7SL744P Gene
Genes around RN7SL744P on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q13.13 by Ensembl
- 12q13.13 by Entrez Gene
- 12q13.13 by HGNC
RN7SL744P Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
No data available for RefSeq DNA sequence for RN7SL744P Gene
Proteins for RN7SL744P Gene
Post-translational modifications for RN7SL744P Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for RN7SL744P
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RN7SL744P
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Assay Products
No data available for DME Specific Peptides for RN7SL744P Gene
Domains & Families for RN7SL744P Gene
Gene Families for RN7SL744P Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SL744P Gene
Function for RN7SL744P Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
- Search ViGene Biosciences for RN7SL744P
CRISPR Products
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miRNA Products
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Inhibitory RNA Products
- Search ViGene Biosciences for RN7SL744P
Clone Products
- GenScript: Custom all cDNA clones Services for RN7SL744P
- VectorBuilder custom plasmid, inducible vectors for RN7SL744P
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RN7SL744P
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for RN7SL744P
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SL744P Gene
Localization for RN7SL744P Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RN7SL744P Gene
Transcripts for RN7SL744P Gene
mRNA/cDNA for RN7SL744P Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for RN7SL744P
miRNA Products
- Search ViGene Biosciences for RN7SL744P
Inhibitory RNA Products
- Search ViGene Biosciences for RN7SL744P
Clone Products
- GenScript: Custom all cDNA clones Services for RN7SL744P
- VectorBuilder custom plasmid, inducible vectors for RN7SL744P
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RN7SL744P
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for RN7SL744P Gene
NURSA nuclear receptor signaling pathways regulating expression of RN7SL744P Gene:
RN7SL744PPrimer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SL744P Gene
Orthologs for RN7SL744P Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | Metazoa_SRP 35 |
|
OneToOne |
- Species where no ortholog for RN7SL744P was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for RN7SL744P Gene
No data available for Paralogs for RN7SL744P Gene
Variants for RN7SL744P Gene
Relevant External Links for RN7SL744P Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RN7SL744P
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SL744P Gene
Disorders for RN7SL744P Gene
No disorders were found for RN7SL744P Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SL744P Gene
Publications for RN7SL744P Gene
No publications were found for RN7SL744P Gene.
Products for RN7SL744P Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for RN7SL744P
- VectorBuilder custom plasmid, inducible vectors for RN7SL744P
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RN7SL744P
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RN7SL744P Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
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- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
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- (42) dbSNP
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- (44) GeneTests
- (45) HGMD
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- (68) Abcam
- (69) Novus
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- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
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