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Aliases for RN7SL624P Gene

Subcategory (RNA class) for RN7SL624P Gene

SRP

Aliases for RN7SL624P Gene

  • RNA, 7SL, Cytoplasmic 624, Pseudogene 2 3 5

External Ids for RN7SL624P Gene

Previous GeneCards Identifiers for RN7SL624P Gene

  • GC17P002109

Summaries for RN7SL624P Gene

GeneCards Summary for RN7SL624P Gene

RN7SL624P (RNA, 7SL, Cytoplasmic 624, Pseudogene) is a Pseudogene, and is affiliated with the SRP RNA class.

fRNAdb sequence ontologies for RN7SL624P Gene

  • Metazoan signal recognition particle RNA: The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures, as represented by this family. Eight helical elements fold into the Alu and S domains, separated by a long linker region [1,2]. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP [1]. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition [2,3]. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54 binding [1]. The Signal Recognition Particle Database (SRPDB) [4] provides compilations of SRP components, with phylogenetic data and structural illustrations. Many sequences below the threshold for this family are clearly closely related, but are most likely to be SRP RNA derived pseudogenes. The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. While the threshold of this family is set high so as to minimise the number of hits to such regions, it is likely that some remain.

View fRNAdb secondary structures for RN7SL624P

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SL624P Gene

Genomics for RN7SL624P Gene

Regulatory Elements for RN7SL624P Gene

Enhancers for RN7SL624P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G002188 2.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -8.2 -8213 5.2 FOXA2 PKNOX1 SIN3A ARID4B FEZF1 ZNF48 YY1 TCF12 SLC30A9 GATA2 SRR ENSG00000236838 WDR81 RN7SL624P GC17M002154
GH17G002194 1.3 Ensembl ENCODE dbSUPER 0.7 -4.1 -4145 2.0 ZBTB21 NFIB ZFHX2 FOS IKZF2 EGR2 ZNF263 NFIA BHLHE40 USF2 HNRNPA1P16 METTL16 SRR ENSG00000263345 SMG6 RPA1 SMYD4 RN7SL624P GC17M002154
GH17G002198 0.9 ENCODE dbSUPER 0.7 -0.6 -639 0.9 ZNF263 ZNF146 ZNF362 ZFP37 ZNF501 ZSCAN21 ZNF366 HMBOX1 PRDM10 PRDM1 SRR LOC101927839 ENSG00000236838 RN7SL624P GC17M002154
GH17G002202 0.7 ENCODE dbSUPER 0.7 +3.2 3152 1.4 PRDM1 NR2F2 LOC101927839 RN7SL624P ENSG00000236838
GH17G002204 0.6 dbSUPER 0.7 +4.7 4661 0.5 ZNF121 GATA2 JUN IKZF1 FOS NR2F2 LOC101927839 RN7SL624P ENSG00000236838
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RN7SL624P on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SL624P Gene

Chromosome:
17
Start:
2,199,762 bp from pter
End:
2,200,039 bp from pter
Size:
278 bases
Orientation:
Plus strand

Genomic View for RN7SL624P Gene

Genes around RN7SL624P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SL624P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SL624P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for RN7SL624P Gene

ORGUL Member Location for RN7SL624P gene

No data available for RefSeq DNA sequence for RN7SL624P Gene

Proteins for RN7SL624P Gene

Post-translational modifications for RN7SL624P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SL624P Gene

Domains & Families for RN7SL624P Gene

Gene Families for RN7SL624P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RN7SL624P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SL624P Gene

Function for RN7SL624P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SL624P Gene

Localization for RN7SL624P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RN7SL624P Gene

Pathways & Interactions for RN7SL624P Gene

SuperPathways for RN7SL624P Gene

No Data Available

Interacting Proteins for RN7SL624P Gene

Gene Ontology (GO) - Biological Process for RN7SL624P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RN7SL624P Gene

Drugs & Compounds for RN7SL624P Gene

No Compound Related Data Available

Transcripts for RN7SL624P Gene

fRNAdb Secondary structures for RN7SL624P Gene

  • RF00017;Metazoa_SRP;AADC01128050.1/37205-37482

mRNA/cDNA for RN7SL624P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SL624P Gene

No ASD Table

Relevant External Links for RN7SL624P Gene

GeneLoc Exon Structure for
RN7SL624P
ECgene alternative splicing isoforms for
RN7SL624P

Expression for RN7SL624P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RN7SL624P Gene

NURSA nuclear receptor signaling pathways regulating expression of RN7SL624P Gene:

RN7SL624P
genes like me logo Genes that share expression patterns with RN7SL624P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SL624P Gene

Orthologs for RN7SL624P Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for RN7SL624P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia Metazoa_SRP 35
  • 76 (a)
OneToOne
Species where no ortholog for RN7SL624P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RN7SL624P Gene

ENSEMBL:
Gene Tree for RN7SL624P (if available)
TreeFam:
Gene Tree for RN7SL624P (if available)

Paralogs for RN7SL624P Gene

No data available for Paralogs for RN7SL624P Gene

Variants for RN7SL624P Gene

Relevant External Links for RN7SL624P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RN7SL624P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SL624P Gene

Disorders for RN7SL624P Gene

No disorders were found for RN7SL624P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SL624P Gene

Publications for RN7SL624P Gene

  1. SRPDB: Signal Recognition Particle Database. (PMID: 12520023) Rosenblad M.A. … Samuelsson T. (Nucleic Acids Res. 2003) 1
  2. Towards the structure of the mammalian signal recognition particle. (PMID: 11839493) Wild K. … Cusack S. (Curr. Opin. Struct. Biol. 2002) 1
  3. Prediction of signal recognition particle RNA genes. (PMID: 12140321) Regalia M. … Samuelsson T. (Nucleic Acids Res. 2002) 1
  4. Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle. (PMID: 11243816) Batey R.T. … Doudna J.A. (J. Mol. Biol. 2001) 1
  5. Crystal structure of the ribonucleoprotein core of the signal recognition particle. (PMID: 10678824) Batey R.T. … Doudna J.A. (Science 2000) 1

Products for RN7SL624P Gene

Sources for RN7SL624P Gene

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