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Aliases for RN7SL268P Gene

Subcategory (RNA class) for RN7SL268P Gene

SRP

Aliases for RN7SL268P Gene

  • RNA, 7SL, Cytoplasmic 268, Pseudogene 2 3 5

External Ids for RN7SL268P Gene

ORGUL Members for RN7SL268P Gene

Previous GeneCards Identifiers for RN7SL268P Gene

  • GC22M024223

Summaries for RN7SL268P Gene

GeneCards Summary for RN7SL268P Gene

RN7SL268P (RNA, 7SL, Cytoplasmic 268, Pseudogene) is a Pseudogene, and is affiliated with the SRP RNA class.

fRNAdb sequence ontologies for RN7SL268P Gene

  • Metazoan signal recognition particle RNA: The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures, as represented by this family. Eight helical elements fold into the Alu and S domains, separated by a long linker region [1,2]. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP [1]. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition [2,3]. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54 binding [1]. The Signal Recognition Particle Database (SRPDB) [4] provides compilations of SRP components, with phylogenetic data and structural illustrations. Many sequences below the threshold for this family are clearly closely related, but are most likely to be SRP RNA derived pseudogenes. The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. While the threshold of this family is set high so as to minimise the number of hits to such regions, it is likely that some remain.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SL268P Gene

Genomics for RN7SL268P Gene

Regulatory Elements for RN7SL268P Gene

Enhancers for RN7SL268P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F023692 1 Ensembl ENCODE 10.5 +184.5 184462 6.5 CTCF EBF1 ZNF121 POLR2A EED CREM SCRT1 ZNF680 REST MIER2 ENSG00000234353 C22orf15 CHCHD10 MMP11 VPREB3 ZNF70 SMARCB1 ENSG00000251357 SLC2A11 RN7SL268P
GH22F024058 1 Ensembl ENCODE 10.4 -180.2 -180232 3.3 SCRT1 NFIA JUN BHLHE40 ZIC2 RAD21 NR2F2 ZNF121 JUND SCRT2 SUSD2 MIF MIF-AS1 RN7SL268P ENSG00000251357 SLC2A11 POM121L9P ENSG00000232545 CABIN1
GH22F024042 0.9 ENCODE 10.7 -163.5 -163524 0.7 ELF3 MLX ARID4B ZSCAN9 RAD21 RARA YY1 FOS CREM MIXL1 MIF-AS1 MIF RN7SL268P ENSG00000251357 SLC2A11 CABIN1 ENSG00000232545
GH22F023700 0.9 ENCODE 10.5 +178.9 178922 0.2 ELF3 MLX ARID4B DMAP1 ZSCAN9 RAD21 YY1 RARA FOS CREM C22orf15 CHCHD10 MMP11 VPREB3 ZNF70 SMARCB1 SLC2A11 ENSG00000251357 RN7SL268P MIF
GH22F024037 0.8 ENCODE 10.7 -158.6 -158611 2.0 HDGF PKNOX1 ZBTB40 ZNF121 ZNF207 ETV6 CREM ZNF680 HCFC1 SMAD5 MIF-AS1 MIF RN7SL268P ENSG00000251357 SLC2A11 ENSG00000272578 SUSD2 CABIN1 ENSG00000232545
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RN7SL268P on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SL268P Gene

Chromosome:
22
Start:
23,879,493 bp from pter
End:
23,879,790 bp from pter
Size:
298 bases
Orientation:
Minus strand

Genomic View for RN7SL268P Gene

Genes around RN7SL268P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SL268P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SL268P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SL268P Gene

Proteins for RN7SL268P Gene

Post-translational modifications for RN7SL268P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SL268P Gene

Domains & Families for RN7SL268P Gene

Gene Families for RN7SL268P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RN7SL268P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SL268P Gene

Function for RN7SL268P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SL268P Gene

Localization for RN7SL268P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RN7SL268P Gene

Pathways & Interactions for RN7SL268P Gene

SuperPathways for RN7SL268P Gene

No Data Available

Interacting Proteins for RN7SL268P Gene

Gene Ontology (GO) - Biological Process for RN7SL268P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RN7SL268P Gene

Transcripts for RN7SL268P Gene

mRNA/cDNA for RN7SL268P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SL268P Gene

No ASD Table

Relevant External Links for RN7SL268P Gene

GeneLoc Exon Structure for
RN7SL268P
ECgene alternative splicing isoforms for
RN7SL268P

Expression for RN7SL268P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RN7SL268P Gene

mRNA differential expression in normal tissues according to GTEx for RN7SL268P Gene

This gene is overexpressed in Brain - Cerebellum (x4.8) and Brain - Cerebellar Hemisphere (x4.7).

NURSA nuclear receptor signaling pathways regulating expression of RN7SL268P Gene:

RN7SL268P
genes like me logo Genes that share expression patterns with RN7SL268P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RN7SL268P Gene

Orthologs for RN7SL268P Gene

Evolution for RN7SL268P Gene

ENSEMBL:
Gene Tree for RN7SL268P (if available)
TreeFam:
Gene Tree for RN7SL268P (if available)

No data available for Orthologs for RN7SL268P Gene

Paralogs for RN7SL268P Gene

No data available for Paralogs for RN7SL268P Gene

Variants for RN7SL268P Gene

Relevant External Links for RN7SL268P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RN7SL268P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SL268P Gene

Disorders for RN7SL268P Gene

No disorders were found for RN7SL268P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SL268P Gene

Publications for RN7SL268P Gene

No publications were found for RN7SL268P Gene.

Products for RN7SL268P Gene

Sources for RN7SL268P Gene

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