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Aliases for RN7SL1 Gene

Subcategory (RNA class) for RN7SL1 Gene

SRP

Quality Score for this RNA gene is

3

Aliases for RN7SL1 Gene

  • RNA, 7SL, Cytoplasmic 1 5 2 3
  • RNA, 7SL, Cytoplasmic 2
  • RNSRP1 3
  • RN7SL 3
  • 7L1a 3
  • 7SL 3

External Ids for RN7SL1 Gene

ORGUL Members for RN7SL1 Gene

Previous HGNC Symbols for RN7SL1 Gene

  • RN7SL

Previous GeneCards Identifiers for RN7SL1 Gene

  • GC00U911064
  • GC14U900430
  • GC14P049126
  • GC14P050053
  • GC14P049588
  • GC14P049590

Summaries for RN7SL1 Gene

Entrez Gene Summary for RN7SL1 Gene

  • The signal recognition particle (SRP) is a cytoplasmic ribonucleoprotein complex that mediates cotranslational insertion of secretory proteins into the lumen of the endoplasmic reticulum. The SRP consists of 6 polypeptides (e.g., SRP19; MIM 182175) and a 7SL RNA molecule, such as RN7SL1, that is partially homologous to Alu DNA (Ullu and Weiner, 1984 [PubMed 6084597]).[supplied by OMIM, Jul 2008]

GeneCards Summary for RN7SL1 Gene

RN7SL1 (RNA, 7SL, Cytoplasmic 1) is an RNA Gene, and is affiliated with the SRP RNA class.

Gene Wiki entry for RN7SL1 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RN7SL1 Gene

Genomics for RN7SL1 Gene

Regulatory Elements for RN7SL1 Gene


Promoters for RN7SL1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RN7SL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SL1 Gene

Chromosome:
14
Start:
49,586,580 bp from pter
End:
49,586,878 bp from pter
Size:
299 bases
Orientation:
Plus strand

Genomic View for RN7SL1 Gene

Genes around RN7SL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SL1 Gene

Proteins for RN7SL1 Gene

Post-translational modifications for RN7SL1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SL1 Gene

Domains & Families for RN7SL1 Gene

Gene Families for RN7SL1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RN7SL1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SL1 Gene

Function for RN7SL1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SL1 Gene

Localization for RN7SL1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RN7SL1 Gene COMPARTMENTS Subcellular localization image for RN7SL1 gene
Compartment Confidence
endoplasmic reticulum 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RN7SL1 Gene

Pathways & Interactions for RN7SL1 Gene

SuperPathways for RN7SL1 Gene

No Data Available

Interacting Proteins for RN7SL1 Gene

Gene Ontology (GO) - Biological Process for RN7SL1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RN7SL1 Gene

Drugs & Compounds for RN7SL1 Gene

No Compound Related Data Available

Transcripts for RN7SL1 Gene

mRNA/cDNA for RN7SL1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SL1 Gene

No ASD Table

Relevant External Links for RN7SL1 Gene

GeneLoc Exon Structure for
RN7SL1
ECgene alternative splicing isoforms for
RN7SL1

Expression for RN7SL1 Gene

mRNA expression in normal human tissues for RN7SL1 Gene

mRNA differential expression in normal tissues according to GTEx for RN7SL1 Gene

This gene is overexpressed in Whole Blood (x7.2).
genes like me logo Genes that share expression patterns with RN7SL1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RN7SL1 Gene

Orthologs for RN7SL1 Gene

Evolution for RN7SL1 Gene

ENSEMBL:
Gene Tree for RN7SL1 (if available)
TreeFam:
Gene Tree for RN7SL1 (if available)

No data available for Orthologs for RN7SL1 Gene

Paralogs for RN7SL1 Gene

No data available for Paralogs for RN7SL1 Gene

Variants for RN7SL1 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for RN7SL1 Gene

Disorders for RN7SL1 Gene

No disorders were found for RN7SL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SL1 Gene

Publications for RN7SL1 Gene

  1. Novel upstream and intragenic control elements for the RNA polymerase III-dependent transcription of human 7SL RNA genes. (PMID: 15667936) Englert M. … Beier H. (Biochimie 2004) 2 3 67
  2. Induced structural changes of 7SL RNA during the assembly of human signal recognition particle. (PMID: 12244299) Kuglstatter A. … Nagai K. (Nat. Struct. Biol. 2002) 3 23
  3. Human genes and pseudogenes for the 7SL RNA component of signal recognition particle. (PMID: 6084597) Ullu E. … Weiner A.M. (EMBO J. 1984) 2 3
  4. Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. (PMID: 23221635) Piazzon N. … Massenet S. (Nucleic Acids Res. 2013) 3
  5. Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging. (PMID: 18067920) Wang T. … Yu X.F. (J. Mol. Biol. 2008) 3

Products for RN7SL1 Gene

Sources for RN7SL1 Gene

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