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Aliases for RN7SKP277 Gene

Subcategory (RNA class) for RN7SKP277 Gene


Aliases for RN7SKP277 Gene

  • RNA, 7SK Small Nuclear Pseudogene 277 2 3 5

External Ids for RN7SKP277 Gene

Previous GeneCards Identifiers for RN7SKP277 Gene

  • GC07P121379

Summaries for RN7SKP277 Gene

GeneCards Summary for RN7SKP277 Gene

RN7SKP277 (RNA, 7SK Small Nuclear Pseudogene 277) is a Pseudogene, and is affiliated with the 7SK RNA class.

fRNAdb sequence ontologies for RN7SKP277 Gene - the ORGUL cluster for this gene includes several descriptions:

  • snRNA: A small nuclear RNA molecule involved in pre-mRNA splicing and processing.

  • 7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.

View fRNAdb secondary structures for RN7SKP277

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SKP277 Gene

Genomics for RN7SKP277 Gene

Regulatory Elements for RN7SKP277 Gene

Enhancers for RN7SKP277 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F121741 0.2 ENCODE 0.4 +5.8 5819 1.2 CEBPG ZBTB40 ATF2 RN7SKP277 PNPT1P2
GH07F121743 0.4 ENCODE 0.4 +8.4 8398 1.7 JUNB TRIM22 REST TBX21 ZBTB40 TARDBP MLLT1 ETV6 CREM RN7SKP277 PNPT1P2
GH07F121713 1.1 ENCODE 0.3 -21.6 -21571 3.0 SOX13 SAP130 ZFP64 CEBPG ZNF644 TEAD3 YY1 ZFHX2 ZNF316 RFXANK RN7SKP277 ENSG00000227743
GH07F121714 0.8 ENCODE 0.3 -23.3 -23322 0.2 SOX13 GATAD2A SP5 FOXA3 ZNF644 KAT8 ZFHX2 EGR2 RN7SKP277 ENSG00000227743
GH07F121794 1.3 FANTOM5 ENCODE 0.2 +61.1 61092 5.1 HDGF ATF1 PKNOX1 ARNT CREB3L1 SIN3A GLIS2 ZNF766 SP3 SP5 PTPRZ1 PNPT1P2 RN7SKP277
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RN7SKP277 on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SKP277 Gene

121,736,443 bp from pter
121,736,725 bp from pter
283 bases
Plus strand

Genomic View for RN7SKP277 Gene

Genes around RN7SKP277 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SKP277 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SKP277 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SKP277 Gene

ORGUL Member Location for RN7SKP277 Gene

ORGUL Member Location for RN7SKP277 gene

Proteins for RN7SKP277 Gene

Post-translational modifications for RN7SKP277 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SKP277 Gene

Domains & Families for RN7SKP277 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SKP277 Gene

Function for RN7SKP277 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SKP277 Gene

Localization for RN7SKP277 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RN7SKP277 Gene

Pathways & Interactions for RN7SKP277 Gene

SuperPathways for RN7SKP277 Gene

No Data Available

Interacting Proteins for RN7SKP277 Gene

Gene Ontology (GO) - Biological Process for RN7SKP277 Gene


No data available for Pathways by source and SIGNOR curated interactions for RN7SKP277 Gene

Transcripts for RN7SKP277 Gene

fRNAdb Secondary structures for RN7SKP277 Gene

  • RF00100;7SK;ADDF010269581.1/268-10

mRNA/cDNA for RN7SKP277 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SKP277 Gene

No ASD Table

Relevant External Links for RN7SKP277 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RN7SKP277 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RN7SKP277 Gene

NURSA nuclear receptor signaling pathways regulating expression of RN7SKP277 Gene:

genes like me logo Genes that share expression patterns with RN7SKP277: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RN7SKP277 Gene

Orthologs for RN7SKP277 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RN7SKP277 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia 7SK 35
  • 100 (a)
(Canis familiaris)
Mammalia 7SK 35
  • 57 (a)
(Bos Taurus)
Mammalia 7SK 35
  • 56 (a)
(Mus musculus)
Mammalia Gm23068 35
  • 41 (a)
(Danio rerio)
Actinopterygii 7SK 35
  • 45 (a)
Species where no ortholog for RN7SKP277 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RN7SKP277 Gene

Gene Tree for RN7SKP277 (if available)
Gene Tree for RN7SKP277 (if available)

Paralogs for RN7SKP277 Gene

No data available for Paralogs for RN7SKP277 Gene

Variants for RN7SKP277 Gene

Relevant External Links for RN7SKP277 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SKP277 Gene

Disorders for RN7SKP277 Gene

No disorders were found for RN7SKP277 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SKP277 Gene

Publications for RN7SKP277 Gene

  1. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C. … Chen R. (Nucleic Acids Res. 2005) 1
  2. Transcription: surprising role for an elusive small nuclear RNA. (PMID: 11864590) Blencowe B.J. (Curr. Biol. 2002) 1

Products for RN7SKP277 Gene

Sources for RN7SKP277 Gene

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