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Aliases for RN7SKP259 Gene

Subcategory (RNA class) for RN7SKP259 Gene

7SK RNA

Aliases for RN7SKP259 Gene

  • RNA, 7SK Small Nuclear Pseudogene 259 2 3 5

External Ids for RN7SKP259 Gene

ORGUL Members for RN7SKP259 Gene

Previous GeneCards Identifiers for RN7SKP259 Gene

  • GC11P057223

Summaries for RN7SKP259 Gene

GeneCards Summary for RN7SKP259 Gene

RN7SKP259 (RNA, 7SK Small Nuclear Pseudogene 259) is a Pseudogene, and is affiliated with the 7SK RNA class.

fRNAdb sequence ontologies for RN7SKP259 Gene

  • 7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SKP259 Gene

Genomics for RN7SKP259 Gene

Regulatory Elements for RN7SKP259 Gene

Enhancers for RN7SKP259 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G057405 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.4 -44.9 -44924 2.4 PKNOX1 GATA2 FOS RELB ETV6 IKZF2 CREM JUNB GATAD2B REST SLC43A3 P2RX3 RN7SKP259 RTN4RL2 SSRP1 PRG2 TIMM10 UBE2L6 ZDHHC5 LOC105369312
GH11G057496 1.6 Ensembl ENCODE dbSUPER 11.7 +48.2 48239 6.7 HDGF PKNOX1 FOXA2 ARID4B DMAP1 YY1 FOS SP3 SP5 JUNB TIMM10 RTN4RL2 RN7SKP259 MIR130A SLC43A3 ENSG00000254979 P2RX3 SSRP1 ENSG00000254602 CLP1
GH11G057481 1.1 Ensembl ENCODE 13.2 +31.0 30987 2.2 RB1 AGO1 ZFP64 KLF17 ZNF48 RAD21 GLIS2 EGR1 ZNF366 ZNF143 TIMM10 SMTNL1 RTN4RL2 RN7SKP259 SLC43A1 SLC43A3 ENSG00000254979 P2RX3 SSRP1 UBE2L6
GH11G057402 1.2 ENCODE dbSUPER 11.2 -49.1 -49137 0.6 HDAC1 CBX3 ATF1 TBL1XR1 TCF12 GATA2 FOS CREM ZNF263 ZBTB2 ENSG00000254979 SLC43A3 RN7SKP259 RTN4RL2 SSRP1 P2RX3 LOC105369312 PRG2
GH11G057666 1.4 ENCODE dbSUPER 9.5 +216.8 216771 4.6 CREB3L1 MLX AGO1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 SSRP1 SSRP1 MED19 YPEL4 ENSG00000254732 SELENOH ENSG00000269570 BTBD18 CTNND1 RTN4RL2 RN7SKP259
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RN7SKP259 on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SKP259 Gene

Chromosome:
11
Start:
57,451,690 bp from pter
End:
57,452,022 bp from pter
Size:
333 bases
Orientation:
Plus strand

Genomic View for RN7SKP259 Gene

Genes around RN7SKP259 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SKP259 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SKP259 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SKP259 Gene

Proteins for RN7SKP259 Gene

Post-translational modifications for RN7SKP259 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SKP259 Gene

Domains & Families for RN7SKP259 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SKP259 Gene

Function for RN7SKP259 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SKP259 Gene

Localization for RN7SKP259 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RN7SKP259 Gene

Pathways & Interactions for RN7SKP259 Gene

SuperPathways for RN7SKP259 Gene

No Data Available

Interacting Proteins for RN7SKP259 Gene

Gene Ontology (GO) - Biological Process for RN7SKP259 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RN7SKP259 Gene

Drugs & Compounds for RN7SKP259 Gene

No Compound Related Data Available

Transcripts for RN7SKP259 Gene

mRNA/cDNA for RN7SKP259 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SKP259 Gene

No ASD Table

Relevant External Links for RN7SKP259 Gene

GeneLoc Exon Structure for
RN7SKP259
ECgene alternative splicing isoforms for
RN7SKP259

Expression for RN7SKP259 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RN7SKP259 Gene

NURSA nuclear receptor signaling pathways regulating expression of RN7SKP259 Gene:

RN7SKP259
genes like me logo Genes that share expression patterns with RN7SKP259: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SKP259 Gene

Orthologs for RN7SKP259 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RN7SKP259 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia 7SK 35
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm23171 35
  • 61 (a)
OneToMany
Gm22320 35
  • 55 (a)
OneToMany
Gm22483 35
  • 55 (a)
OneToMany
Gm23673 35
  • 47 (a)
OneToMany
dog
(Canis familiaris)
Mammalia 7SK 35
  • 51 (a)
ManyToMany
chicken
(Gallus gallus)
Aves 7SK 35
  • 47 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia 7SK 35
  • 43 (a)
ManyToMany
Species where no ortholog for RN7SKP259 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RN7SKP259 Gene

ENSEMBL:
Gene Tree for RN7SKP259 (if available)
TreeFam:
Gene Tree for RN7SKP259 (if available)

Paralogs for RN7SKP259 Gene

No data available for Paralogs for RN7SKP259 Gene

Variants for RN7SKP259 Gene

Relevant External Links for RN7SKP259 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RN7SKP259

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SKP259 Gene

Disorders for RN7SKP259 Gene

No disorders were found for RN7SKP259 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SKP259 Gene

Publications for RN7SKP259 Gene

No publications were found for RN7SKP259 Gene.

Products for RN7SKP259 Gene

Sources for RN7SKP259 Gene

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