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Aliases for RN7SKP248 Gene

Subcategory (RNA class) for RN7SKP248 Gene

7SK RNA

Aliases for RN7SKP248 Gene

  • RNA, 7SK Small Nuclear Pseudogene 248 2 3 5

External Ids for RN7SKP248 Gene

ORGUL Members for RN7SKP248 Gene

Previous GeneCards Identifiers for RN7SKP248 Gene

  • GC04P091293

Summaries for RN7SKP248 Gene

GeneCards Summary for RN7SKP248 Gene

RN7SKP248 (RNA, 7SK Small Nuclear Pseudogene 248) is a Pseudogene, and is affiliated with the 7SK RNA class.

fRNAdb sequence ontologies for RN7SKP248 Gene

  • 7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.

Additional gene information for RN7SKP248 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SKP248 Gene

Genomics for RN7SKP248 Gene

Regulatory Elements for RN7SKP248 Gene

Enhancers for RN7SKP248 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H090317 1.2 FANTOM5 Ensembl ENCODE 0.2 -51.7 -51720 2 PKNOX1 ARNT JUN USF2 CHD1 CEBPB ZIC2 JUND MAFF POLR2A RN7SKP248 GC04P090217 PIR31490
GH04H090442 0.4 ENCODE 0.2 +73.4 73391 1 CEBPB RN7SKP248 ENSG00000251401
GH04H090532 0.5 FANTOM5 0.1 +162.9 162856 0 CTCF ENSG00000251401 RN7SKP248
GH04H090280 0.2 ENCODE 0.2 -88.8 -88800 1 CCSER1 GC04P090217 PIR31490 RN7SKP248
GH04H090546 0.4 ENCODE 0.1 +176.2 176162 0 ETV6 RUNX3 ENSG00000251401 RN7SKP248
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RN7SKP248 on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SKP248 Gene

Chromosome:
4
Start:
90,370,123 bp from pter
End:
90,370,427 bp from pter
Size:
305 bases
Orientation:
Plus strand

Genomic View for RN7SKP248 Gene

Genes around RN7SKP248 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SKP248 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SKP248 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SKP248 Gene

Proteins for RN7SKP248 Gene

Post-translational modifications for RN7SKP248 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SKP248 Gene

Domains & Families for RN7SKP248 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SKP248 Gene

Function for RN7SKP248 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SKP248 Gene

Localization for RN7SKP248 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RN7SKP248 Gene

Pathways & Interactions for RN7SKP248 Gene

SuperPathways for RN7SKP248 Gene

No Data Available

Interacting Proteins for RN7SKP248 Gene

Gene Ontology (GO) - Biological Process for RN7SKP248 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RN7SKP248 Gene

Drugs & Compounds for RN7SKP248 Gene

No Compound Related Data Available

Transcripts for RN7SKP248 Gene

mRNA/cDNA for RN7SKP248 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SKP248 Gene

No ASD Table

Relevant External Links for RN7SKP248 Gene

GeneLoc Exon Structure for
RN7SKP248
ECgene alternative splicing isoforms for
RN7SKP248

Expression for RN7SKP248 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RN7SKP248 Gene

NURSA nuclear receptor signaling pathways regulating expression of RN7SKP248 Gene:

RN7SKP248
genes like me logo Genes that share expression patterns with RN7SKP248: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SKP248 Gene

Orthologs for RN7SKP248 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RN7SKP248 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia 7SK 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia 7SK 34
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25386 34
  • 44 (a)
OneToMany
Gm22552 34
  • 41 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii 7SK 34
  • 39 (a)
OneToMany
Species where no ortholog for RN7SKP248 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RN7SKP248 Gene

ENSEMBL:
Gene Tree for RN7SKP248 (if available)
TreeFam:
Gene Tree for RN7SKP248 (if available)

Paralogs for RN7SKP248 Gene

No data available for Paralogs for RN7SKP248 Gene

Variants for RN7SKP248 Gene

Relevant External Links for RN7SKP248 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RN7SKP248

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SKP248 Gene

Disorders for RN7SKP248 Gene

No disorders were found for RN7SKP248 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SKP248 Gene

Publications for RN7SKP248 Gene

No publications were found for RN7SKP248 Gene.

Products for RN7SKP248 Gene

Sources for RN7SKP248 Gene

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