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Aliases for RN7SKP191 Gene

Subcategory (RNA class) for RN7SKP191 Gene


Aliases for RN7SKP191 Gene

  • RNA, 7SK Small Nuclear Pseudogene 191 2 3 5

External Ids for RN7SKP191 Gene

Previous GeneCards Identifiers for RN7SKP191 Gene

  • GC09P107862

Summaries for RN7SKP191 Gene

GeneCards Summary for RN7SKP191 Gene

RN7SKP191 (RNA, 7SK Small Nuclear Pseudogene 191) is a Pseudogene, and is affiliated with the 7SK RNA class.

fRNAdb sequence ontologies for RN7SKP191 Gene - the ORGUL cluster for this gene includes several descriptions:

  • snRNA: A small nuclear RNA molecule involved in pre-mRNA splicing and processing.

  • 7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SKP191 Gene

Genomics for RN7SKP191 Gene

Regulatory Elements for RN7SKP191 Gene

Enhancers for RN7SKP191 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F105126 1.2 FANTOM5 Ensembl ENCODE 0.3 +30.9 30945 3.4 MTA2 TEAD1 BHLHE40 CEBPB CEBPG GABPA NR2F2 RARA TEAD3 CEBPA ABCA1 RN7SKP191 GC09P105218
GH09F105114 0.9 Ensembl ENCODE 0.3 +18.9 18875 3.3 MAX RAD21 GABPA NR2F2 RARA YY1 ATF3 HNF4G ZBTB33 MYC ABCA1 LOC105376196 RN7SKP191 GC09P105218
GH09F105140 1.3 FANTOM5 Ensembl ENCODE 0.2 +45.0 45046 2.8 ZNF316 POLR2A SMARCA4 HLF MAFG NFE2 EMSY SPI1 ABCA1 RN7SKP191 GC09P105218
GH09F105132 0.6 ENCODE 0.3 +35.9 35872 1.2 CTCF GATA3 JUND BHLHE40 SIN3A FOS TCF7L2 RN7SKP191 GC09P105218
GH09F105138 0.9 Ensembl ENCODE 0.2 +42.2 42215 1.3 SOX13 FOXA3 HMG20A PPARG HHEX SMARCA4 RERE POLR2A CTBP2 KDM1A RN7SKP191 GC09P105218
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RN7SKP191 on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SKP191 Gene

105,096,756 bp from pter
105,097,061 bp from pter
306 bases
Plus strand

Genomic View for RN7SKP191 Gene

Genes around RN7SKP191 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SKP191 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SKP191 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SKP191 Gene

ORGUL Member Location for RN7SKP191 Gene

ORGUL Member Location for RN7SKP191 gene

Proteins for RN7SKP191 Gene

Post-translational modifications for RN7SKP191 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SKP191 Gene

Domains & Families for RN7SKP191 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SKP191 Gene

Function for RN7SKP191 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SKP191 Gene

Localization for RN7SKP191 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RN7SKP191 Gene

Pathways & Interactions for RN7SKP191 Gene

SuperPathways for RN7SKP191 Gene

No Data Available

Interacting Proteins for RN7SKP191 Gene

Gene Ontology (GO) - Biological Process for RN7SKP191 Gene


No data available for Pathways by source and SIGNOR curated interactions for RN7SKP191 Gene

Transcripts for RN7SKP191 Gene

mRNA/cDNA for RN7SKP191 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SKP191 Gene

No ASD Table

Relevant External Links for RN7SKP191 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RN7SKP191 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RN7SKP191 Gene

NURSA nuclear receptor signaling pathways regulating expression of RN7SKP191 Gene:

genes like me logo Genes that share expression patterns with RN7SKP191: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RN7SKP191 Gene

Orthologs for RN7SKP191 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RN7SKP191 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia 7SK 35
  • 99 (a)
(Bos Taurus)
Mammalia 7SK 35
  • 73 (a)
(Mus musculus)
Mammalia Gm24140 35
  • 65 (a)
(Anolis carolinensis)
Reptilia 7SK 35
  • 63 (a)
Species where no ortholog for RN7SKP191 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RN7SKP191 Gene

Gene Tree for RN7SKP191 (if available)
Gene Tree for RN7SKP191 (if available)

Paralogs for RN7SKP191 Gene

No data available for Paralogs for RN7SKP191 Gene

Variants for RN7SKP191 Gene

Relevant External Links for RN7SKP191 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SKP191 Gene

Disorders for RN7SKP191 Gene

No disorders were found for RN7SKP191 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SKP191 Gene

Publications for RN7SKP191 Gene

  1. Transcription: surprising role for an elusive small nuclear RNA. (PMID: 11864590) Blencowe B.J. (Curr. Biol. 2002) 1
  2. Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function. (PMID: 1646389) Wassarman D.A. … Steitz J.A. (Mol. Cell. Biol. 1991) 1

Products for RN7SKP191 Gene

Sources for RN7SKP191 Gene

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