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Aliases for RN7SKP169 Gene

Subcategory (RNA class) for RN7SKP169 Gene

7SK RNA

Aliases for RN7SKP169 Gene

  • RNA, 7SK Small Nuclear Pseudogene 169 2 3 5

External Ids for RN7SKP169 Gene

ORGUL Members for RN7SKP169 Gene

Previous GeneCards Identifiers for RN7SKP169 Gene

  • GC22M026361

Summaries for RN7SKP169 Gene

GeneCards Summary for RN7SKP169 Gene

RN7SKP169 (RNA, 7SK Small Nuclear Pseudogene 169) is a Pseudogene, and is affiliated with the 7SK RNA class.

fRNAdb sequence ontologies for RN7SKP169 Gene

  • 7SK RNA: 7SK was discovered as an abundant small nuclear RNA in the mid-70s but a possible function has only recently been suggested [1]. Two independent studies have found that 7SK RNA binds the CDK9/cyclin T complex (known as elongation factor P-TEFb). P-TEFb activates transcription by phosphorylating the C-terminal domain of RNA polymerase II. This process is negatively regulated by the 7SK RNP. The secondary structure of 7SK RNA shown here was proposed by Wasserman and Steitz on the basis of chemical modification and enzymatic cleavage experiments [2]. This family contains a number of annotated pseudogenes and 7SK derived repeats. The threshold is artificially high to minimise the pseudogene count.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RN7SKP169 Gene

Genomics for RN7SKP169 Gene

Regulatory Elements for RN7SKP169 Gene

Enhancers for RN7SKP169 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G025966 0.9 ENCODE 0.7 -2.5 -2461 0.5 PKNOX1 INSM2 FEZF1 ZSCAN5C RELB ZNF391 IKZF2 OVOL3 TSHZ1 ZNF488 RN7SKP169 ENSG00000232464
GH22G025970 0.9 ENCODE 0.4 -6.8 -6760 1.8 YBX1 RAD21 ZBTB40 ZNF121 EGR1 ZNF366 ZSCAN5C ZNF143 ZNF391 IKZF2 ENSG00000272977 LOC100507599 CRYBB2P1 RN7SKP169 ENSG00000232464
GH22G025941 0.9 ENCODE 0.3 +21.7 21748 2.5 PKNOX1 FEZF1 ZNF2 GLIS2 FOS ZNF263 YY2 TSHZ1 ZNF488 ZNF623 ENSG00000232464 RN7SKP169 PIR31495
GH22G025935 0.6 ENCODE 0.3 +28.8 28805 0.2 CTCF SMC3 TRIM22 EP300 PRDM1 RAD21 ENSG00000232464 LOC105372963 MYO18B RN7SKP169 PIR31495
GH22G025928 0.6 ENCODE 0.3 +36.0 36045 0.2 ZSCAN4 ZNF16 ZNF121 OSR2 NFIC GLIS1 KDM1A SP7 PIR31495 RN7SKP169
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RN7SKP169 on UCSC Golden Path with GeneCards custom track

Genomic Location for RN7SKP169 Gene

Chromosome:
22
Start:
25,963,983 bp from pter
End:
25,964,273 bp from pter
Size:
291 bases
Orientation:
Minus strand

Genomic View for RN7SKP169 Gene

Genes around RN7SKP169 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RN7SKP169 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RN7SKP169 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RN7SKP169 Gene

Proteins for RN7SKP169 Gene

Post-translational modifications for RN7SKP169 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RN7SKP169 Gene

Domains & Families for RN7SKP169 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RN7SKP169 Gene

Function for RN7SKP169 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RN7SKP169 Gene

Localization for RN7SKP169 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RN7SKP169 Gene

Pathways & Interactions for RN7SKP169 Gene

SuperPathways for RN7SKP169 Gene

No Data Available

Interacting Proteins for RN7SKP169 Gene

Gene Ontology (GO) - Biological Process for RN7SKP169 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RN7SKP169 Gene

Drugs & Compounds for RN7SKP169 Gene

No Compound Related Data Available

Transcripts for RN7SKP169 Gene

mRNA/cDNA for RN7SKP169 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RN7SKP169 Gene

No ASD Table

Relevant External Links for RN7SKP169 Gene

GeneLoc Exon Structure for
RN7SKP169
ECgene alternative splicing isoforms for
RN7SKP169

Expression for RN7SKP169 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RN7SKP169 Gene

mRNA differential expression in normal tissues according to GTEx for RN7SKP169 Gene

This gene is overexpressed in Heart - Atrial Appendage (x26.0), Heart - Left Ventricle (x13.2), Muscle - Skeletal (x7.6), and Testis (x6.2).

NURSA nuclear receptor signaling pathways regulating expression of RN7SKP169 Gene:

RN7SKP169
genes like me logo Genes that share expression patterns with RN7SKP169: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RN7SKP169 Gene

Orthologs for RN7SKP169 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RN7SKP169 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia 7SK 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia 7SK 35
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia 7SK 35
  • 59 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm24636 35
  • 55 (a)
OneToOne
Species where no ortholog for RN7SKP169 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RN7SKP169 Gene

ENSEMBL:
Gene Tree for RN7SKP169 (if available)
TreeFam:
Gene Tree for RN7SKP169 (if available)

Paralogs for RN7SKP169 Gene

No data available for Paralogs for RN7SKP169 Gene

Variants for RN7SKP169 Gene

Relevant External Links for RN7SKP169 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RN7SKP169

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RN7SKP169 Gene

Disorders for RN7SKP169 Gene

No disorders were found for RN7SKP169 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RN7SKP169 Gene

Publications for RN7SKP169 Gene

No publications were found for RN7SKP169 Gene.

Products for RN7SKP169 Gene

Sources for RN7SKP169 Gene

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