RN5S1@ Cluster
gene cluster GIFtS: 16
GCID: GC01U990136
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RNA, 5S ribosomal 1q42 cluster(Previous names: RNA, 5S cluster 1 )
(Previous symbol: RN5S)
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Aliases
for RN5S1@ gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RNA, 5S Ribosomal 1q42 Cluster1 2 | | RN5S1 2 | | RNA, 5S Cluster 11 |
Export aliases for RN5S1@ gene to outside databases |
Summaries
for RN5S1@ gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for RN5S1@
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Genomic Views
for RN5S1@ gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for RN5S1@
Other transcription factors
Search SABiosciences Chromatin IP Primers for RN5S1@
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RN5S1@ |
Genomic Location:
Chromosome:1
Entrez Gene cytogenetic band: 1q42.11-q42.13 HGNC cytogenetic band: 1q42.11-q42.13GeneLoc information about chromosome 1 |
Proteins
for RN5S1@ gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for RN5S1@ gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for RN5S1@ gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Function Summary:
Genatlas biochemistry entry for RN5S1@:RNA,5S cluster 1 (90 repeat units)
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Pathways & Interactions
for RN5S1@ gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table 
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis of PB1-F2 | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  GeneGo (Thomson Reuters) Pathway for RN5S1@
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RN5S1@
|
Drugs & Compounds
for RN5S1@ gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RN5S1@
Search CenterWatch for drugs/clinical trials and news about RN5S1@
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Transcripts
for RN5S1@ gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Expression
for RN5S1@ gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for RN5S1@:none
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
SABiosciences Custom PCR Arrays for RN5S1@
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat RN5S1@ | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RN5S1@ | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RN5S1@ |
Orthologs
for RN5S1@ gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of human and mouse.
Orthologs for RN5S1@ gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Rn5s5 |
5S RNA |
-- |
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8 (72.10 cM) 123598158 |
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Paralogs
for RN5S1@ gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for RN5S1@ gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for RN5S1@ gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RN5S1@ for disorders About GeneDecksing
OMIM gene information: 180420
OMIM disorders: --
1  disease for RN5S1@: About MalaCardsadenocarcinoma
Human Genome Epidemiology (HuGE) Navigator: RN5S1@ (1 document)
Export disorders for RN5S1@ gene to outside databases
|
Publications
for RN5S1@ gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for RN5S1@ gene integrated from 9 sources:
(articles sorted by number of sources associating them with RN5S1@) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Localisation of 5S ribosomal RNA genes on human chromosome 1. (PubMed id 4437633)1, 3 Steffensen D.M....Prensky W. (1974)
- A critical role for noncoding 5S rRNA in regulating M dmx stability. (PubMed id 21925390)1 Li M. and Gu W. (2011)
- Cytokine gene polymorphisms and the risk of adenocarcinoma of the stomach in the European prospective investigation into cancer and nutrition (EPIC-EURGAST). (PubMed id 18628242)1 Crusius J.B....Gonzalez C.A. (2008)
- 5S rRNA gene hybridizes to human chromosome 1 at two sites (1q42.11-->q42.13 and 1q43). (PubMed id 7956368)1 Kost M.V....Zelenin A.V. (1995)
- Fine mapping of human 5S rRNA genes to chromosome 1q42.11----q42.13. (PubMed id 1855389)1 Sorensen P.D....Tommerup N. (1991)
- The nucleotide sequence of 5S rRNA from a cellular slime mold Dictyostelium discoideum. (PubMed id 7465421)1 Hori H....Iwabuchi M. (1980)
- Report of the committee on the genetic constitution of chromosome 1. (PubMed id 396131)1 Cook P.J. and Hamerton J.L. (1979)
- Proceedings: Localization of the 5S ribosomal RNA genes in the human genome. (PubMed id 4827485)1 Steffensen D.M....Dufy P. (1974)
- The nucleotide sequence of ribosomal 5 S ribonucleic acid from KB cells. (PubMed id 5792654)1 Forget B.G. and Weissman S.M. (1969)
- Nucleotide sequence of KB cell 5S RNA. (PubMed id 6059650)1 Forget B.G. and Weissman S.M. (1967)
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External Searches for RN5S1@ gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing RN5S1@ gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing RN5S1@ gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RN5S1@ gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RN5S1@ | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for RN5S1@ gene:
Search GeneIP for patents involving RN5S1@
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RN5S1@ gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RN5S1@ | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RN5S1@ | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RN5S1@ | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RN5S1@ | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RN5S1@ | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RN5S1@ |
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| | | | Search Tocris compounds for RN5S1@ |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for RN5S1@ |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RN5S1@ |
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