Aliases for RMST gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| Subcategory (RNA class): lncRNA
Quality score for this RNA gene is 5
| Aliases |
|---|
| Rhabdomyosarcoma 2 Associated Transcript (Non-Protein Coding)1 2 | | NCRMS1 2 5 | | NCRNA000541 2 5 | | LINC000541 2 |
| External Ids: | HGNC: 298931 | Entrez Gene: 1964752 | Ensembl: ENSG000002557947 | OMIM: 6070455 | Export aliases for RMST gene to outside databasesPrevious GC identifers: GC12P096362 GC12U900573
Summaries for RMST gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Gene Wiki entry for RMST
fRNAdb sequence ontology for RMST: ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.
|
Genomic Views for RMST gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the RMST gene promoter: GR TBP STAT5B POU3F1 POU6F1 (c2) Tal-1beta HEN1 FOXO4 GR-alpha ITF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for RMST
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RMST |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q23.1|12q21 Ensembl cytogenetic band: 12q23.1 HGNC cytogenetic band: 12q23.1RMST Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P097858: view genomic region
(about GC identifiers)
Start:
|
97,825,431 bp from pter |
End:
|
97,958,813 bp from pter |
Size:
|
133,383 bases |
Orientation:
|
plus strand |
ORGUL member locations: Legend (see complete legend)
 |
Proteins for RMST gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB: --
|
Protein
Domains / Families for RMST gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function for RMST gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Animal Models:
Cell Line Products: |  | GenScript Custom overexpressing Cell Line Services for RMST | |  | Search LifeMap BioReagents cell lines for RMST | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RMST |
Pathways & Interactions for RMST gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RMST
|
Drugs & Compounds for RMST gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for RMST Search CenterWatch for drugs/clinical trials and news about RMST 
|
Transcripts for RMST gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| Unigene Cluster for RMST: Rhabdomyosarcoma 2 associated transcript (non-protein coding) Hs.652568 [show with all ESTs]Unigene Representative Sequence: AK0561646 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000538559(lincRNA)(uc001tfa.1) ENST00000541282(lincRNA)(uc001tey.1) ENST00000548886(lincRNA)(uc001tez.1) ENST00000547996(lincRNA) ENST00000552411(lincRNA) ENST00000547946(lincRNA)
Additional cDNA sequence: AF429305.1 AF429306.1 AK056164.1 NR_024037.1 5 DOTS entries: DT.408059 DT.95123408 DT.97835174 DT.95218774 DT.95365073 24/28 AceView cDNA sequences (see all 28): BE468066 AK056164 AW073558 AW873986 AA935956 AA385037 AW103716 BM719242 BF448175 AI693605 CD107083 AA628719 AI279904 AA460684 BF195950 AF429306 AI860130 BG149972 BE551303 AA905859 AA460858 AF429305 BF447150 BE176737 GeneLoc Exon Structure
|
Expression for RMST gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for RMST:RNAdb
RMST expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTAATTTTGT
 About this image Genevestigator expression for RMST
SOURCE GeneReport for Unigene cluster: Hs.652568 SABiosciences Custom PCR Arrays for RMST
Primer Products: |  | Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
| |  | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat RMST | |  | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RMST | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RMST | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RMST |
Orthologs for RMST gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for RMST (if available) TreeFam Gene Tree for RMST (if available)  |
Paralogs for RMST gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for RMST gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 12 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for RMST (97825431 - 97958813 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for RMST 1 CNV: 1926  | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases for RMST gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RMST for disorders About GeneDecksing
OMIM gene information: 607045
OMIM disorders: --
1 disease for RMST: About MalaCardsrhabdomyosarcoma Export disorders for RMST gene to outside databases
|
Publications for RMST gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RMST gene integrated from 9 sources: (articles sorted by number of sources associating them with RMST) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Rmst is a novel marker for the mouse ventral mesencep halic floor plate and the anterior dorsal midline cells. (PubMed id 20062813)1, 3 Uhde C.W....Li M. (2010)
- Identification of a novel gene NCRMS on chromosome 12q21 with differential expression between rhabdomyosarcoma subtypes. (PubMed id 12082533)1, 3 Chan A.S....Zielenska M. (2002)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- (PubMed id 15872005)10
- (PubMed id 15608161)10
- (PubMed id 15608158)10
- (PubMed id 15103394)10
- (PubMed id 18089548)10
|
External Searches for RMST gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RMST gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RMST gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RMST gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for RMST | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RMST gene: Search GeneIP for patents involving RMST
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for RMST gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 |
| | | | |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RMST | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RMST | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RMST | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RMST | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RMST | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RMST |
| |
 |  |  |  | |
| | | Search Tocris compounds for RMST |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RMST |
|  |  |  |  | | | Search ThermoFisher Antibodies for RMST |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RMST |
| |  | |
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|
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