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Aliases for RMND5B Gene

Aliases for RMND5B Gene

  • Required For Meiotic Nuclear Division 5 Homolog B (S. Cerevisiae) 2 3
  • GID Complex Subunit 2 Homolog B 2 3
  • Protein RMD5 Homolog B 3
  • GID2B 3
  • GID2 3

External Ids for RMND5B Gene

Summaries for RMND5B Gene

GeneCards Summary for RMND5B Gene

RMND5B (Required For Meiotic Nuclear Division 5 Homolog B (S. Cerevisiae)) is a Protein Coding gene. An important paralog of this gene is RMND5A.

Gene Wiki entry for RMND5B Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RMND5B Gene

Genomics for RMND5B Gene

Genomic Location for RMND5B Gene

Start:
178,130,961 bp from pter
End:
178,150,565 bp from pter
Size:
19,605 bases
Orientation:
Plus strand

Genomic View for RMND5B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RMND5B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RMND5B Gene

Regulatory Elements for RMND5B Gene

Proteins for RMND5B Gene

  • Protein details for RMND5B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96G75-RMD5B_HUMAN
    Recommended name:
    Protein RMD5 homolog B
    Protein Accession:
    Q96G75
    Secondary Accessions:
    • Q1HE27
    • Q6UVY7
    • Q9H6F6

    Protein attributes for RMND5B Gene

    Size:
    393 amino acids
    Molecular mass:
    44414 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15303.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for RMND5B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RMND5B Gene

Proteomics data for RMND5B Gene at MOPED

Post-translational modifications for RMND5B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RMND5B Gene

Domains for RMND5B Gene

UniProtKB/Swiss-Prot:

RMD5B_HUMAN
Domain:
  • Contains 1 CTLH domain.:
    • Q96G75
  • Contains 1 LisH domain.:
    • Q96G75
genes like me logo Genes that share domains with RMND5B: view

No data available for Gene Families for RMND5B Gene

Function for RMND5B Gene

Gene Ontology (GO) - Molecular Function for RMND5B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with RMND5B: view

Phenotypes for RMND5B Gene

GenomeRNAi human phenotypes for RMND5B:
genes like me logo Genes that share phenotypes with RMND5B: view

miRNA for RMND5B Gene

miRTarBase miRNAs that target RMND5B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RMND5B Gene

Localization for RMND5B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RMND5B Gene COMPARTMENTS Subcellular localization image for RMND5B gene
Compartment Confidence
cytosol 2
nucleus 2
endoplasmic reticulum 1
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for RMND5B Gene

Pathways for RMND5B Gene

SuperPathways for RMND5B Gene

No Data Available

Gene Ontology (GO) - Biological Process for RMND5B Gene

None

No data available for Pathways by source for RMND5B Gene

Transcripts for RMND5B Gene

Unigene Clusters for RMND5B Gene

Required for meiotic nuclear division 5 homolog B (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RMND5B Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b · 14c ·
SP1: - - - - - - -
SP2: - - - - - - -
SP3: - -
SP4: - - - - - - -
SP5: - -
SP6: - - - - -
SP7: - - - - - -
SP8: - - - -
SP9: - - - -
SP10: -
SP11:
SP12: -

ExUns: 14d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:

Relevant External Links for RMND5B Gene

GeneLoc Exon Structure for
RMND5B
ECgene alternative splicing isoforms for
RMND5B

Expression for RMND5B Gene

mRNA expression in normal human tissues for RMND5B Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RMND5B Gene

SOURCE GeneReport for Unigene cluster for RMND5B Gene Hs.27222

genes like me logo Genes that share expressions with RMND5B: view

Orthologs for RMND5B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RMND5B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RMND5B 36
  • 99.32 (n)
  • 99.75 (a)
RMND5B 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RMND5B 36
  • 91.77 (n)
  • 95.42 (a)
RMND5B 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RMND5B 36
  • 92.45 (n)
  • 97.2 (a)
RMND5B 37
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rmnd5b 36
  • 89.06 (n)
  • 97.71 (a)
Rmnd5b 16
Rmnd5b 37
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RMND5B 37
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rmnd5b 36
  • 88.89 (n)
  • 98.22 (a)
lizard
(Anolis carolinensis)
Reptilia RMND5B 37
  • 85 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii rmnd5b 36
  • 69.48 (n)
  • 73.15 (a)
rmnd5b 37
  • 73 (a)
OneToOne
zgc73277 36
fruit fly
(Drosophila melanogaster)
Insecta CG3295 37
  • 39 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T07D1.2 36
  • 40.81 (n)
  • 28.97 (a)
T07D1.2 37
  • 22 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RMD5 37
  • 22 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7116 37
  • 48 (a)
OneToMany
Species with no ortholog for RMND5B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RMND5B Gene

ENSEMBL:
Gene Tree for RMND5B (if available)
TreeFam:
Gene Tree for RMND5B (if available)

Paralogs for RMND5B Gene

Paralogs for RMND5B Gene

Selected SIMAP similar genes for RMND5B Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with RMND5B: view

Variants for RMND5B Gene

Sequence variations from dbSNP and Humsavar for RMND5B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs3812071 -- 178,148,265(-) GGAGC(A/G)CAGAG utr-variant-3-prime
rs4490608 -- 178,146,099(+) CCCCT(C/G)TGGTT intron-variant
rs4590193 -- 178,137,345(+) AGTAC(A/G)TAGAA intron-variant
rs4976711 -- 178,138,372(+) ACCTG(C/T)ATCTG intron-variant, utr-variant-5-prime
rs6601217 -- 178,141,838(+) tgact(A/G)tctct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RMND5B Gene

Variant ID Type Subtype PubMed ID
nsv462567 CNV Loss 19166990
nsv471058 CNV Loss 18288195
nsv883190 CNV Loss 21882294
nsv883192 CNV Loss 21882294

Relevant External Links for RMND5B Gene

HapMap Linkage Disequilibrium report
RMND5B

Disorders for RMND5B Gene

No disorders were found for RMND5B Gene.

No data available for UniProtKB/Swiss-Prot for RMND5B Gene

Publications for RMND5B Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. (PMID: 15862967) Pope S.N. … Lee I.R. (J. Steroid Biochem. Mol. Biol. 2005) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for RMND5B Gene

Sources for RMND5B Gene

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