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Aliases for RMND5A Gene

Aliases for RMND5A Gene

  • Required For Meiotic Nuclear Division 5 Homolog A (S. Cerevisiae) 2 3
  • GID Complex Subunit 2 Homolog A 2 3
  • C-Terminal To LisH Motif, 44 KDa 3
  • Protein RMD5 Homolog A 3
  • P44CTLH 3
  • GID2A 3
  • GID2 3
  • CTLH 3
  • RMD5 3

External Ids for RMND5A Gene

Previous GeneCards Identifiers for RMND5A Gene

  • GC02P086947

Summaries for RMND5A Gene

GeneCards Summary for RMND5A Gene

RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with RMND5A include meningoencephalocele. An important paralog of this gene is RMND5B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RMND5A Gene

Genomics for RMND5A Gene

Regulatory Elements for RMND5A Gene

Genomic Location for RMND5A Gene

Start:
86,720,173 bp from pter
End:
86,778,041 bp from pter
Size:
57,869 bases
Orientation:
Plus strand

Genomic View for RMND5A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RMND5A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RMND5A Gene

Proteins for RMND5A Gene

  • Protein details for RMND5A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H871-RMD5A_HUMAN
    Recommended name:
    Protein RMD5 homolog A
    Protein Accession:
    Q9H871
    Secondary Accessions:
    • D6W5M6
    • Q6NTF0
    • Q9H6W5
    • Q9H9H2

    Protein attributes for RMND5A Gene

    Size:
    391 amino acids
    Molecular mass:
    43993 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for RMND5A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RMND5A Gene

Proteomics data for RMND5A Gene at MOPED

Post-translational modifications for RMND5A Gene

  • Ubiquitination at Lys17, Lys218, and Lys365
  • Modification sites at PhosphoSitePlus

Other Protein References for RMND5A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RMND5A Gene

Domains for RMND5A Gene

Suggested Antigen Peptide Sequences for RMND5A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H871

UniProtKB/Swiss-Prot:

RMD5A_HUMAN :
  • Q9H871
Domain:
  • Contains 1 CTLH domain.
  • Contains 1 LisH domain.
genes like me logo Genes that share domains with RMND5A: view

No data available for Gene Families for RMND5A Gene

Function for RMND5A Gene

Gene Ontology (GO) - Molecular Function for RMND5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with RMND5A: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RMND5A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for RMND5A Gene

Localization for RMND5A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RMND5A Gene COMPARTMENTS Subcellular localization image for RMND5A gene
Compartment Confidence
cytosol 3
nucleus 2
cytoskeleton 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RMND5A Gene

Pathways for RMND5A Gene

SuperPathways for RMND5A Gene

No Data Available

Gene Ontology (GO) - Biological Process for RMND5A Gene

None

No data available for Pathways by source for RMND5A Gene

Transcripts for RMND5A Gene

mRNA/cDNA for RMND5A Gene

Unigene Clusters for RMND5A Gene

Required for meiotic nuclear division 5 homolog A (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RMND5A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RMND5A Gene

No ASD Table

Relevant External Links for RMND5A Gene

GeneLoc Exon Structure for
RMND5A
ECgene alternative splicing isoforms for
RMND5A

Expression for RMND5A Gene

mRNA expression in normal human tissues for RMND5A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RMND5A Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (4.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RMND5A Gene

SOURCE GeneReport for Unigene cluster for RMND5A Gene Hs.75277

genes like me logo Genes that share expressions with RMND5A: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for RMND5A Gene

Orthologs for RMND5A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RMND5A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RMND5A 35
  • 99.71 (n)
  • 99.71 (a)
RMND5A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RMND5A 35
  • 94.8 (n)
  • 100 (a)
RMND5A 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RMND5A 35
  • 96.16 (n)
  • 100 (a)
RMND5A 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rmnd5a 35
  • 95.06 (n)
  • 100 (a)
Rmnd5a 16
Rmnd5a 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RMND5A 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RMND5A 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rmnd5a 35
  • 94.03 (n)
  • 100 (a)
chicken
(Gallus gallus)
Aves LOC101751091 35
  • 84.62 (n)
  • 95.99 (a)
lizard
(Anolis carolinensis)
Reptilia RMND5A 36
  • 95 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.6044 35
tropical clawed frog
(Silurana tropicalis)
Amphibia rmnd5a 35
  • 81.33 (n)
  • 93.86 (a)
Str.1465 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011892 35
  • 51.85 (n)
  • 49.05 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG3295 35
  • 52.51 (n)
  • 48.31 (a)
CG3295 36
  • 39 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T07D1.2 36
  • 22 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RMD5 36
  • 23 (a)
OneToMany
RMD5 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G37880 35
  • 48.14 (n)
  • 38.66 (a)
rice
(Oryza sativa)
Liliopsida Os06g0588900 35
  • 48.36 (n)
  • 38.49 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU00898 35
  • 45.3 (n)
  • 41.03 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC29A3.03c 35
  • 44.58 (n)
  • 32.82 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.729 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7116 36
  • 48 (a)
OneToMany
Species with no ortholog for RMND5A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for RMND5A Gene

ENSEMBL:
Gene Tree for RMND5A (if available)
TreeFam:
Gene Tree for RMND5A (if available)

Paralogs for RMND5A Gene

Paralogs for RMND5A Gene

Selected SIMAP similar genes for RMND5A Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for RMND5A Gene

genes like me logo Genes that share paralogs with RMND5A: view

Variants for RMND5A Gene

Sequence variations from dbSNP and Humsavar for RMND5A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1193 -- 86,775,106(-) AAGTC(A/G)CTATG utr-variant-3-prime
rs13297 -- 86,775,583(+) TTGAC(A/G)GTTTT utr-variant-3-prime
rs938486 -- 86,767,596(-) GCTTC(A/G)TTCAC intron-variant
rs1046613 -- 86,774,135(+) TTTTT(G/T)TTTTT utr-variant-3-prime
rs1049457 -- 86,775,905(+) ATCAT(C/T)GCTGA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for RMND5A Gene

Variant ID Type Subtype PubMed ID
nsv10063 CNV Gain 18304495
esv2421358 CNV Deletion 20811451
nsv874472 CNV Gain 21882294
esv25494 CNV Gain 19812545
nsv521780 CNV Loss 19592680
nsv458585 CNV Gain 19166990
nsv819383 CNV Loss 19587683
nsv7316 OTHER Inversion 18451855

Relevant External Links for RMND5A Gene

HapMap Linkage Disequilibrium report
RMND5A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RMND5A Gene

Disorders for RMND5A Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for RMND5A Gene including...

Search for RMND5A Gene in MalaCards »

(1) University of Copenhagen DISEASES for RMND5A Gene

genes like me logo Genes that share disorders with RMND5A: view

No data available for UniProtKB/Swiss-Prot for RMND5A Gene

Publications for RMND5A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. Functional proteomics mapping of a human signaling pathway. (PMID: 15231748) Colland F. … Gauthier J.M. (Genome Res. 2004) 3

Products for RMND5A Gene

Sources for RMND5A Gene

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