Aliases for RMI2 Gene
External Ids for RMI2 Gene
Previous HGNC Symbols for RMI2 Gene
Previous GeneCards Identifiers for RMI2 Gene
RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008]
GeneCards Summary for RMI2 Gene
UniProtKB/Swiss-Prot for RMI2 Gene
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. The complex is therefore essential for the stability, localization, and function of complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.