Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RMDN1 Gene

Aliases for RMDN1 Gene

  • Regulator Of Microtubule Dynamics 1 2 3
  • FAM82B 3 4 6
  • Family With Sequence Similarity 82, Member B 2 3
  • RMD-1 3 4
  • RMD1 3 6
  • Regulator Of Microtubule Dynamics Protein 1 3
  • Microtubule-Associated Protein 3
  • Protein FAM82B 4
  • CGI-90 3
  • HRMD-1 4

External Ids for RMDN1 Gene

Previous Symbols for RMDN1 Gene

  • FAM82B

Summaries for RMDN1 Gene

GeneCards Summary for RMDN1 Gene

RMDN1 (Regulator Of Microtubule Dynamics 1) is a Protein Coding gene. An important paralog of this gene is RMDN2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RMDN1 Gene

Genomics for RMDN1 Gene

Genomic Location for RMDN1 Gene

86,467,398 bp from pter
86,514,357 bp from pter
46,960 bases
Minus strand

Genomic View for RMDN1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RMDN1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RMDN1 Gene

No data available for Regulatory Elements for RMDN1 Gene

Proteins for RMDN1 Gene

  • Protein details for RMDN1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Regulator of microtubule dynamics protein 1
    Protein Accession:
    Secondary Accessions:
    • A9UMZ8
    • B4DNF5
    • B4DZW6
    • B5MC61
    • C9JSC6
    • E7EVI2
    • Q9Y398

    Protein attributes for RMDN1 Gene

    314 amino acids
    Molecular mass:
    35808 Da
    Quaternary structure:
    • Interacts with microtubules.

    Alternative splice isoforms for RMDN1 Gene


neXtProt entry for RMDN1 Gene

Proteomics data for RMDN1 Gene at MOPED

Post-translational modifications for RMDN1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys230, Lys243, and Lys261

No data available for DME Specific Peptides for RMDN1 Gene

Domains for RMDN1 Gene

Protein Domains for RMDN1 Gene



  • Belongs to the RMDN family.:
    • Q96DB5
  • Contains 2 TPR repeats.:
    • Q96DB5
genes like me logo Genes that share domains with RMDN1: view

No data available for Gene Families for RMDN1 Gene

Function for RMDN1 Gene

Phenotypes for RMDN1 Gene

GenomeRNAi human phenotypes for RMDN1:
genes like me logo Genes that share phenotypes with RMDN1: view

miRNA for RMDN1 Gene

miRTarBase miRNAs that target RMDN1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for RMDN1 Gene

Localization for RMDN1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RMDN1 Gene

Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.

Gene Ontology (GO) - Cellular Components for RMDN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IEA --
GO:0005739 mitochondrion IEA --
GO:0005813 centrosome IDA --
GO:0005874 microtubule IEA --
genes like me logo Genes that share ontologies with RMDN1: view

Pathways for RMDN1 Gene

SuperPathways for RMDN1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RMDN1 Gene


No data available for Pathways by source for RMDN1 Gene

Transcripts for RMDN1 Gene

Unigene Clusters for RMDN1 Gene

Regulator of microtubule dynamics 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RMDN1 Gene

No ASD Table

Relevant External Links for RMDN1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RMDN1 Gene

mRNA expression in normal human tissues for RMDN1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RMDN1 Gene

SOURCE GeneReport for Unigene cluster for RMDN1 Gene Hs.145386

genes like me logo Genes that share expressions with RMDN1: view

Orthologs for RMDN1 Gene

This gene was present in the common ancestor of animals.

Orthologs for RMDN1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM82B 36
  • 99.58 (n)
  • 99.36 (a)
RMDN1 37
  • 99 (a)
(Bos Taurus)
Mammalia RMDN1 36
  • 86.94 (n)
  • 86.94 (a)
RMDN1 37
  • 86 (a)
(Canis familiaris)
Mammalia FAM82B 36
  • 88.85 (n)
  • 88.54 (a)
RMDN1 37
  • 88 (a)
(Mus musculus)
Mammalia Rmdn1 36
  • 86.34 (n)
  • 83.93 (a)
Rmdn1 16
Rmdn1 37
  • 84 (a)
(Monodelphis domestica)
Mammalia RMDN1 37
  • 71 (a)
(Ornithorhynchus anatinus)
Mammalia RMDN1 37
  • 71 (a)
(Rattus norvegicus)
Mammalia Rmdn1 36
  • 86.24 (n)
  • 84.52 (a)
(Gallus gallus)
Aves FAM82B 36
  • 72.79 (n)
  • 69.73 (a)
FAM82B 37
  • 66 (a)
(Anolis carolinensis)
Reptilia RMDN1 37
  • 63 (a)
African clawed frog
(Xenopus laevis)
Amphibia MGC64464 36
tropical clawed frog
(Silurana tropicalis)
Amphibia rmdn1 36
  • 62.28 (n)
  • 62.98 (a)
Str.15080 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9264 36
(Danio rerio)
Actinopterygii Dr.12839 36
RMDN1 37
  • 52 (a)
zgc:171674 36
  • 62.34 (n)
  • 59.84 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012364 36
  • 46.19 (n)
  • 39.46 (a)
(Caenorhabditis elegans)
Secernentea F33H2.6 36
  • 49.42 (n)
  • 37.72 (a)
F33H2.6 37
  • 31 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 51 (a)
Species with no ortholog for RMDN1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RMDN1 Gene

Gene Tree for RMDN1 (if available)
Gene Tree for RMDN1 (if available)

Paralogs for RMDN1 Gene

Paralogs for RMDN1 Gene

genes like me logo Genes that share paralogs with RMDN1: view

Variants for RMDN1 Gene

Sequence variations from dbSNP and Humsavar for RMDN1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs13042 -- 86,472,684(+) ttcct(A/G)tgcga utr-variant-3-prime, intron-variant
rs1134059 -- 86,473,159(-) TCAAA(A/C)AAAAA utr-variant-3-prime, intron-variant
rs1135451 -- 86,471,379(-) TAGGG(A/G)TGTAA intron-variant
rs1142528 -- 86,469,071(-) ATTGT(A/G)TTGGG intron-variant
rs3883910 -- 86,503,659(-) ACTCC(A/C)GTGTT intron-variant

Relevant External Links for RMDN1 Gene

HapMap Linkage Disequilibrium report

No data available for Structural Variations from Database of Genomic Variants (DGV) for RMDN1 Gene

Disorders for RMDN1 Gene

No disorders were found for RMDN1 Gene.

No data available for UniProtKB/Swiss-Prot for RMDN1 Gene

Publications for RMDN1 Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. RMD-1, a novel microtubule-associated protein, functions in chromosome segregation in Caenorhabditis elegans. (PMID: 18070910) Oishi K. … Sawa H. (J. Cell Biol. 2007) 3 4
  4. Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma. (PMID: 20000738) Yang X. … Chen X. (J. Proteome Res. 2010) 3
  5. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3

Products for RMDN1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate RMDN1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for RMDN1
    • Block miRNA regulation of RMDN1 using miScript Target Protectors

    Sources for RMDN1 Gene

    Back to Top