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Aliases for RMDN1 Gene

Aliases for RMDN1 Gene

  • Regulator Of Microtubule Dynamics 1 2 3 5
  • Family With Sequence Similarity 82, Member B 2 3
  • FAM82B 3 4
  • RMD-1 3 4
  • Microtubule-Associated Protein 3
  • Protein FAM82B 4
  • CGI-90 3
  • HRMD-1 4
  • RMD1 3

External Ids for RMDN1 Gene

Previous HGNC Symbols for RMDN1 Gene

  • FAM82B

Previous GeneCards Identifiers for RMDN1 Gene

  • GC08M087481

Summaries for RMDN1 Gene

GeneCards Summary for RMDN1 Gene

RMDN1 (Regulator Of Microtubule Dynamics 1) is a Protein Coding gene. An important paralog of this gene is RMDN2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RMDN1 Gene

Genomics for RMDN1 Gene

Genomic Location for RMDN1 Gene

86,467,398 bp from pter
86,514,357 bp from pter
46,960 bases
Minus strand

Genomic View for RMDN1 Gene

Genes around RMDN1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RMDN1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RMDN1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RMDN1 Gene

No data available for Regulatory Elements for RMDN1 Gene

Proteins for RMDN1 Gene

  • Protein details for RMDN1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Regulator of microtubule dynamics protein 1
    Protein Accession:
    Secondary Accessions:
    • A9UMZ8
    • B4DNF5
    • B4DZW6
    • B5MC61
    • C9JSC6
    • E7EVI2
    • Q9Y398

    Protein attributes for RMDN1 Gene

    314 amino acids
    Molecular mass:
    35808 Da
    Quaternary structure:
    • Interacts with microtubules.

    Alternative splice isoforms for RMDN1 Gene


neXtProt entry for RMDN1 Gene

Proteomics data for RMDN1 Gene at MOPED

Post-translational modifications for RMDN1 Gene

  • Ubiquitination at Lys 230, Lys 243, and Lys 261
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for RMDN1 Gene

Domains & Families for RMDN1 Gene

Protein Domains for RMDN1 Gene


Suggested Antigen Peptide Sequences for RMDN1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the RMDN family.
  • Contains 2 TPR repeats.
  • Belongs to the RMDN family.
  • Contains 2 TPR repeats.
genes like me logo Genes that share domains with RMDN1: view

No data available for Gene Families for RMDN1 Gene

Function for RMDN1 Gene

genes like me logo Genes that share phenotypes with RMDN1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RMDN1 Gene

Localization for RMDN1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RMDN1 Gene

Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.

Gene Ontology (GO) - Cellular Components for RMDN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IEA --
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with RMDN1: view

No data available for Subcellular locations from COMPARTMENTS for RMDN1 Gene

Pathways & Interactions for RMDN1 Gene

SuperPathways for RMDN1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RMDN1 Gene


No data available for Pathways by source and SIGNOR curated interactions for RMDN1 Gene

Drugs & Compounds for RMDN1 Gene

No Compound Related Data Available

Transcripts for RMDN1 Gene

Unigene Clusters for RMDN1 Gene

Regulator of microtubule dynamics 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RMDN1 Gene

No ASD Table

Relevant External Links for RMDN1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RMDN1 Gene

mRNA expression in normal human tissues for RMDN1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for RMDN1 Gene

This gene is overexpressed in Heart (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RMDN1 Gene

SOURCE GeneReport for Unigene cluster for RMDN1 Gene Hs.145386

genes like me logo Genes that share expression patterns with RMDN1: view

Protein tissue co-expression partners for RMDN1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RMDN1 Gene

Orthologs for RMDN1 Gene

This gene was present in the common ancestor of animals.

Orthologs for RMDN1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RMDN1 35
  • 86.94 (n)
  • 86.94 (a)
RMDN1 36
  • 86 (a)
(Canis familiaris)
Mammalia FAM82B 35
  • 88.85 (n)
  • 88.54 (a)
RMDN1 36
  • 88 (a)
(Mus musculus)
Mammalia Rmdn1 35
  • 86.34 (n)
  • 83.93 (a)
Rmdn1 16
Rmdn1 36
  • 84 (a)
(Pan troglodytes)
Mammalia FAM82B 35
  • 99.58 (n)
  • 99.36 (a)
RMDN1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Rmdn1 35
  • 86.24 (n)
  • 84.52 (a)
(Monodelphis domestica)
Mammalia RMDN1 36
  • 71 (a)
(Ornithorhynchus anatinus)
Mammalia RMDN1 36
  • 71 (a)
(Gallus gallus)
Aves FAM82B 35
  • 72.79 (n)
  • 69.73 (a)
FAM82B 36
  • 66 (a)
(Anolis carolinensis)
Reptilia RMDN1 36
  • 63 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rmdn1 35
  • 62.28 (n)
  • 62.98 (a)
Str.15080 35
African clawed frog
(Xenopus laevis)
Amphibia MGC64464 35
(Danio rerio)
Actinopterygii Dr.12839 35
zgc:171674 35
  • 62.34 (n)
  • 59.84 (a)
RMDN1 36
  • 52 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9264 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012364 35
  • 46.19 (n)
  • 39.46 (a)
(Caenorhabditis elegans)
Secernentea F33H2.6 35
  • 49.42 (n)
  • 37.72 (a)
F33H2.6 36
  • 31 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 51 (a)
Species with no ortholog for RMDN1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RMDN1 Gene

Gene Tree for RMDN1 (if available)
Gene Tree for RMDN1 (if available)

Paralogs for RMDN1 Gene

Paralogs for RMDN1 Gene

genes like me logo Genes that share paralogs with RMDN1: view

Variants for RMDN1 Gene

Sequence variations from dbSNP and Humsavar for RMDN1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs6980476 - 86,507,086(+) CCTCT(G/T)TTGAA nc-transcript-variant, reference, missense
rs13042 -- 86,472,684(+) ttcct(A/G)tgcga intron-variant, utr-variant-3-prime
rs1134059 -- 86,473,159(-) TCAAA(A/C)AAAAA intron-variant, utr-variant-3-prime
rs1135451 -- 86,471,379(-) TAGGG(A/G)TGTAA intron-variant
rs1142528 -- 86,469,071(-) ATTGT(A/G)TTGGG intron-variant, nc-transcript-variant, downstream-variant-500B

Variation tolerance for RMDN1 Gene

Residual Variation Intolerance Score: 74.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.79; 79.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RMDN1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RMDN1 Gene

Disorders for RMDN1 Gene

Relevant External Links for RMDN1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RMDN1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RMDN1 Gene

Publications for RMDN1 Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4 67
  2. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  3. MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. (PMID: 22114354) Alkhaja A.K. … Deckers M. (Mol. Biol. Cell 2012) 3
  4. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. (PMID: 23284306) Xie L. … Green M.R. (PLoS Genet. 2012) 3
  5. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. (PMID: 21048031) Casabonne D. … de Sanjose S. (Haematologica 2011) 3

Products for RMDN1 Gene

Sources for RMDN1 Gene

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