RLIM Gene
protein-coding GIFtS: 50
GCID: GC0XM073803
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ring finger protein, LIM domain interacting(Previous name: ring finger protein 12 )
(Previous symbol: RNF12)
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Aliases
for RLIM gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ring Finger Protein, LIM Domain Interacting1 2 | | MGC151611 | | RNF121 2 3 5 | | E3 Ubiquitin-Protein Ligase RLIM2 | | RING Finger Protein 121 2 3 | | E3 Ubiquitin-Protein Ligase RNF122 | | NY-REN-431 2 | | Ring Zinc Finger LIM Domain Binding Protein2 | | Renal Carcinoma Antigen NY-REN-432 3 | | Ring Zinc Finger Protein NY-REN-43antigen2 | | R-LIM2 3 | | EC 6.3.2.-3 | | LIM Domain-Interacting RING Finger Protein2 3 | | EC 6.3.28 | | RING Finger LIM Domain-Binding Protein2 3 | | |
Export aliases for RLIM gene to outside databasesPrevious GC identifers: GC0XM073726 GC0XM067438 |
Summaries
for RLIM gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RLIM:
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin proteinligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. Thisprotein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively splicedvariants, encoding the same protein, have been identified. (provided by RefSeq, Feb 2009)
UniProtKB/Swiss-Prot: RNF12_HUMAN, Q9NVW2Function: E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors bymediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating therecruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM.Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1.By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, astochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encodedgenes in somatic cells of female placental mammals
Gene Wiki entry for RLIM (RNF12)
|
Genomic Views
for RLIM gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011669.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RLIM gene promoter:
HOXA9 Bach1 LHX3b/Lhx3b POU3F1 Meis-1b FOXL1 Max LHX3a/Lhx3a c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for RLIM
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RLIM |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq13-q21 Ensembl cytogenetic band: Xq13.2 HGNC cytogenetic band: Xq13-q21RLIM Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM073803: view genomic region
(about GC identifiers)
Start:
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73,802,811 bp from pter |
End:
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73,834,461 bp from pter |
Size:
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31,651 bases |
Orientation:
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minus strand |
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Proteins
for RLIM gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RNF12_HUMAN, Q9NVW2 (See
protein sequence)Recommended Name: E3 ubiquitin-protein ligase RLIM Size: 624 amino acids; 68549 Da
Subunit: Interacts with LIM/homeobox factors such as LHX3. Interacts with LDB1, LDB2 and SIN3A (By similarity).Interacts with LIMK1 (By similarity). Interacts (via N-terminus) with TERF1. Interacts (via C-terminus) with ESR1
Subcellular location: Nucleus
Miscellaneous: Acts as a positive coregulator of ESR1-mediated transcription in breast cancer cells
Sequence caution: Sequence=AAD42875.1; Type=Frameshift; Positions=134, 142;
Secondary accessions: D3DTE0 Q96D38 Q9Y598Explore the universe of human proteins at neXtProt for RLIM: NX_Q9NVW2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NVW2
4/10 DME Specific Peptides for RLIM (Q9NVW2) (see all 10)
RLIM Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_057204.2 NP_899196.1
ENSEMBL proteins: ENSP00000328059 ENSP00000253571
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
RLIM for ontologies About GeneDecksing
RLIM Antibody Products:
Assay Products for RLIM: |
Protein
Domains /
Families
for RLIM gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RLIM for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NVW2ProtoNet protein and cluster: Q9NVW2 1 Blocks protein family: IPB001841 Zn-finger
UniProtKB/Swiss-Prot: RNF12_HUMAN, Q9NVW2Similarity: Belongs to the RNF12 familySimilarity: Contains 1 RING-type zinc finger |
Function
for RLIM gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RNF12_HUMAN, Q9NVW2Function: E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors bymediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating therecruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM.Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1.By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, astochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encodedgenes in somatic cells of female placental mammalsEnzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RLIM (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RLIM (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for RLIM | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RLIM |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RLIM |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RLIM for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Rlimtm1.2Inba for RLIM
5 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Rlim):
RLIM for phenotypes About GeneDecksing
|
Pathways & Interactions
for RLIM gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
UniProtKB/Swiss-Prot: RNF12_HUMAN, Q9NVW2Pathway: Protein modification; protein ubiquitinationInteractions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RLIM
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/29 Interacting proteins for RLIM (Q9NVW22, 3 ENSP000002535714) via UniProtKB, MINT, STRING, and/or I2D (see all 29) About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IEA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006511 | ubiquitin-dependent protein catabolic process |
ISS | -- | | GO:0016567 | protein ubiquitination |
ISS | -- | | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity |
IEA | -- |
RLIM for ontologies About GeneDecksing
|
Drugs & Compounds
for RLIM gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RLIM
Search CenterWatch for drugs/clinical trials and news about RLIM / RNF12
|
Transcripts
for RLIM gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RLIM gene (2 alternative transcripts): NM_016120.3 NM_183353.2 Unigene Cluster for RLIM: Ring finger protein, LIM domain interacting Hs.653288 [show with all ESTs]Unigene Representative Sequence: NM_1833532 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000332687(uc004ebu.3 uc004ebw.3) ENST00000349225
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RLIM (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RLIM (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RLIM (NM_183353) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RLIM | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RLIM |
Additional cDNA sequence: AF086467.1 AF155109.1 AK001334.1 AK098789.1 AK123088.1 AK124877.1 AK127880.1 AK314760.1 BC013357.2 BX648613.1 24/25 DOTS entries (see all 25): DT.410275 DT.300473 DT.100642596 DT.95267608 DT.92470838 DT.91801712 DT.100700590 DT.100700601 DT.100043224 DT.100700595 DT.92470903 DT.121319026 DT.95267607 DT.102836544 DT.92470896 DT.97869208 DT.86839552 DT.100040311 DT.100700578 DT.100852698 DT.101963232 DT.121466365 DT.40122970 DT.91815156 24/238 AceView cDNA sequences (see all 238): BX116090 NM_183353 AW418948 NM_016120 BQ930350 BU521294 AK124877 BM850296 AA516103 CA416139 BM471060 BQ005658 BM981885 BX111253 BX483893 AI590361 AA400980 BI962780 BM769057 AK123088 W81445 AA932882 AI343614 AA405476
GeneLoc Exon Structure
|
Expression
for RLIM gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RLIM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RLIM Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RLIM
SOURCE GeneReport for Unigene cluster: Hs.653288
UniProtKB/Swiss-Prot: RNF12_HUMAN, Q9NVW2Tissue specificity: Expressed in many tissues
SABiosciences Custom PCR Arrays for RLIM
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RLIM
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RLIM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RLIM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RLIM | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RLIM |
Orthologs
for RLIM gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RLIM gene from 6/16 species (see all 16) About this table
ENSEMBL Gene Tree for RLIM (if available)
TreeFam Gene Tree for RLIM (if available) |
Paralogs
for RLIM gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RLIM gene
- RNF62 RNF112 RNF1652 RNF382 RNF442 RNF1112
2 SIMAP similar genes for RLIM using alignment to 2 protein entries: RNF12_HUMAN (see all proteins):RNF6 DKFZp686P0776
RLIM for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for RLIM
PGOHUM00000247113 PGOHUM00000244148
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Genomic Variants
for RLIM gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RLIM (73802811 - 73834461 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RLIM: --
Locus Specific Mutation Databases (LSDB): RLIM
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RLIM |
|
Disorders
/ Diseases
for RLIM gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RLIM for disorders About GeneDecksing
OMIM gene information: 300379
OMIM disorders: --
7  diseases for RLIM: About MalaCardsrenal carcinoma carcinoma smallpox renal cell carcinoma
pertussis breast cancer leukemia
1 disease from the University of Copenhagen DISEASES database for RLIM:Pertussis Export disorders for RLIM gene to outside databases
|
Publications
for RLIM gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RLIM gene, integrated from 9 sources (see all 31):
(articles sorted by number of sources associating them with RLIM) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479)1, 2, 3 Scanlan M.J....Old L.J. (1999)
- Regulation of estrogen-dependent transcription by the LIM cofactors CLIM and RLIM in breast cancer. (PubMed id 19117995)1, 2, 9 Johnsen S.A.... Bach I. (2009)
- Functional characterization of the gene encoding RLIM, the corepressor of LIM homeodomain transcription factors. (PubMed id 11013082)1, 2, 9 Ostendorff H.P.... Bach I. (2000)
- Ubiquitin ligase RLIM modulates telomere length homeostasis through a proteolysis of TRF1. (PubMed id 19164295)1, 2 Her Y.R. and Chung I.K. (2009)
- RNF12 is an X-encoded dose-dependent activator of X chromosome inactivation. (PubMed id 19945382)1, 2 Jonkers I.... Gribnau J. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors. (PubMed id 11882901)1, 9 Ostendorff H.P....Bach I. (2002)
- RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. (PubMed id 10431247)1, 9 Bach I....Rosenfeld M.G. (1999)
- Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
- RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation. (PubMed id 22596162)1 Gontan C....Gribnau J. (2012)
|
External Searches for RLIM gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RLIM gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RLIM gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RLIM gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RLIM | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RLIM gene:
Search GeneIP for patents involving RLIM
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RLIM gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RLIM | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RLIM | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RLIM | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RLIM | | OriGene 3'-UTR Clone for RLIM | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RLIM | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RLIM | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RLIM | | OriGene Custom Protein Services for RLIM | | | OriGene Custom Immunoassay Development | | |
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 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RLIM | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RLIM | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RLIM | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RLIM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RLIM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RLIM |
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 |  |  |  | |
| | | | Search Tocris compounds for RLIM |
| |  |  |  |  | | | | |
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 | | | RLIM Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RLIM |
|  |  |  | | | | ThermoFisher Antibodies for RLIM |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RLIM |
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