Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RLF Gene

protein-coding   GIFtS: 53
GCID: GC01P040627

rearranged L-myc fusion

(Previous name: rearranged L-myc fusion sequence )
 Explore 5 diseases affiliated with
RLF via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RLF    

Aliases
for RLF gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Rearranged L-Myc Fusion1 2     Zn-15L1
ZNF292L1 2     ZN-15L2
Rearranged L-Myc Fusion Sequence1 2     Zinc Finger Protein Rlf2
Rearranged L-Myc Fusion Gene Protein2 3     Zn-15 Related2
Zn-15-Related Protein2 3     

External Ids:    HGNC: 100251   Entrez Gene: 60182   Ensembl: ENSG000001170007   OMIM: 1806105   UniProtKB: Q131293   

Export aliases for RLF gene to outside databases

Previous GC identifers: GC01P040661 GC01P039630 GC01P040090 GC01P040040 GC01P040296 GC01P040399 GC01P038745


Summaries
for RLF gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: RLF_HUMAN, Q13129
Function: May be involved in transcriptional regulation

Gene Wiki entry for RLF


Genomic Views
for RLF gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RLF gene promoter:
         AhR   ATF-2   NCX/Ncx   XBP-1   Arnt   CREB   RORalpha1   CRE-BP1   COMP1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RLF promoter sequence
   Search SABiosciences Chromatin IP Primers for RLF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RLF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p32

RLF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RLF gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P040627:  view genomic region     (about GC identifiers)

Start:
 40,627,041 bp from pter      End:
 40,706,593 bp from pter
Size:
 79,553 bases      Orientation:
 plus strand

Proteins
for RLF gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RLF_HUMAN, Q13129 (See protein sequence)
Recommended Name: Zinc finger protein Rlf  
Size: 1914 amino acids; 217953 Da
Subunit: Interacts with RIT1 and RIT2 (By similarity)
Subcellular location: Nucleus (Probable)
Miscellaneous: In some small cell lung carcinoma (SCLC) cell lines, there is an intrachromosomal rearrangements at 1p32
fusing the first exon of the RLF gene with L-myc
Secondary accessions: Q14CQ1 Q9NU60

Explore the universe of human proteins at neXtProt for RLF: NX_Q13129

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13129

    • RLF Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036553.2  
    ENSEMBL proteins: 
     ENSP00000361857  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for RLF 
    GenScript Custom Purified and Recombinant Proteins Services for RLF
    Novus Biologicals RLF Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RLF

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC8545128


    RLF for ontologies           About GeneDecksing



    RLF Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RLF 
    GenScript Custom Superior Antibodies Services for RLF
    Novus Biologicals RLF Antibodies
    Search for Antibodies for RLF at Abcam  
    Uscn Antibodies for RLF
    Search ThermoFisher Antibodies for RLF

    Assay Products for RLF: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RLF
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for RLF

    Protein Domains /
    Families
    for RLF gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RLF for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q13129

    ProtoNet protein and cluster: Q13129

    1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: RLF_HUMAN, Q13129
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 14 C2H2-type zinc fingers


    Function
    for RLF gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: RLF_HUMAN, Q13129
    Function: May be involved in transcriptional regulation

         Genatlas biochemistry entry for RLF:
    rearranged l-myc fusion gene,in small cell lung carcinoma

    miRNA
    Products:            		 OriGene 3'-UTR Clone: RLF
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RLF
    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate RLF (see all 27):
    hsa-miR-142-3p hsa-miR-181c hsa-miR-29a hsa-miR-29c hsa-miR-764 hsa-miR-20b* hsa-miR-373* hsa-miR-1262
    SwitchGear 3'UTR luciferase reporter plasmid: RLF 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RLF (see all 4)
    OriGene shRNA RFP: RLF
    OriGene siRNA: RLF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RLF

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RLF

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RLF (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RLF
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: RLF (NM_004491)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RLF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RLF 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for RLF
    Search LifeMap BioReagents cell lines for RLF

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RLF

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding NAS8545128
    GO:0005515protein binding IPI10545207
    GO:0008270zinc ion binding IEA--


    RLF for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for RLF:
     Increased S DNA content  Synthetic lethal with Ras  Synthetic lethal with c-Myc af 


    Pathways & Interactions
    for RLF gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RLF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/14 Interacting proteins for RLF (Q131291, 2, 3 ENSP000003618574) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRPF40AO754002, 3MINT-61878 I2D: score=3 
    RIT1Q929631, 3, ENSP000003573064EBI-958266,EBI-365845 I2D: score=4 STRING: ENSP00000357306
    GCH1P307933, ENSP000003788904I2D: score=3 STRING: ENSP00000378890
    CNKSR2Q8WXI23, ENSP000003688244I2D: score=1 STRING: ENSP00000368824
    RIT2Q995783, ENSP000003218054I2D: score=3 STRING: ENSP00000321805
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent NAS8545128
    GO:0009294DNA mediated transformation NAS8545128
    GO:0015074DNA integration IDA1851085
    GO:0045893positive regulation of transcription, DNA-dependent ISS8545128


    RLF for ontologies           About GeneDecksing



    Drugs & Compounds
    for RLF gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RLF
    Search CenterWatch for drugs/clinical trials and news about RLF 

    Transcripts
    for RLF gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RLF gene: 
    NM_012421.3  

    Unigene Cluster for RLF:

    Rearranged L-myc fusion
    Hs.205627  [show with all ESTs]
    Unigene Representative Sequence: NM_012421
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372771(uc001cfc.4 uc001cfd.4) ENST00000487606

    miRNA
    Products:             		 OriGene 3'-UTR Clone: RLF
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RLF
    8/27 QIAGEN miScript miRNA Assays for microRNAs that regulate RLF (see all 27):
    hsa-miR-142-3p hsa-miR-181c hsa-miR-29a hsa-miR-29c hsa-miR-764 hsa-miR-20b* hsa-miR-373* hsa-miR-1262
    SwitchGear 3'UTR luciferase reporter plasmid: RLF 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RLF (see all 4)
    OriGene shRNA RFP: RLF
    OriGene siRNA: RLF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RLF
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RLF (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RLF
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: RLF (NM_004491)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RLF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RLF 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RLF
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RLF
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RLF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RLF

    Additional cDNA sequence: 

    AK307662.1 BC113666.1 BX537979.1 U22377.1 X58480.1 

    9 DOTS entries:

    DT.214756  DT.97800159  DT.95363715  DT.121437600  DT.121437615  DT.121437621  DT.121437628  DT.95262154 
    DT.100754512 

    24/118 AceView cDNA sequences (see all 118):

    CB163941 AW102775 F12163 BM698782 AW274998 BM669568 BM542854 BM712271 
    BP339286 F11598 AI803292 AW383138 AW196684 AI826273 BU678115 BM806992 
    BX956701 CB126178 AU130403 BX105264 AW383178 AI765591 AW572667 AA173500 

    GeneLoc Exon Structure


    Expression
    for RLF gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RLF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATTGTATATG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RLF expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Reproductive SystemEarly GonadTestis Somatic CellsTestis
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RLF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RLF

    SOURCE GeneReport for Unigene cluster: Hs.205627

    UniProtKB/Swiss-Prot: RLF_HUMAN, Q13129
    Tissue specificity: Widely expressed in fetal and adult tissues

        SABiosciences Custom PCR Arrays for RLF
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RLF
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RLF
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RLF
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RLF
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RLF

    Orthologs
    for RLF gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for RLF gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves RLF6
    		 Uncharacterized protein
    		 63(a)
    		 1 ↔ 1
    		 23(1704306-1733624)
    lizard
    (Anolis carolinensis)    		 Reptilia RLF6
    		 --
    		 58(a)
    		 1 ↔ 1
    		 GL343276.1(1767463-1785593)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.305672 Xenopus laevis transcribed sequence with moderate similarity more 74.78(n)    48046441 
    zebrafish
    (Danio rerio)    		 Actinopterygii rlf1 rearranged L-myc fusion 48.69(n)
    38.88(a)    		   562452  XM_685832.5  XP_690924.5 


    ENSEMBL Gene Tree for RLF (if available)
    TreeFam Gene Tree for RLF (if available) 

    Paralogs
    for RLF gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RLF gene
    ZNF6542  ZNF2922  ENSG000002297292  
    1 SIMAP similar gene for RLF using alignment to 1 protein entry:     RLF_HUMAN:
    ZNF808

    RLF for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for RLF
    PGOHUM00000245666 PGOHUM00000235409


    Genomic Variants
    for RLF gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1363 NCBI SNPs in RLF are shown (see all 1363)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1480247761,2
    		--40625083(+) CCACAG/TCTTTG 1 -- us2k10--------
    rs1923944331,2
    		--40625225(+) GGTCTC/TGAACT 1 -- us2k10--------
    rs75188421,2
    		C,--40625252(+) CCTCCG/CGCCTT 1 -- us2k13Minor allele frequency- C:0.23NA WA 122
    rs1417267781,2
    		--40625358(+) ACTATC/TTGTTT 1 -- us2k10--------
    rs352528151,2
    		C,--40625373(+) GTTTG-/TTTTTT 1 -- us2k10--------
    rs1848794461,2
    		--40625704(+) TATGGC/TTGGGC 1 -- us2k10--------
    rs1505699251,2
    		--40625738(+) CAGCAA/CTTTGG 1 -- us2k10--------
    rs1508628391,2
    		C,--40626095(+) TTAAT-/ACAGTCA 1 -- us2k10--------
    rs44575631,2
    		--40626168(+) GGCGCG/AGTGGC 1 -- us2k12Minor allele frequency- A:0.25NA 4
    rs1123237541,2
    		C,--40626345(+) GAGGCAGG/-AGAAT 1 -- us2k11Minor allele frequency- -:0.50CSA 2

    HapMap Linkage Disequilibrium report for RLF (40627041 - 40706593 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for RLF
         2 CNVs: 4219 3289

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RLF
    DNA2.0 Custom Variant and Variant Library Synthesis for RLF

    Disorders / Diseases
    for RLF gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RLF for disorders           About GeneDecksing

    OMIM gene information: 180610    OMIM disorders: --

    5 diseases for RLF:    About MalaCards
    retinopathy of prematurity    cryptorchidism    lung carcinoma    lung cancer
    carcinoma

    2 Novoseek disease relationships for RLF gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cancer lung 39.9 3 1312699 (2), 1649386 (1)
    tumors 0 2 1312699 (2)


    Export disorders for RLF gene to outside databases

    Publications
    for RLF gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RLF gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with RLF)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein. (PubMed id 8545128)1, 2, 9 Makela T.P.... Alitalo K. (1995)
    2. Intrachromosomal rearrangements fusing L-myc and rlf in small-cell lung cancer. (PubMed id 1649386)1, 3, 9 Makela T.P....Alitalo K. (1991)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    10. A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions. (PubMed id 16696853)1 Swick L. and Kapatos G. (2006)

    External Searches for RLF gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing RLF gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6018 HGNC: 10025 AceView: RLF Ensembl:ENSG00000117000 euGenes: HUgn6018
    ECgene: RLF H-InvDB: RLF

    Other Databases showing RLF gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RLF gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RLF Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RLF Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for RLF gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RLF gene:
    Search GeneIP for patents involving RLF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for RLF gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for RLF  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RLF   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RLF  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for RLF   OriGene 3'-UTR Clone for RLF  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RLF   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RLF  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RLF   OriGene Custom Protein Services for RLF  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RLF
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RLF
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RLF
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RLF
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RLF
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RLF
     GenScript Custom Purified and Recombinant Proteins Services for RLF GenScript cDNA clones with any tag delivered in your preferred vector for RLF
     GenScript Custom Assay Services for RLF GenScript Custom Superior Antibodies Services for RLF
     GenScript Custom overexpressing Cell Line Services for RLF CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in RLF promoter
     Search Chromatin IP Primers for RLF
     RT2 qPCR Primer Assay in human, mouse, rat RLF
     Search GNC Networks for RLF
     SABiosciences Custom PCR Arrays for RLF
     Search Tocris compounds for RLF
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     RLF antibodies
     RLF proteins
     Search for Antibodies for RLF at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for RLF
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     RLF Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for RLF
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RLF
     SwitchGear 3'UTR luciferase reporter plasmids for RLF
     SwitchGear Promoter luciferase reporter plasmids for RLF
     Search ThermoFisher Antibodies for RLF
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RLF
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      RLF gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4