Aliases for RITA1 Gene
External Ids for RITA1 Gene
Previous Symbols for RITA1 Gene
GeneCards Summary for RITA1 Gene
RITA1 (RBPJ Interacting And Tubulin Associated 1) is a Protein Coding gene.
UniProtKB/Swiss-Prot for RITA1 Gene
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.