Aliases for RIT2 Gene
External Ids for RIT2 Gene
Previous HGNC Symbols for RIT2 Gene
Previous GeneCards Identifiers for RIT2 Gene
RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RIT2 Gene
RIT2 (Ras Like Without CAAX 2) is a Protein Coding gene. Diseases associated with RIT2 include Ehrlichiosis and Parkinson Disease Susceptibility. Among its related pathways are RET signaling and Neurotrophic factor-mediated Trk receptor signaling. GO annotations related to this gene include GTP binding and calmodulin binding. An important paralog of this gene is RIT1.
UniProtKB/Swiss-Prot for RIT2 Gene
Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.