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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RIOK3 Gene

protein-coding   GIFtS: 55
GCID: GC18P021032

RIO Kinase 3

(Previous names: sudD (suppressor of bimD6, Aspergillus nidulans) homolog,...)
(Previous symbol: SUDD)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RIO Kinase 31 2 3     Homolog Of The Aspergillus Nidulans SudD Gene Product2
SUDD1 2 3 5     Serine/Threonine-Protein Kinase RIO32
SudD (Suppressor Of BimD6, Aspergillus Nidulans) Homolog1 2     SudD Suppressor Of Aspergillus Nidulans BimD6 Homolog2
SudD Homolog2 3     SudD Suppressor Of BimD6 Homolog2
RIO Kinase 3 (Yeast)1     EC 2.7.11.13

External Ids:    HGNC: 114511   Entrez Gene: 87802   Ensembl: ENSG000001017827   OMIM: 6035795   UniProtKB: O147303   

Export aliases for RIOK3 gene to outside databases

Previous GC identifers: GC18P020920 GC18P019285 GC18P019287 GC18P017887


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RIOK3 Gene:
This gene was identified by the similarity of its product to the Aspergillus nidulans SUDD protein, an extragenic
suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a
restrictive temperature. The specific function of this gene has not yet been determined. (provided by RefSeq, Jul
2008)

GeneCards Summary for RIOK3 Gene: 
RIOK3 (RIO kinase 3) is a protein-coding gene. Diseases associated with RIOK3 include alcoholism, and melanoma. GO annotations related to this gene include protein serine/threonine kinase activity and ATP binding. An important paralog of this gene is RIOK1.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NT_010966.14  NC_018929.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RIOK3 gene promoter:
         NF-YA   NF-YC   CUTL1   CBF-C   NF-YB   FOXO4   SEF-1 (1)   CP1A   CP1C   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRIOK3 promoter sequence
   Search SABiosciences Chromatin IP Primers for RIOK3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RIOK3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q11.2   Ensembl cytogenetic band:  18q11.2   HGNC cytogenetic band: 18q11.2

RIOK3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RIOK3 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P021032:  view genomic region     (about GC identifiers)

Start:
21,032,787 bp from pter      End:
21,066,567 bp from pter
Size:
33,781 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RIOK3_HUMAN, O14730 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase RIO3  
Size: 519 amino acids; 59093 Da
Secondary accessions: Q8IXN9
Alternative splicing: 2 isoforms:  O14730-1   O14730-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RIOK3: NX_O14730

Explore proteomics data for RIOK3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O14730

  • RIOK3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RIOK3 Protein Expression
    REFSEQ proteins: NP_003822.2  
    ENSEMBL proteins: 
     ENSP00000341874   ENSP00000463660   ENSP00000462548   ENSP00000463791   ENSP00000463644  

    Human Recombinant Protein Products for RIOK3: 
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    Novus Biologicals RIOK3 Proteins
    Novus Biologicals RIOK3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RIOK3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----

    RIOK3 for ontologies           About GeneDecksing



    RIOK3 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: RIO kinase 3 (yeast) 
    RIO3 subfamily

    5 InterPro protein domains:
     IPR000687 RIO_kinase
     IPR011009 Kinase-like_dom
     IPR018935 RIO_kinase_CS
     IPR017406 Ser/Thr_kinase_Rio3
     IPR018934 RIO-like_kinase

    Graphical View of Domain Structure for InterPro Entry O14730

    ProtoNet protein and cluster: O14730

    1 Blocks protein domain: IPB000687 Protein of unknown function RIO1

    UniProtKB/Swiss-Prot: RIOK3_HUMAN, O14730
    Similarity: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family
    Similarity: Contains 1 protein kinase domain


    RIOK3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RIOK3_HUMAN, O14730
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Enzyme Number (IUBMB): EC 2.7.11.11

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    RIOK3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RIOK3:
     Decreased focal adhesion (FA)   Decreased substrate adherent c 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RIOK3 
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    miRNA
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    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate RIOK3 (see all 33):
    hsa-let-7d hsa-miR-29a hsa-miR-30d hsa-let-7g hsa-miR-30a hsa-let-7a hsa-miR-186 hsa-miR-203
    SwitchGear 3'UTR luciferase reporter plasmidRIOK3 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RIOK3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RIOK3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/31 Interacting proteins for RIOK3 (O147301, 3 ENSP000003418744) via UniProtKB, MINT, STRING, and/or I2D (see all 31)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM3P621583, ENSP000002912954I2D: score=2 STRING: ENSP00000291295
    CALM1P621583, ENSP000003494674I2D: score=2 STRING: ENSP00000349467
    CALM2P621583I2D: score=2 
    FBLP220873, ENSP000002218014I2D: score=2 STRING: ENSP00000221801
    PSMB1P206183, ENSP000002621934I2D: score=2 STRING: ENSP00000262193
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007059chromosome segregation TAS9602165
    GO:0009103lipopolysaccharide biosynthetic process ----

    RIOK3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RIOK3

    2 HMDB Compounds for RIOK3    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--

    Search CenterWatch for drugs/clinical trials and news about RIOK3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RIOK3 gene (2 alternative transcripts): 
    NM_003831.3  NM_145906.1  

    Unigene Cluster for RIOK3:

    RIO kinase 3
    Hs.728452  [show with all ESTs]
    Unigene Representative Sequence: NM_003831
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000339486(uc002kui.4 uc010dls.3 uc010xas.2 uc010xat.2)
    ENST00000584960 ENST00000581585 ENST00000584052 ENST00000581302 ENST00000577501
    ENST00000584992 ENST00000584130 ENST00000581339 ENST00000577250 ENST00000581220

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RIOK3
    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate RIOK3 (see all 33):
    hsa-let-7d hsa-miR-29a hsa-miR-30d hsa-let-7g hsa-miR-30a hsa-let-7a hsa-miR-186 hsa-miR-203
    SwitchGear 3'UTR luciferase reporter plasmidRIOK3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RIOK3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RIOK3
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    OriGene clones in human, mouse for RIOK3 (see all 9)
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    GenScript: all cDNA clones in your preferred vector: RIOK3 (NM_003831)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RIOK3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RIOK3
    Sirion Biotech Customized lentivirus for stable overexpression of RIOK3 
                         Customized lentivirus expression plasmids for stable overexpression of RIOK3 
    Primer
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    OriGene qPCR primer pairs and template standards for RIOK3
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RIOK3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RIOK3

    Additional mRNA sequence: 

    AF013591.1 AK057292.1 AK303938.1 AK304571.1 AK310783.1 BC039729.1 

    18 DOTS entries:

    DT.455721  DT.91768972  DT.92410144  DT.91768944  DT.121085788  DT.100813622  DT.75198847  DT.97785607 
    DT.121085755  DT.121085760  DT.121085763  DT.121085773  DT.40196089  DT.86840335  DT.91768946  DT.95370701 
    DT.107958  DT.75106689 

    24/236 AceView cDNA sequences (see all 236):

    AA489485 AU137473 AU142572 BQ082309 AW088631 BQ183300 AI925065 AW511310 
    AL047881 AA732512 BM721795 H12856 CB242096 BC039729 BU187701 AI911181 
    CR610942 AA760632 AK057292 CB135939 AI803141 BE017970 NM_003831 BC028360 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for RIOK3 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b
    SP1:                                -     -           -                                                                                             
    SP2:                                -     -           -                                                                       -                     
    SP3:                                                                                -           -                                                   
    SP4:                                                                                                                                                
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for RIOK3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RIOK3 expression in normal human tissues (normalized intensities)      RIOK3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTCCTATTA
    RIOK3 Expression
    About this image


    RIOK3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Blood (Cardiovascular System)    fully expand to see all 3 entries
             Double Positive Thymocytes Thymus
             umbilical cord reticulocytes   
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Umbilical Cord (Extraembryonic Tissues)
             umbilical cord reticulocytes   
     
     Eye (Sensory Organs)
             Retina
     
     Esophagus (Gastrointestinal Tract)

    See RIOK3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RIOK3

    SOURCE GeneReport for Unigene cluster: Hs.728452

    UniProtKB/Swiss-Prot: RIOK3_HUMAN, O14730
    Tissue specificity: Widely expressed

        SABiosciences Custom PCR Arrays for RIOK3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RIOK3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RIOK3 gene from 8/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Riok31 , 5 RIO kinase 3 (yeast)1, 5 90.12(n)1
    94.19(a)1
      18 (6.15 cM)5
    668781  NM_024182.41  NP_077144.21 
     121288505 
    chicken
    (Gallus gallus)
    Aves RIOK31 RIO kinase 3 (yeast) 80.18(n)
    87.52(a)
      421074  XM_419160.3  XP_419160.2 
    lizard
    (Anolis carolinensis)
    Reptilia RIOK36
    RIO kinase 3
    82(a)
    1 ↔ 1
    4(38289966-38308641)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685552 hypothetical protein MGC68555 80.04(n)    BC060398.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb10c112 Transcribed sequence with moderate similarity to protein more 78.06(n)    BI984728.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG30081 CG3008 51.14(n)
    48.35(a)
      33693  NM_135027.3  NP_608871.1 
    worm
    (Caenorhabditis elegans)
    Secernentea riok-31 Protein RIOK-3 48.88(n)
    39.44(a)
      176387  NM_066772.6  NP_499173.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RIO16
    Essential serine kinase involved in cell cycle pro...
    23(a)
    1 → many
    XV(548792-550246)


    ENSEMBL Gene Tree for RIOK3 (if available)
    TreeFam Gene Tree for RIOK3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RIOK3 gene
    RIOK12  
    1 SIMAP similar gene for RIOK3 using alignment to 6 protein entries:     RIOK3_HUMAN (see all proteins):
    RIOK1

    RIOK3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RIOK3
    PGOHUM00000248633


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/698 SNPs in RIOK3 are shown (see all 698)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1902140561,2
    --21030845(+) ACTGCA/CCTCCA 1 -- us2k10--------
    rs48004811,2
    C,A,H--21030851(+) ctccaG/Acctgg 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs454758921,2
    F--21031116(+) TACTCT/GAAGGA 1 -- us2k11Minor allele frequency- G:0.06NS 32
    rs734064581,2
    C--21031208(+) GCCAAT/CGCGGG 1 -- us2k13Minor allele frequency- C:0.32WA CSA EA 123
    rs1819028141,2
    --21031308(+) TGGCAA/CGCGCC 1 -- us2k10--------
    rs1142200751,2
    F--21031323(+) GTCCCA/GCCTAC 1 -- us2k11Minor allele frequency- G:0.04WA 118
    rs1864255551,2
    --21031331(+) TACTCA/GGAAGG 1 -- us2k10--------
    rs1481003981,2
    --21031400(+) GCCACC/TGCACT 1 -- us2k10--------
    rs454582061,2
    F--21031489(+) AAAAGT/GTAAAA 1 -- us2k11Minor allele frequency- G:0.27NS 26
    rs456215361,2
    F--21031491(+) AAGTTA/G/TAAAAA 1 -- us2k11NS 26

    HapMap Linkage Disequilibrium report for RIOK3 (21032787 - 21066567 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RIOK3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2716860CNV Deletion23290073
    esv2716859CNV Deletion23290073
    esv34149CNV Loss18971310
    nsv909458CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603579    OMIM disorders: --

    2 diseases for RIOK3:    About MalaCards
    alcoholism    melanoma


    RIOK3 for disorders           About GeneDecksing


    Export disorders for RIOK3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RIOK3 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with RIOK3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of the Aspergillus nidulans sudD gene and its human homologue. (PubMed id 9602165)1, 2, 3, 9 Anaya P.... May G.S. (1998)
    2. DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)1, 2 Nusbaum C.... Lander E.S. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. (PubMed id 19050074)1, 9 Kimmelman A.C....DePinho R.A. (2008)
    5. Human RioK3 is a novel component of cytoplasmic pre-40 S pre-ribosomal particles. (PubMed id 22418843)1 Baumas K....Mougin A. (2012)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8780 HGNC: 11451 AceView: RIOK3 Ensembl:ENSG00000101782 euGenes: HUgn8780
    ECgene: RIOK3 H-InvDB: RIOK3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RIOK3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RIOK3 gene:
    Search GeneIP for patents involving RIOK3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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