External Ids for RIN3 Gene
Previous GeneCards Identifiers for RIN3 Gene
RIN3 is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases (see RAB5A; MIM 179512) (Kajiho et al., 2003 [PubMed 12972505]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RIN3 Gene
RIN3 (Ras And Rab Interactor 3) is a Protein Coding gene. Diseases associated with RIN3 include paget's disease of bone. GO annotations related to this gene include GTPase activator activity and Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is RINL.
UniProtKB/Swiss-Prot for RIN3 Gene
Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.