RIN2 Gene
protein-coding GIFtS: 55
GCID: GC20P019818
|
|
Ras and Rab interactor 2
| |
Aliases
for RIN2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Ras And Rab Interactor 21 2 | | Ras Interaction/Interference Protein 22 3 | | RASSF41 2 3 | | MACS2 5 | | Ras Association Domain Family 42 3 | | RAB5 Interacting Protein 22 | | Ras Inhibitor JC2652 3 | | RAS Association (RalGDS/AF-6) Domain Containing Protein JC2652 |
| External Ids: | HGNC: 187501 | Entrez Gene: 544532 | Ensembl: ENSG000001326697 | OMIM: 6102225 | UniProtKB: Q8WYP33 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n339591 | |
Export aliases for RIN2 gene to outside databasesPrevious GC identifers: GC20P019858 GC20P019865
Summaries
for RIN2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RIN2:
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encodedby this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as aguanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm anddoes not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa andscoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2syndrome. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Jun 2011)
UniProtKB/Swiss-Prot: RIN2_HUMAN, Q8WYP3Function: Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocyticpathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins byexchanging bound GDP for free GTP
|
Genomic Views
for RIN2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RIN2 gene promoter:
STAT1 FOXF2 STAT5A Nkx2-5 RelA FOXC1 HSF2 FOXO4 Cart-1 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RIN2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RIN2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p11.22 Ensembl cytogenetic band: 20p11.23 HGNC cytogenetic band: 20p11.22RIN2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P019818: view genomic region
(about GC identifiers)
Start:
|
19,867,165 bp from pter |
End:
|
19,983,101 bp from pter |
Size:
|
115,937 bases |
Orientation:
|
plus strand |
|
Proteins
for RIN2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RIN2_HUMAN, Q8WYP3 (See
protein sequence)Recommended Name: Ras and Rab interactor 2 Size: 895 amino acids; 100163 Da
Subunit: Homotetramer; probably composed of anti-parallel linkage of two parallel dimers. Interacts with Ras. Interactswith RAB5B, with a much higher affinity for GTP-bound activated RAB5B. Does not interact with other members of the Rabfamily
Subcellular location: Cytoplasm (Probable)
Sequence caution: Sequence=CAB66858.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q00425 Q5TFT8 Q9BQL3 Q9H071Alternative splicing: 2 isoforms: Q8WYP3-1 Q8WYP3-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for RIN2: NX_Q8WYP3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WYP3
RIN2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001229510.1 NP_061866.1
ENSEMBL proteins: ENSP00000255006 ENSP00000391239
Human Recombinant Protein Products for RIN2:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RIN2 for ontologies About GeneDecksing
RIN2 Antibody Products:
Assay Products for RIN2: |
Protein
Domains /
Families
for RIN2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RIN2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WYP3ProtoNet protein and cluster: Q8WYP3 2 Blocks protein families: IPB000159 RA domain IPB003123 Vacuolar sorting protein 9
UniProtKB/Swiss-Prot: RIN2_HUMAN, Q8WYP3Similarity: Belongs to the RIN (Ras interaction/interference) familySimilarity: Contains 1 Ras-associating domainSimilarity: Contains 1 SH2 domainSimilarity: Contains 1 VPS9 domain |
Function
for RIN2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RIN2_HUMAN, Q8WYP3Function: Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocyticpathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins byexchanging bound GDP for free GTP Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
RIN2 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RIN2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RIN2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): RIN2 (NM_000833) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RIN2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RIN2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RIN2 |
|
Pathways & Interactions
for RIN2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Development HGF signaling pathway | |
1  BioSystems Pathway for RIN2
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RIN2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/12 Interacting proteins for RIN2 (Q8WYP32, 3 ENSP000002550064) via UniProtKB, MINT, STRING, and/or I2D (see all 12)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
RIN2 for ontologies About GeneDecksing
|
Drugs & Compounds
for RIN2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RIN2
3 HMDB Compounds for RIN2 About this table
Search CenterWatch for drugs/clinical trials and news about RIN2
|
Transcripts
for RIN2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RIN2 gene (2 alternative transcripts): NM_001242581.1 NM_018993.3 Unigene Cluster for RIN2: Ras and Rab interactor 2 Hs.472270 [show with all ESTs]Unigene Representative Sequence: NM_0012425817 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000255006(uc002wro.2 uc010gcu.2 uc010gcv.2) ENST00000459721
ENST00000467569 ENST00000488077 ENST00000465815 ENST00000484638 ENST00000440354
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RIN2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RIN2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): RIN2 (NM_000833) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RIN2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RIN2 |
Additional cDNA sequence: AB060339.1 AK094884.1 AL136924.1 BC034698.1 BC128065.1 M37190.1 4 DOTS entries: DT.453791 DT.91722574 DT.120836812 DT.40189001 24/114 AceView cDNA sequences (see all 114): AA424473 CA842793 CR617469 AL136924 BF195292 CK430955 AI695804 AI370835 CA398188 NM_018993 M37190 BM550342 BX494478 CB127356 BP337044 AI245470 AA932991 AA953394 AA573440 BI759195 R83224 AA341201 AA939080 AI688712
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for RIN2 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RIN2
|
Expression
for RIN2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RIN2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTGAAAATA
About this image
See RIN2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RIN2
SOURCE GeneReport for Unigene cluster: Hs.472270
UniProtKB/Swiss-Prot: RIN2_HUMAN, Q8WYP3Tissue specificity: Widely expressed. Expressed in heart, kidney, lung placenta. Expressed at low level in skeletalmuscle, spleen and peripheral blood
SABiosciences Custom PCR Arrays for RIN2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RIN2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RIN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RIN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RIN2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RIN2 |
Orthologs
for RIN2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RIN2 gene from 5/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RIN21 |
Ras and Rab interactor 2 |
76.52(n)
79.68(a) |
|
421246 XM_419317.3 XP_419317.1 |
lizard
(Anolis carolinensis) |
Reptilia |
RIN26 |
-- |
76(a) |
1 ↔ 1 |
4(80457274-80500280) |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1000066221 |
ras and Rab interactor 2-like |
61.88(n)
61.08(a) |
|
100006622 XM_001345278.2 XP_001345314.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
spri3 |
RAS interactor |
28(a) |
|
9D2 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
tag-3336 |
Temporarily Assigned Gene name family member (tag-... |
9(a) |
1 → many |
V(14784137-14815585) |
ENSEMBL Gene Tree for RIN2 (if available)
TreeFam Gene Tree for RIN2 (if available) |
Paralogs
for RIN2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RIN2 gene
- RINL2 RIN32 RIN12
3 SIMAP similar genes for RIN2 using alignment to 3 protein entries: RIN2_HUMAN (see all proteins):DKFZp762H1613 RIN3 RIN1
RIN2 for paralogs About GeneDecksing
|
Genomic Variants
for RIN2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RIN2 (19867165 - 19983101 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for RIN2
7 CNVs: 90496 6078 6079 79142 90497 9821 79140
3 Indels: 73477 79141 90495
Human Gene Mutation Database (HGMD): RIN2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RIN2 |
|
Disorders
/ Diseases
for RIN2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RIN2 for disorders About GeneDecksing
OMIM gene information: 610222
OMIM disorders: 613075
UniProtKB/Swiss-Prot: RIN2_HUMAN, Q8WYP3
Defects in RIN2 are the cause of MACS syndrome (MACS) [MIM:613075]; also called macrocephaly alopecia cutislaxa and scoliosis syndrome. MACS is an autosomal-recessive inherited complex disorder of elastic tissue,characterized by sagging skin and occasionally by life-threatening visceral complications
8  diseases for RIN2: About MalaCardsmacrocephaly, alopecia, cutis laxa, and scoliosis cutis laxa scoliosis alopecia
gingival hypertrophy bipolar disorder gingivitis schizophrenia
2 diseases from the University of Copenhagen DISEASES database for RIN2:Cutis laxa Gingival hypertrophy Export disorders for RIN2 gene to outside databases
|
Publications
for RIN2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RIN2 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with RIN2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5. (PubMed id 11733506)1, 2, 3 Saito K.... Katada T. (2002)
- Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae. (PubMed id 1849280)1, 2, 3 Colicelli J....Wigler M. (1991)
- RIN2 deficiency results in macrocephaly, alopecia, cu tis laxa, and scoliosis: MACS syndrome. (PubMed id 19631308)1, 2 Basel-Vanagaite L....Sprecher E. (2009)
- Involvement of the Ras-Ras-activated Rab5 guanine nucleotide exchange factor RIN2-Rab5 pathway in the hepatocyte growth factor-induced endocytosis of E-cadherin. (PubMed id 16423831)1, 3 Kimura T....Takai Y. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- A genome-wide meta-analysis identifies novel loci ass ociated with schizophrenia and bipolar disorder. (PubMed id 20889312)1 Wang K.S....Aragam N. (2010)
- The RIN2 syndrome: a new autosomal recessive connecti ve tissue disorder caused by deficiency of Ras and Rab interactor 2 (RIN2). (PubMed id 20424861)1 Syx D....Verloes A. (2010)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
|
External Searches for RIN2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RIN2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RIN2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RIN2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RIN2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RIN2 gene:
Search GeneIP for patents involving RIN2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RIN2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RIN2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RIN2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RIN2 | | | OriGene Protein Over-expression Lysate for RIN2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RIN2 | | OriGene 3'-UTR Clone for RIN2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RIN2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RIN2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RIN2 | | OriGene Custom Protein Services for RIN2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RIN2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RIN2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RIN2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RIN2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RIN2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RIN2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for RIN2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | RIN2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RIN2 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for RIN2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RIN2 |
| |  | |
|
|
|
GeneCards Homepage -
Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013
View Random Gene
|
Category
|
|
|
von Willebrand factor
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2013
, Weizmann Institute of Science. All Rights Reserved.
hostname: 356980-web2.xennexinc.com
index build: 106 solr: 1.4
|
