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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RIMS3 Gene

protein-coding GIFtS: 52
GCID: GC01M041086

regulating synaptic membrane exocytosis 3

Explore 2 diseases affiliated with
RIMS3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Regulating Synaptic Membrane Exocytosis 3¹ ²		Rab-3 Interacting Molecule 3²
NIM3¹ ² ⁵		Regulating Synaptic Membrane Exocytosis Protein 3²
RIM3¹ ²		KIAA0237³
Rab-3-Interacting Molecule 3² ³		Nim3³
RIM 3² ³		KIAA0137⁵
RIM3 Gamma² ³

External Ids:	HGNC: 21292¹	Entrez Gene: 9783²	Ensembl: ENSG00000117016⁷	OMIM: 611600⁵	UniProtKB: Q9UJD0³

Export aliases for RIMS3 gene to outside databases

Previous GC identifers: GC01M040549 GC01M040499 GC01M040505 GC01M040755 GC01M040858 GC01M039204

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RIMS3_HUMAN, Q9UJD0

Function: Regulates synaptic membrane exocytosis (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RIMS3 gene promoter:
E2F-4 E2F-3a E2F-5 NRSF form 1 E2F-2 NRSF form 2 GATA-1 YY1 E2F-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RIMS3 promoter sequence

Search SABiosciences Chromatin IP Primers for RIMS3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RIMS3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1pter-p22.2 Ensembl cytogenetic band: 1p34.2 HGNC cytogenetic band: 1pter-p22.2

RIMS3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RIMS3 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M041086: view genomic region (about GC identifiers)

Start:	41,086,351 bp from pter	End:	41,131,329 bp from pter
Size:	44,979 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RIMS3_HUMAN, Q9UJD0 (See protein sequence)

Recommended Name: Regulating synaptic membrane exocytosis protein 3

Size: 308 amino acids; 32796 Da

Subunit: Binds PPFIA3 (By similarity). Does not bind RAB3

Subcellular location: Cell junction, synapse (By similarity)

Sequence caution: Sequence=BAA13243.2; Type=Erroneous initiation;

Secondary accessions: D3DPV8 Q92511

Explore the universe of human proteins at neXtProt for RIMS3: NX_Q9UJD0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UJD0

RIMS3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055562.2

ENSEMBL proteins:

ENSP00000361769 ENSP00000361768

Human Recombinant Protein Products:

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	Novus Biologicals RIMS3 Protein Novus Biologicals RIMS3 Lysate
	Browse Sino Biological Recombinant Proteins
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	Uscn Proteins for RIMS3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030054	cell junction	IEA	--
GO:0045202	synapse	IEA	--

RIMS3 for ontologies About GeneDecksing

RIMS3 Antibody Products:

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	Uscn Antibodies for RIMS3
	ThermoFisher Antibodies for RIMS3

Assay Products for RIMS3:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for RIMS3
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	Uscn ELISAs and CLIAs for RIMS3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RIMS3 for domains About GeneDecksing

3 InterPro domains/families:

IPR008973 C2_Ca/lipid-bd_dom_CaLB

IPR018029 C2_membr_targeting

IPR000008 C2_Ca-dep

Graphical View of Domain Structure for InterPro Entry Q9UJD0

ProtoNet protein and cluster: Q9UJD0

1 Blocks protein family: IPB000008 C2 domain

UniProtKB/Swiss-Prot: RIMS3_HUMAN, Q9UJD0

Similarity: Contains 1 C2 domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RIMS3_HUMAN, Q9UJD0

Function: Regulates synaptic membrane exocytosis (By similarity)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RIMS3
		8/115 QIAGEN miScript miRNA Assays for microRNAs that regulate RIMS3 (see all 115):
		hsa-miR-579 hsa-miR-607 hsa-miR-642a hsa-miR-3194-5p hsa-miR-15a hsa-miR-1258 hsa-miR-128 hsa-miR-3921

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
Products:

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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RIMS3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RIMS3 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RIMS3
		Search LifeMap BioReagents cell lines for RIMS3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RIMS3

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0044325	ion channel binding	IEA	--

RIMS3 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for RIMS3:

Decreased TP53 protein express

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RIMS3

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

3 Interacting proteins for RIMS3 (Q9UJD0³ ENSP00000361768⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CREB3	O43889³	I2D: score=1
YWHAE	P62258³	I2D: score=1
GJA5	ENSP00000271348⁴	STRING: ENSP00000271348

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006836	neurotransmitter transport	IEA	--
GO:0006887	exocytosis	IEA	--
GO:0017156	calcium ion-dependent exocytosis	--	--
GO:0042391	regulation of membrane potential	IEA	--

RIMS3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RIMS3
Search CenterWatch for drugs/clinical trials and news about RIMS3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RIMS3 gene:

NM_014747.2

Unigene Cluster for RIMS3:

Regulating synaptic membrane exocytosis 3

Hs.654808 [show with all ESTs]

Unigene Representative Sequence: D87074

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000372684(uc001cfu.1 uc001cfv.1) ENST00000372683

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RIMS3
		8/115 QIAGEN miScript miRNA Assays for microRNAs that regulate RIMS3 (see all 115):
		hsa-miR-579 hsa-miR-607 hsa-miR-642a hsa-miR-3194-5p hsa-miR-15a hsa-miR-1258 hsa-miR-128 hsa-miR-3921

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RIMS3 (see all 7) OriGene shRNA RFP: RIMS3 OriGene siRNA: RIMS3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RIMS3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RIMS3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RIMS3 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RIMS3 (NM_014747)
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RIMS3 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RIMS3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RIMS3

Additional cDNA sequence:

AY326956.1 BC003103.1 D87074.1

2 DOTS entries:

DT.413753 DT.91748411

24/102 AceView cDNA sequences (see all 102):

AA626438 BM478119 BE397286 AA456423 BE312243 BQ721347 AW291735 BQ064934

BC003103 BU930896 NM_014747 AU120066 AI346380 BI820965 AY326956 BU681931

BM053119 D87074 AI274884 BE261795 CR619233 BU848876 BP362770 BU156647

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for RIMS3 About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10
SP1:
SP2:					-
SP3:

ECgene alternative splicing isoforms for RIMS3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RIMS3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTAAAGTCA

About this image

RIMS3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 4 LifeMap Cells

Name

Category

PureStem™ progenitor E68 (Embryonic Progenitor Cell)

PureStem™ progenitor T42 (Embryonic Progenitor Cell)

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RIMS3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RIMS3

SOURCE GeneReport for Unigene cluster: Hs.654808

SABiosciences Custom PCR Arrays for RIMS3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RIMS3 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RIMS3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RIMS3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RIMS3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for RIMS3 gene from 5/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	RIMS3¹	regulating synaptic membrane exocytosis 3	79.61(n) 81.91(a)		428226 XM_425785.2 XP_425785.2
lizard (Anolis carolinensis)	Reptilia	RIMS3⁶	--	80(a)	1 ↔ 1	GL343308.1(133429-151923)
zebrafish (Danio rerio)	Actinopterygii	rims3¹	regulating synaptic membrane exocytosis 3	74.02(n) 79.93(a)		563414 NM_001100009.2 NP_001093479.1
fruit fly (Drosophila melanogaster)	Insecta	Rim⁶	Rim	4(a)	1 → many	3R(13698470-13742300)
worm (Caenorhabditis elegans)	Secernentea	unc-10⁶	Rab-3-interacting molecule unc-10	7(a)	1 → many	X(7272279-7280275)

ENSEMBL Gene Tree for RIMS3 (if available)
TreeFam Gene Tree for RIMS3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RIMS3 gene

RIMS1² RIMS2² RIMS4²

3 SIMAP similar genes for RIMS3 using alignment to 2 protein entries: RIMS3_HUMAN (see all proteins):

RIMS2 RIMS4 RIMS1

RIMS3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs12059305^1,2	C,F,H,	--	41085926(+)	`ATCAGG/ATGTGG`	1	--	ds500¹		17		NS EA NA CSA WA	2222
rs182151707^1,2		--	41085937(+)	`CTGCAA/GTAAGC`	1	--	ds500¹		0	--	--	--	--
rs111614024^1,2	C,	--	41085967(+)	`GAGCTA/GCTGGA`	1	--	ds500¹		0	--	--	--	--
rs186831312^1,2		--	41086014(+)	`AGCTGC/TGGCCT`	1	--	ds500¹		0	--	--	--	--
rs137951123^1,2		--	41086045(+)	`CTGTCA/GTTGGA`	1	--	ds500¹		0	--	--	--	--
rs149205789^1,2		--	41086077(+)	`AAGTAG/TAAGGC`	1	--	ds500¹		0	--	--	--	--
rs137970063^1,2		--	41086116(+)	`GAGAC-/AGAGCC`	1	--	ds500¹		0	--	--	--	--
rs12125724^1,2	C,F,A,H,	--	41086224(+)	`ATGCTC/TTTTTT`	1	--	ds500¹		33		NS EA NA WA CSA	3376
rs116096348^1,2	C,F,	--	41086396(+)	`ATACTG/TTACAT`	1	--	ut3¹		1		WA	118
rs117472915^1,2		--	41086527(+)	`TGCTGC/TACATA`	1	--	ut3¹		1		EA	120

HapMap Linkage Disequilibrium report for RIMS3 (41086351 - 41131329 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RIMS3: --
Human Gene Mutation Database (HGMD): RIMS3

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RIMS3

DNA2.0 Custom Variant and Variant Library Synthesis for RIMS3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RIMS3 for disorders           About GeneDecksing

OMIM gene information: 611600    OMIM disorders: --

2 diseases for RIMS3:    About MalaCards

schizophrenia neuronitis

Human Genome Epidemiology (HuGE) Navigator: RIMS3 (1 document)

Export disorders for RIMS3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RIMS3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RIMS3)

Utopia: connect your pdf to the dynamic
world of online information

Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins. (PubMed id 12620390)^{1, 2, 3} Wang Y. and Suedhof T.C. (2003)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins. (PubMed id 10748113)^{1, 3} Wang Y....Sudhof T.C. (2000)
Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)^{1, 2} Nagase T....Nomura N. (1996)
A de novo 1p34.2 microdeletion identifies the synapti c vesicle gene RIMS3 as a novel candidate for autism. (PubMed id 19546099)¹ Kumar R.A....Dobyns W.B. (2010)
Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs. (PubMed id 18490030)¹ Weidenhofer J....Tooney P.A. (2009)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)² Matsuoka S.... Elledge S.J. (2007)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)¹ Olsen J.V....Mann M. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 9783	HGNC: 21292	AceView: RIMS3	Ensembl:ENSG00000117016	euGenes: HUgn9783
ECgene: RIMS3	H-InvDB: RIMS3

(According to HUGE)
About This Section

HUGE: KIAA0137 KIAA0237

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RIMS3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RIMS3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RIMS3 gene:
Search GeneIP for patents involving RIMS3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	OriGene Antibodies for RIMS3		OriGene shRNA RFP for RIMS3
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RIMS3		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RIMS3
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	Regulatory tfbs in RIMS3 promoter
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	Browse SwitchGear 3'UTR luciferase reporter plasmids for RIMS3
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ThermoFisher Antibodies for RIMS3

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RIMS3

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes RIMS3 gene at Home site.

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RIMS3 Gene

regulating synaptic membrane exocytosis 3

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RIMS3 Gene

regulating synaptic membrane exocytosis 3

Aliasesfor RIMS3 gene

Summariesfor RIMS3 gene

Genomic Viewsfor RIMS3 gene

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Aliases
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for RIMS3 gene

Genomic Views
for RIMS3 gene

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for RIMS3 gene

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for RIMS3 gene

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for RIMS3 gene

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for RIMS3 gene

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for RIMS3 gene

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for RIMS3 gene

Expression
for RIMS3 gene

Orthologs
for RIMS3 gene

Paralogs
for RIMS3 gene

Genomic Variants
for RIMS3 gene

Disorders / Diseases
for RIMS3 gene

Publications
for RIMS3 gene

Intellectual Property
for RIMS3 gene

Products
for RIMS3 gene