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Aliases for RIMBP3C Gene

Aliases for RIMBP3C Gene

  • RIMS Binding Protein 3C 2 3
  • RIMS-Binding Protein 3.3 3 4
  • RIM-BP3.3 3 4
  • RIM-BP3.C 3 4
  • RIMS Binding Protein 3.3 3
  • RIMBP3.3 3

External Ids for RIMBP3C Gene

Previous GeneCards Identifiers for RIMBP3C Gene

  • GC22M020232
  • GC22M021900

Summaries for RIMBP3C Gene

GeneCards Summary for RIMBP3C Gene

RIMBP3C (RIMS Binding Protein 3C) is a Protein Coding gene. An important paralog of this gene is RIMBP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RIMBP3C Gene

Genomics for RIMBP3C Gene

Regulatory Elements for RIMBP3C Gene

Genomic Location for RIMBP3C Gene

21,545,357 bp from pter
21,551,461 bp from pter
6,105 bases
Minus strand

Genomic View for RIMBP3C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RIMBP3C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RIMBP3C Gene

Proteins for RIMBP3C Gene

  • Protein details for RIMBP3C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RIMS-binding protein 3C
    Protein Accession:

    Protein attributes for RIMBP3C Gene

    1639 amino acids
    Molecular mass:
    180950 Da
    Quaternary structure:
    • Interacts with FASLG.

neXtProt entry for RIMBP3C Gene

Proteomics data for RIMBP3C Gene at MOPED

Post-translational modifications for RIMBP3C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RIMBP3C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RIMBP3C Gene

Domains & Families for RIMBP3C Gene

Protein Domains for RIMBP3C Gene

Suggested Antigen Peptide Sequences for RIMBP3C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 fibronectin type-III domains.
  • Belongs to the RIMBP family.
  • Contains 2 fibronectin type-III domains.
  • Contains 3 SH3 domains.
  • Belongs to the RIMBP family.
genes like me logo Genes that share domains with RIMBP3C: view

No data available for Gene Families for RIMBP3C Gene

Function for RIMBP3C Gene

Gene Ontology (GO) - Molecular Function for RIMBP3C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with RIMBP3C: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RIMBP3C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for RIMBP3C Gene

Localization for RIMBP3C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RIMBP3C Gene

Pathways & Interactions for RIMBP3C Gene

SuperPathways for RIMBP3C Gene

No Data Available

Interacting Proteins for RIMBP3C Gene

Selected Interacting proteins: A6NJZ7-RIM3C_HUMAN for RIMBP3C Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for RIMBP3C Gene


No data available for Pathways by source and SIGNOR curated interactions for RIMBP3C Gene

Drugs & Compounds for RIMBP3C Gene

No Compound Related Data Available

Transcripts for RIMBP3C Gene

mRNA/cDNA for RIMBP3C Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(29) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RIMBP3C Gene

RIMS binding protein 3C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RIMBP3C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RIMBP3C Gene

No ASD Table

Relevant External Links for RIMBP3C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RIMBP3C Gene

mRNA expression in normal human tissues for RIMBP3C Gene

mRNA expression in normal human tissues for RIMBP3C Gene

SOURCE GeneReport for Unigene cluster for RIMBP3C Gene Hs.447643

genes like me logo Genes that share expression patterns with RIMBP3C: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RIMBP3C Gene

Orthologs for RIMBP3C Gene

This gene was present in the common ancestor of animals.

Orthologs for RIMBP3C Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RIMBP3B 35
  • 75.37 (n)
  • 62.68 (a)
-- 36
  • 58 (a)
(Canis familiaris)
Mammalia LOC486445 35
  • 79.31 (n)
  • 69.18 (a)
(Mus musculus)
Mammalia Rimbp3 35
  • 73.66 (n)
  • 64.86 (a)
Rimbp3 36
  • 59 (a)
(Rattus norvegicus)
Mammalia Rimbp3 35
  • 73.95 (n)
  • 65.41 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 37 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
(Gallus gallus)
Aves -- 36
  • 26 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 37 (a)
(Danio rerio)
Actinopterygii si:ch211-105f12.2 36
  • 30 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rbp 36
  • 13 (a)
(Caenorhabditis elegans)
Secernentea tag-168 36
  • 16 (a)
Species with no ortholog for RIMBP3C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RIMBP3C Gene

Gene Tree for RIMBP3C (if available)
Gene Tree for RIMBP3C (if available)

Paralogs for RIMBP3C Gene

Paralogs for RIMBP3C Gene

(2) SIMAP similar genes for RIMBP3C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with RIMBP3C: view

Variants for RIMBP3C Gene

Sequence variations from dbSNP and Humsavar for RIMBP3C Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs7926 -- 21,545,903(-) TTAAG(C/T)GTCCC utr-variant-3-prime
rs364215 -- 21,546,879(+) CTGGC(A/G)CCCAG reference, synonymous-codon
rs484252 -- 21,546,328(-) GCTCA(C/T)CATCC missense, reference
rs618488 -- 21,545,512(-) ctgtg(C/T)gctca downstream-variant-500B
rs1610467 -- 21,546,735(+) GGGGT(C/G)AAGAG synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for RIMBP3C Gene

Variant ID Type Subtype PubMed ID
nsv436864 CNV Insertion 17901297
nsv437849 CNV Loss 16327808
esv28075 CNV Gain+Loss 19812545
nsv471490 CNV Duplication 19718026
dgv4874n71 CNV Gain 21882294
nsv914437 CNV Gain 21882294
dgv4875n71 CNV Gain 21882294
nsv914443 CNV Loss 21882294
nsv914444 CNV Gain 21882294
dgv4877n71 CNV Gain 21882294
nsv7350 OTHER Inversion 18451855
nsv428386 CNV Loss 18775914
nsv914448 CNV Loss 21882294
dgv4878n71 CNV Gain 21882294
nsv469545 CNV Gain 16826518
nsv471596 CNV Gain+Loss 15918152
dgv819e199 CNV Deletion 23128226
esv2661723 CNV Deletion 23128226
nsv511071 OTHER Inversion 20534489
nsv442791 CNV CNV 18776908
nsv914458 CNV Loss 21882294
nsv834145 CNV Loss 17160897
nsv914461 CNV Gain 21882294
esv2678291 CNV Deletion 23128226
esv25508 CNV Gain+Loss 19812545
dgv820e199 CNV Deletion 23128226

Variation tolerance for RIMBP3C Gene

Gene Damage Index Score: 0.00; 0.02% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RIMBP3C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RIMBP3C Gene

Disorders for RIMBP3C Gene

Relevant External Links for RIMBP3C

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with RIMBP3C: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RIMBP3C Gene

Publications for RIMBP3C Gene

  1. Structure and evolution of RIM-BP genes: identification of a novel family member. (PMID: 17855024) Mittelstaedt T. … Schoch S. (Gene 2007) 2 67
  2. Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PMID: 19807924) Voss M. … Janssen O. (BMC Immunol. 2009) 67
  3. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. (PMID: 19838193) Han J.W. … Zhang X.J. (Nat. Genet. 2009) 67
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 67
  5. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 67

Products for RIMBP3C Gene

Sources for RIMBP3C Gene

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