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Aliases for RIMBP3B Gene

Aliases for RIMBP3B Gene

  • RIMS Binding Protein 3B 2 3 5
  • RIMS-Binding Protein 3.2 3 4
  • RIM-BP3.2 3 4
  • RIM-BP3.B 3 4
  • RIMS Binding Protein 3.2 3
  • RIMS-Binding Protein 3B 3
  • RIMBP3.2 3

External Ids for RIMBP3B Gene

Previous GeneCards Identifiers for RIMBP3B Gene

  • GC22P020067
  • GC22P021738
  • GC22P021759
  • GC22P021775
  • GC22P021797
  • GC22P021451
  • GC22P021489
  • GC22P021512

Summaries for RIMBP3B Gene

GeneCards Summary for RIMBP3B Gene

RIMBP3B (RIMS Binding Protein 3B) is a Protein Coding gene. An important paralog of this gene is RIMBP3C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RIMBP3B Gene

Genomics for RIMBP3B Gene

Regulatory Elements for RIMBP3B Gene

Promoters for RIMBP3B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for RIMBP3B Gene

21,383,374 bp from pter
21,389,478 bp from pter
6,105 bases
Plus strand

Genomic View for RIMBP3B Gene

Genes around RIMBP3B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RIMBP3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RIMBP3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RIMBP3B Gene

Proteins for RIMBP3B Gene

  • Protein details for RIMBP3B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RIMS-binding protein 3B
    Protein Accession:

    Protein attributes for RIMBP3B Gene

    1639 amino acids
    Molecular mass:
    180952 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RIMBP3B Gene

Post-translational modifications for RIMBP3B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RIMBP3B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RIMBP3B Gene

Domains & Families for RIMBP3B Gene

Protein Domains for RIMBP3B Gene

Suggested Antigen Peptide Sequences for RIMBP3B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 fibronectin type-III domains.
  • Belongs to the RIMBP family.
  • Contains 2 fibronectin type-III domains.
  • Contains 3 SH3 domains.
  • Belongs to the RIMBP family.
genes like me logo Genes that share domains with RIMBP3B: view

No data available for Gene Families for RIMBP3B Gene

Function for RIMBP3B Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RIMBP3B Gene

Localization for RIMBP3B Gene

Subcellular locations from

Jensen Localization Image for RIMBP3B Gene COMPARTMENTS Subcellular localization image for RIMBP3B gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RIMBP3B Gene

Pathways & Interactions for RIMBP3B Gene

SuperPathways for RIMBP3B Gene

No Data Available

Interacting Proteins for RIMBP3B Gene

Selected Interacting proteins: A6NNM3-RIM3B_HUMAN for RIMBP3B Gene via IID

Gene Ontology (GO) - Biological Process for RIMBP3B Gene


No data available for Pathways by source and SIGNOR curated interactions for RIMBP3B Gene

Drugs & Compounds for RIMBP3B Gene

No Compound Related Data Available

Transcripts for RIMBP3B Gene

mRNA/cDNA for RIMBP3B Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(37) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RIMBP3B Gene

RIMS binding protein 3B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RIMBP3B Gene

No ASD Table

Relevant External Links for RIMBP3B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RIMBP3B Gene

mRNA expression in normal human tissues for RIMBP3B Gene

mRNA differential expression in normal tissues according to GTEx for RIMBP3B Gene

This gene is overexpressed in Testis (x42.8).

NURSA nuclear receptor signaling pathways regulating expression of RIMBP3B Gene:


SOURCE GeneReport for Unigene cluster for RIMBP3B Gene:

genes like me logo Genes that share expression patterns with RIMBP3B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RIMBP3B Gene

Orthologs for RIMBP3B Gene

This gene was present in the common ancestor of mammals.

Orthologs for RIMBP3B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RIMBP3B 34
  • 75.6 (n)
  • 62.82 (a)
(Canis familiaris)
Mammalia LOC486445 34
  • 79.31 (n)
  • 69.18 (a)
(Mus musculus)
Mammalia Rimbp3 34
  • 73.66 (n)
  • 64.86 (a)
(Rattus norvegicus)
Mammalia Rimbp3 34
  • 73.97 (n)
  • 65.41 (a)
Species where no ortholog for RIMBP3B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RIMBP3B Gene

Gene Tree for RIMBP3B (if available)
Gene Tree for RIMBP3B (if available)

Paralogs for RIMBP3B Gene

Paralogs for RIMBP3B Gene

(2) SIMAP similar genes for RIMBP3B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RIMBP3B: view

Variants for RIMBP3B Gene

Sequence variations from dbSNP and Humsavar for RIMBP3B Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs861802 -- 21,388,029(+) ATCTG(C/T)GGGGC reference, missense
rs861803 -- 21,389,425(+) gagct(C/T)tcAGA downstream-variant-500B
rs9606856 -- 21,388,137(+) CGGCA(C/T)TGTGT reference, synonymous-codon
rs9609294 -- 21,382,386(+) tcgca(A/G)cactt upstream-variant-2KB
rs9609298 -- 21,383,576(+) TGCTA(A/G)TAGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RIMBP3B Gene

Variant ID Type Subtype PubMed ID
dgv4486n100 CNV gain 25217958
dgv4487n100 CNV gain 25217958
dgv4488n100 CNV gain 25217958
dgv4489n100 CNV gain 25217958
dgv4491n100 CNV gain 25217958
dgv7996n54 CNV gain 21841781
dgv819e199 CNV deletion 23128226
dgv820e199 CNV deletion 23128226
esv25508 CNV gain+loss 19812545
esv2661723 CNV deletion 23128226
esv2678291 CNV deletion 23128226
esv2760719 CNV gain 21179565
esv2763699 CNV gain+loss 21179565
esv28075 CNV gain+loss 19812545
esv3584494 CNV gain 24956385
esv3893444 CNV gain 25118596
nsv1066391 CNV gain 25217958
nsv1072204 CNV deletion 25765185
nsv1072625 CNV deletion 25765185
nsv1118945 CNV deletion 24896259
nsv1160729 CNV duplication 26073780
nsv1160730 CNV deletion 26073780
nsv428386 CNV loss 18775914
nsv436864 CNV insertion 17901297
nsv437849 CNV loss 16327808
nsv442791 CNV gain 18776908
nsv469545 CNV gain 16826518
nsv471490 CNV gain 19718026
nsv471596 CNV gain+loss 15918152
nsv511071 OTHER inversion 20534489
nsv7350 OTHER inversion 18451855
nsv834145 CNV loss 17160897
nsv953041 CNV deletion 24416366
nsv953042 CNV deletion 24416366
nsv962765 CNV duplication 23825009
nsv966082 CNV duplication 23825009

Variation tolerance for RIMBP3B Gene

Gene Damage Index Score: 1.18; 23.80% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RIMBP3B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RIMBP3B Gene

Disorders for RIMBP3B Gene

Relevant External Links for RIMBP3B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RIMBP3B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RIMBP3B Gene

Publications for RIMBP3B Gene

  1. Structure and evolution of RIM-BP genes: identification of a novel family member. (PMID: 17855024) Mittelstaedt T. … Schoch S. (Gene 2007) 2 3 65
  2. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 65
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 4 65

Products for RIMBP3B Gene

Sources for RIMBP3B Gene

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