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Aliases for RIMBP3 Gene

Aliases for RIMBP3 Gene

  • RIMS Binding Protein 3 2 3
  • RIMBP3A 3 4 6
  • RIM-BP3.1 3 4
  • RIM-BP3.A 3 4
  • KIAA1666 4 6
  • RIMS Binding Protein 3.1 3
  • RIMS-Binding Protein 3.1 4
  • RIMS-Binding Protein 3A 3
  • RIMBP3.1 3
  • RIM-BP3 3

External Ids for RIMBP3 Gene

Previous GeneCards Identifiers for RIMBP3 Gene

  • GC22M018843
  • GC22M020456
  • GC22M003946

Summaries for RIMBP3 Gene

GeneCards Summary for RIMBP3 Gene

RIMBP3 (RIMS Binding Protein 3) is a Protein Coding gene. An important paralog of this gene is RIMBP3B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RIMBP3 Gene

Genomics for RIMBP3 Gene

Regulatory Elements for RIMBP3 Gene

Genomic Location for RIMBP3 Gene

18,605,815 bp from pter
18,611,919 bp from pter
6,105 bases
Minus strand

Genomic View for RIMBP3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RIMBP3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RIMBP3 Gene

Proteins for RIMBP3 Gene

  • Protein details for RIMBP3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RIMS-binding protein 3A
    Protein Accession:
    Secondary Accessions:
    • Q8IYP7
    • Q9BY94
    • Q9UFQ5

    Protein attributes for RIMBP3 Gene

    1639 amino acids
    Molecular mass:
    180717 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH35246.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB33336.1; Type=Frameshift; Positions=652; Evidence={ECO:0000305}; Sequence=CAB61362.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for RIMBP3 Gene

neXtProt entry for RIMBP3 Gene

Proteomics data for RIMBP3 Gene at MOPED

Post-translational modifications for RIMBP3 Gene

  • Ubiquitination at Lys1226
  • Modification sites at PhosphoSitePlus

Other Protein References for RIMBP3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RIMBP3 Gene

Domains for RIMBP3 Gene

Protein Domains for RIMBP3 Gene


Suggested Antigen Peptide Sequences for RIMBP3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9UFD9
  • Contains 2 fibronectin type-III domains.
  • Contains 3 SH3 domains.
  • Belongs to the RIMBP family.
genes like me logo Genes that share domains with RIMBP3: view

No data available for Gene Families for RIMBP3 Gene

Function for RIMBP3 Gene

Gene Ontology (GO) - Molecular Function for RIMBP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with RIMBP3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RIMBP3 Gene

Localization for RIMBP3 Gene

Subcellular locations from

Jensen Localization Image for RIMBP3 Gene COMPARTMENTS Subcellular localization image for RIMBP3 gene
Compartment Confidence
nucleus 3
cytosol 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RIMBP3 Gene

Pathways for RIMBP3 Gene

SuperPathways for RIMBP3 Gene

No Data Available

Interacting Proteins for RIMBP3 Gene

Gene Ontology (GO) - Biological Process for RIMBP3 Gene


No data available for Pathways by source for RIMBP3 Gene

Transcripts for RIMBP3 Gene

mRNA/cDNA for RIMBP3 Gene

(29) Selected AceView cDNA sequences:
(4) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RIMBP3 Gene

RIMS binding protein 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RIMBP3 Gene

No ASD Table

Relevant External Links for RIMBP3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RIMBP3 Gene

mRNA expression in normal human tissues for RIMBP3 Gene

mRNA differential expression in normal tissues according to GTEx for RIMBP3 Gene

This gene is overexpressed in Testis (41.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for RIMBP3 Gene

SOURCE GeneReport for Unigene cluster for RIMBP3 Gene Hs.115429

genes like me logo Genes that share expressions with RIMBP3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for RIMBP3 Gene

Orthologs for RIMBP3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RIMBP3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RIMBP3B 35
  • 75.55 (n)
  • 62.76 (a)
(Canis familiaris)
Mammalia LOC486445 35
  • 79.39 (n)
  • 69.43 (a)
(Mus musculus)
Mammalia Rimbp3 35
  • 73.68 (n)
  • 64.92 (a)
(Rattus norvegicus)
Mammalia Rimbp3 35
  • 73.95 (n)
  • 65.41 (a)
Species with no ortholog for RIMBP3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RIMBP3 Gene

Gene Tree for RIMBP3 (if available)
Gene Tree for RIMBP3 (if available)

Paralogs for RIMBP3 Gene

Paralogs for RIMBP3 Gene

Selected SIMAP similar genes for RIMBP3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RIMBP3: view

Variants for RIMBP3 Gene

Sequence variations from dbSNP and Humsavar for RIMBP3 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs444978 -- 18,612,353(-) tgtgt(A/G)tgtgt upstream-variant-2KB
rs467231 -- 18,612,310(-) GCTCA(A/G)GATGC upstream-variant-2KB
rs468289 -- 18,608,789(+) CTTGA(C/G)GATGG missense, reference
rs468996 -- 18,607,494(-) TTGCT(A/C)CCAGC missense, reference
rs469343 -- 18,605,846(-) CTGTC(C/T)TATGT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for RIMBP3 Gene

Variant ID Type Subtype PubMed ID
nsv435744 CNV Deletion 17901297
dgv16n31 CNV Duplication 19718026
nsv518950 CNV Gain 19592680
esv33990 CNV Loss 17666407
nsv820540 CNV Duplication 20802225
esv26930 CNV Gain+Loss 19812545
dgv4865n71 CNV Gain 21882294
nsv914377 CNV Gain 21882294
nsv510803 CNV Loss 20534489
nsv914378 CNV Gain 21882294
dgv4866n71 CNV Gain 21882294
nsv436867 CNV Insertion 17901297
nsv914381 CNV Gain+Loss 21882294
dgv817e199 CNV Deletion 23128226

Relevant External Links for RIMBP3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RIMBP3 Gene

Disorders for RIMBP3 Gene

No disorders were found for RIMBP3 Gene.

No data available for UniProtKB/Swiss-Prot for RIMBP3 Gene

Publications for RIMBP3 Gene

  1. Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping. (PMID: 11258795) Hirosawa M. … Ohara O. (DNA Res. 2001) 2 3 4
  2. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Structure and evolution of RIM-BP genes: identification of a novel family member. (PMID: 17855024) Mittelstaedt T. … Schoch S. (Gene 2007) 2 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for RIMBP3 Gene

Sources for RIMBP3 Gene

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