Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RILPL1 Gene

protein-coding GIFtS: 46
GCID: GC12M123955

Rab interacting lysosomal protein-like 1

Explore 1 disease affiliated with
RILPL1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Rab Interacting Lysosomal Protein-Like 1¹ ²
Rab-Interacting Lysosomal-Like Protein 1² ³
RLP1² ³
FLJ39378¹
GOSPEL²
RILP-Like Protein 1²

External Ids:	HGNC: 26814¹	Entrez Gene: 353116²	Ensembl: ENSG00000188026⁷	OMIM: 614092⁵	UniProtKB: Q5EBL4³

Export aliases for RILPL1 gene to outside databases

Previous GC identifers: GC12M122522 GC12M120917

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RIPL1_HUMAN, Q5EBL4

Function: Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of

GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology

and distribution

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_009755.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RILPL1 gene promoter:
Max1 AML1a HTF GCNF AP-4 Evi-1 GCNF-1 GCNF-2 c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RILPL1 promoter sequence

Search SABiosciences Chromatin IP Primers for RILPL1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RILPL1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31 Ensembl cytogenetic band: 12q24.31 HGNC cytogenetic band: 12q24.31

RILPL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RILPL1 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M123955: view genomic region (about GC identifiers)

Start:	123,955,909 bp from pter	End:	124,018,265 bp from pter
Size:	62,357 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RIPL1_HUMAN, Q5EBL4 (See protein sequence)

Recommended Name: RILP-like protein 1

Size: 403 amino acids; 47108 Da

Subunit: Interacts (when S-nitrosylated) with GAPDH (By similarity)

Subcellular location: Cytoplasm, cytosol

Secondary accessions: Q66K36 Q8N1M0

Alternative splicing: 3 isoforms: Q5EBL4-1 Q5EBL4-2 Q5EBL4-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RILPL1: NX_Q5EBL4

Post-translational modifications:

S-nitrosylation is required for the interaction with GAPDH (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q5EBL4

RILPL1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_847884.2

ENSEMBL proteins:

ENSP00000366070 ENSP00000345874 ENSP00000442991

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: RILPL1 OriGene Protein Over-expression Lysate: RILPL1 OriGene Custom Protein Services for RILPL1
	GenScript Custom Purified and Recombinant Proteins Services for RILPL1
	Novus Biologicals RILPL1 Protein Novus Biologicals RILPL1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for RILPL1

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IDA	--
GO:0005829	cytosol	ISS	--
GO:0005886	plasma membrane	IDA	--

RILPL1 for ontologies About GeneDecksing

RILPL1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for RILPL1
	GenScript Custom Superior Antibodies Services for RILPL1
	Novus Biologicals RILPL1 Antibodies
	Search for Antibodies for RILPL1 at Abcam
	Uscn Antibodies for RILPL1
	ThermoFisher Antibodies for RILPL1

Assay Products for RILPL1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RILPL1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RILPL1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RILPL1 for domains About GeneDecksing

2 InterPro domains/families:

IPR019143 JNK/Rab-associated_protein-1_N

IPR021563 RILP

Graphical View of Domain Structure for InterPro Entry Q5EBL4

ProtoNet protein and cluster: Q5EBL4

UniProtKB/Swiss-Prot: RIPL1_HUMAN, Q5EBL4

Similarity: Belongs to the RILPL family

Similarity: Contains 1 RILP-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RIPL1_HUMAN, Q5EBL4

Function: Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of

GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology

and distribution

miRNA Products:		OriGene 3'-UTR Clone: RILPL1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RILPL1
		8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate RILPL1 (see all 15):
		hsa-miR-217 hsa-miR-100* hsa-miR-3152-3p hsa-miR-4328 hsa-miR-509-5p hsa-miR-1278 hsa-miR-3171 hsa-miR-3922-3p

		SwitchGear 3'UTR luciferase reporter plasmid: RILPL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RILPL1 Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RILPL1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for RILPL1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RILPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RILPL1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RILPL1 (NM_178314)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RILPL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RILPL1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RILPL1
		Search LifeMap BioReagents cell lines for RILPL1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RILPL1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--

RILPL1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RILPL1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for RILPL1 (Q5EBL4³ ENSP00000366070⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
APC	P25054³	I2D: score=1
PHKB	ENSP00000313504⁴	STRING: ENSP00000313504

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0043526	neuroprotection	--	--
GO:1901214	regulation of neuron death	ISS	--

RILPL1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RILPL1
Search CenterWatch for drugs/clinical trials and news about RILPL1 / RIPL1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RILPL1 gene:

NM_178314.3

Unigene Cluster for RILPL1:

Rab interacting lysosomal protein-like 1

Hs.530315 [show with all ESTs]

Unigene Representative Sequence: BC041375

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000376874(uc001ufd.2 uc001ufe.2 uc010tas.1) ENST00000340724

ENST00000544468

miRNA Products:		OriGene 3'-UTR Clone: RILPL1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RILPL1
		8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate RILPL1 (see all 15):
		hsa-miR-217 hsa-miR-100* hsa-miR-3152-3p hsa-miR-4328 hsa-miR-509-5p hsa-miR-1278 hsa-miR-3171 hsa-miR-3922-3p

		SwitchGear 3'UTR luciferase reporter plasmid: RILPL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RILPL1 Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RILPL1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RILPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RILPL1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RILPL1 (NM_178314)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RILPL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RILPL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RILPL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RILPL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RILPL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RILPL1

Additional cDNA sequence:

AK096697.1 AK097550.1 BC041375.1 BC080626.1 BC089444.1

12 DOTS entries:

DT.92421480 DT.100776417 DT.97796895 DT.87046251 DT.214214 DT.102828354 DT.121175260 DT.405892

DT.91896440 DT.100744930 DT.100776415 DT.97793965

24/105 AceView cDNA sequences (see all 105):

AI734180 BM508077 CA441706 BF437352 AI453241 NM_180703 AA211268 BU682752

AA487864 BC054034 CA307572 BM797196 BM714052 BM717649 BC020829 BU856880

AA301542 NM_180699 BC028485 BM998075 BM694072 BM704623 AW975762 AA487865

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for RILPL1 (see all 6) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11	^	12a	·	12b
SP1:							-		-		-										-
SP2:							-		-		-										-				-
SP3:									-		-										-
SP4:											-
SP5:

ECgene alternative splicing isoforms for RILPL1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RILPL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAGCAATGTT

About this image

RILPL1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Lens

Eye

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RILPL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RILPL1

SOURCE GeneReport for Unigene cluster: Hs.530315

UniProtKB/Swiss-Prot: RIPL1_HUMAN, Q5EBL4

Tissue specificity: Widely expressed. Expressed at lower level in liver and kidney

SABiosciences Custom PCR Arrays for RILPL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RILPL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RILPL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RILPL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RILPL1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RILPL1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for RILPL1 gene from 7/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Rilpl1^{1 , 5}	Rab interacting lysosomal protein-like 1^{1, 5}	87.84(n)¹ 93.55(a)¹		5 (63.62 cM)⁵ 75695¹ NM_021430.2¹ NP_067405.1¹ 124493082⁵
chicken (Gallus gallus)	Aves	RILPL1¹	Rab interacting lysosomal protein-like 1	77.55(n) 85.86(a)		416822 XM_415113.3 XP_415113.2
lizard (Anolis carolinensis)	Reptilia	RILPL1⁶	--	79(a)	1 ↔ 1	LGb(1782913-1795965)
African clawed frog (Xenopus laevis)	Amphibia	Xl.2738²	Xenopus laevis transcribed sequence with weak similarity more	73.78(n)		CA789644.1
zebrafish (Danio rerio)	Actinopterygii	rilpl1¹	Rab interacting lysosomal protein-like 1	70.72(n) 67.85(a)		780843 NM_001079664.1 NP_001073132.2
fruit fly (Drosophila melanogaster)	Insecta	CG11448¹	CG11448	55.4(n) 37.59(a)		31090 NM_130554.2 NP_569910.1
worm (Caenorhabditis elegans)	Secernentea	rilp-1¹	Protein RILP-1	43.56(n) 34.83(a)		175465 NM_171100.5 NP_741113.3

ENSEMBL Gene Tree for RILPL1 (if available)
TreeFam Gene Tree for RILPL1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RILPL1 gene

RILPL2² RILP²

RILPL1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs189317305^1,2		--	123955454(+)	`CTTCTA/CTACTC`	1	--	ds500¹		0	--	--	--	--
rs150912639^1,2		--	123955485(+)	`ATTCTA/GATGGG`	1	--	ds500¹		0	--	--	--	--
rs139455463^1,2		--	123955524(+)	`CGCAGC/GAATAA`	1	--	ds500¹		0	--	--	--	--
rs149678350^1,2		--	123955557(+)	`TTTTTC/TGGCAA`	1	--	ds500¹		0	--	--	--	--
rs182013112^1,2		--	123955637(+)	`TTTTTA/GGATGA`	1	--	ds500¹		0	--	--	--	--
rs147785194^1,2		--	123955654(+)	`ACTCTA/GTCGCC`	1	--	ds500¹		0	--	--	--	--
rs139567642^1,2		--	123955657(+)	`CTGTCA/GCCCAG`	1	--	ds500¹		0	--	--	--	--
rs185863983^1,2		--	123955818(+)	`TTCACC/TGTGTT`	1	--	ds500¹		0	--	--	--	--
rs11507744^1,2	C,F,	--	123955845(+)	`AACTCT/CGGACC`	1	--	ds500¹		7		NA	16
rs147619973^1,2		--	123956244(+)	`CGCCCC/TGCTTT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RILPL1 (123955909 - 124018265 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for RILPL1
1 CNV: 5313
2 Indels: 24885 71603

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RILPL1

DNA2.0 Custom Variant and Variant Library Synthesis for RILPL1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RILPL1 for disorders           About GeneDecksing

OMIM gene information: 614092    OMIM disorders: --

1 disease for RILPL1:    About MalaCards

neuronitis

Export disorders for RILPL1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RILPL1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RILPL1)

Utopia: connect your pdf to the dynamic
world of online information

A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. (PubMed id 14668488)^{1, 2, 3} Wang T.... Hong W. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
The finished DNA sequence of human chromosome 12. (PubMed id 16541075)² Scherer S.E.... Gibbs R.A. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 353116	HGNC: 26814	AceView: U1SNRNPBP	Ensembl:ENSG00000188026	euGenes: HUgn353116
ECgene: RILPL1	H-InvDB: RILPL1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RILPL1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RILPL1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RILPL1 gene:
Search GeneIP for patents involving RILPL1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		Browse OriGene shRNA RFPs
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RILPL1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RILPL1
	OriGene Protein Over-expression Lysate for RILPL1		Browse OriGene Fluorogenic Cell Assay Kits
	Browse OriGene siRNAs		OriGene 3'-UTR Clone for RILPL1
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RILPL1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RILPL1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for RILPL1		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for RILPL1		OriGene Custom Protein Services for RILPL1
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RILPL1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RILPL1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RILPL1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RILPL1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RILPL1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RILPL1

	GenScript Custom Purified and Recombinant Proteins Services for RILPL1		GenScript cDNA clones with any tag delivered in your preferred vector for RILPL1
	GenScript Custom Assay Services for RILPL1		GenScript Custom Superior Antibodies Services for RILPL1
	GenScript Custom overexpressing Cell Line Services for RILPL1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in RILPL1 promoter
	Search Chromatin IP Primers for RILPL1
	RT² qPCR Primer Assay in human, mouse, rat RILPL1
	Search GNC Networks for RILPL1
	SABiosciences Custom PCR Arrays for RILPL1

Search Tocris compounds for RILPL1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	RILPL1 antibodies
	RILPL1 proteins
	RILPL1 lysates

	Search for Antibodies for RILPL1 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for RILPL1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

RILPL1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RILPL1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RILPL1

	SwitchGear 3'UTR luciferase reporter plasmids for RILPL1
	SwitchGear Promoter luciferase reporter plasmids for RILPL1

ThermoFisher Antibodies for RILPL1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RILPL1

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes RILPL1 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

RILPL1 Gene

Rab interacting lysosomal protein-like 1

Aliases
for RILPL1 gene

Summaries
for RILPL1 gene

Genomic Views
for RILPL1 gene

Proteins
for RILPL1 gene

Protein Domains /
Families
for RILPL1 gene

Function
for RILPL1 gene

Pathways & Interactions
for RILPL1 gene

Drugs & Compounds
for RILPL1 gene

Transcripts
for RILPL1 gene

Expression
for RILPL1 gene

Orthologs
for RILPL1 gene

Paralogs
for RILPL1 gene

Genomic Variants
for RILPL1 gene

Disorders / Diseases
for RILPL1 gene

Publications
for RILPL1 gene

External Searches for RILPL1 gene

Genome Databases showing RILPL1 gene

Other Databases showing RILPL1 gene

Specialized Databases showing RILPL1 gene

Intellectual Property
for RILPL1 gene

Products
for RILPL1 gene

View Random Gene

Advanced Search

Export list of displayed genes

RILPL1 Gene

Rab interacting lysosomal protein-like 1

Aliasesfor RILPL1 gene

Summariesfor RILPL1 gene

Genomic Viewsfor RILPL1 gene

Proteinsfor RILPL1 gene

Protein Domains /Familiesfor RILPL1 gene

Functionfor RILPL1 gene

Pathways & Interactionsfor RILPL1 gene

Drugs & Compoundsfor RILPL1 gene

Transcriptsfor RILPL1 gene

Expression for RILPL1 gene

Orthologsfor RILPL1 gene

Paralogsfor RILPL1 gene

Genomic Variantsfor RILPL1 gene

Disorders / Diseasesfor RILPL1 gene

Publicationsfor RILPL1 gene

External Searches for RILPL1 gene

Genome Databases showing RILPL1 gene

Other Databases showing RILPL1 gene

Specialized Databases showing RILPL1 gene

Intellectual Propertyfor RILPL1 gene

Productsfor RILPL1 gene

View Random Gene

Aliases
for RILPL1 gene

Summaries
for RILPL1 gene

Genomic Views
for RILPL1 gene

Proteins
for RILPL1 gene

Protein Domains /
Families
for RILPL1 gene

Function
for RILPL1 gene

Pathways & Interactions
for RILPL1 gene

Drugs & Compounds
for RILPL1 gene

Transcripts
for RILPL1 gene

Expression
for RILPL1 gene

Orthologs
for RILPL1 gene

Paralogs
for RILPL1 gene

Genomic Variants
for RILPL1 gene

Disorders / Diseases
for RILPL1 gene

Publications
for RILPL1 gene

Intellectual Property
for RILPL1 gene

Products
for RILPL1 gene