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Aliases for RIIAD1 Gene

Aliases for RIIAD1 Gene

  • Regulatory Subunit Of Type II PKA R-Subunit (RIIa) Domain Containing 1 2 3
  • C1orf230 3 4
  • RIIa Domain-Containing Protein ENSP00000357824 3
  • RIIa Domain-Containing Protein C1orf230 3
  • Chromosome 1 Open Reading Frame 230 2
  • Non-Protein Coding RNA 166 2
  • NCRNA00166 3

External Ids for RIIAD1 Gene

Previous HGNC Symbols for RIIAD1 Gene

  • NCRNA00166
  • C1orf230

Previous GeneCards Identifiers for RIIAD1 Gene

  • GC01P151684

Summaries for RIIAD1 Gene

GeneCards Summary for RIIAD1 Gene

RIIAD1 (Regulatory Subunit Of Type II PKA R-Subunit (RIIa) Domain Containing 1) is a Protein Coding gene. Among its related pathways are Endothelin.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RIIAD1 Gene

Genomics for RIIAD1 Gene

Genomic Location for RIIAD1 Gene

Chromosome:
1
Start:
151,710,433 bp from pter
End:
151,729,805 bp from pter
Size:
19,373 bases
Orientation:
Plus strand

Genomic View for RIIAD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RIIAD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RIIAD1 Gene

No data available for Regulatory Elements for RIIAD1 Gene

Proteins for RIIAD1 Gene

  • Protein details for RIIAD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNX1-RIAD1_HUMAN
    Recommended name:
    RIIa domain-containing protein 1
    Protein Accession:
    A6NNX1

    Protein attributes for RIIAD1 Gene

    Size:
    92 amino acids
    Molecular mass:
    10810 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RIIAD1 Gene

Proteomics data for RIIAD1 Gene at MOPED

Post-translational modifications for RIIAD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RIIAD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RIIAD1 Gene

Domains & Families for RIIAD1 Gene

Protein Domains for RIIAD1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for RIIAD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NNX1

UniProtKB/Swiss-Prot:

RIAD1_HUMAN :
  • Contains 1 RIIa domain.
Domain:
  • Contains 1 RIIa domain.
genes like me logo Genes that share domains with RIIAD1: view

No data available for Gene Families for RIIAD1 Gene

Function for RIIAD1 Gene

Gene Ontology (GO) - Molecular Function for RIIAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005516 calmodulin binding IBA --
genes like me logo Genes that share ontologies with RIIAD1: view

Animal Model Products

miRNA for RIIAD1 Gene

miRTarBase miRNAs that target RIIAD1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RIIAD1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for RIIAD1 Gene

Localization for RIIAD1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RIIAD1 Gene

Pathways & Interactions for RIIAD1 Gene

SuperPathways for RIIAD1 Gene

Superpath Contained pathways
1 Endothelin
genes like me logo Genes that share pathways with RIIAD1: view

Pathways by source for RIIAD1 Gene

1 BioSystems pathway for RIIAD1 Gene

Interacting Proteins for RIIAD1 Gene

Gene Ontology (GO) - Biological Process for RIIAD1 Gene

None

No data available for SIGNOR curated interactions for RIIAD1 Gene

Drugs & Compounds for RIIAD1 Gene

No Compound Related Data Available

Transcripts for RIIAD1 Gene

mRNA/cDNA for RIIAD1 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(17) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RIIAD1 Gene

Regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RIIAD1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RIIAD1 Gene

No ASD Table

Relevant External Links for RIIAD1 Gene

GeneLoc Exon Structure for
RIIAD1
ECgene alternative splicing isoforms for
RIIAD1

Expression for RIIAD1 Gene

mRNA expression in normal human tissues for RIIAD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RIIAD1 Gene

This gene is overexpressed in Pituitary (x6.3), Brain - Amygdala (x6.1), and Brain - Nucleus accumbens (basal ganglia) (x4.2).

Protein differential expression in normal tissues from HIPED for RIIAD1 Gene

This gene is overexpressed in Kidney (31.8), Lymph node (12.2), and Gallbladder (9.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RIIAD1 Gene



SOURCE GeneReport for Unigene cluster for RIIAD1 Gene Hs.297967

genes like me logo Genes that share expression patterns with RIIAD1: view

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RIIAD1 Gene

Orthologs for RIIAD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RIIAD1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RIIAD1 35
  • 85.87 (n)
  • 78.26 (a)
RIIAD1 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RIIAD1 35
  • 88.77 (n)
  • 85.71 (a)
RIIAD1 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Riiad1 35
  • 77.54 (n)
  • 77.17 (a)
Riiad1 16
Riiad1 36
  • 60 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RIIAD1 35
  • 98.91 (n)
  • 97.83 (a)
RIIAD1 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Riiad1 35
  • 77.17 (n)
  • 79.35 (a)
oppossum
(Monodelphis domestica)
Mammalia RIIAD1 36
  • 39 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC100536995 35
  • 60.68 (n)
  • 61.54 (a)
RIIAD1 36
  • 57 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 46 (a)
OneToOne
Species with no ortholog for RIIAD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RIIAD1 Gene

ENSEMBL:
Gene Tree for RIIAD1 (if available)
TreeFam:
Gene Tree for RIIAD1 (if available)

Paralogs for RIIAD1 Gene

No data available for Paralogs for RIIAD1 Gene

Variants for RIIAD1 Gene

Sequence variations from dbSNP and Humsavar for RIIAD1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs554907050 -- 151,721,575(+) GACCC(C/T)GGGGC reference, synonymous-codon
rs554682453 -- 151,726,267(+) CTCTT(C/T)AGCAC intron-variant
rs554213124 -- 151,728,524(+) TGGAG(A/G)GGAGG intron-variant
rs553755214 -- 151,725,449(+) GTTGC(C/T)TTTTT intron-variant
rs553178584 -- 151,724,334(+) GTTTA(G/T)TGTTT intron-variant

Variation tolerance for RIIAD1 Gene

Gene Damage Index Score: 1.71; 32.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RIIAD1 Gene

HapMap Linkage Disequilibrium report
RIIAD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RIIAD1 Gene

Disorders for RIIAD1 Gene

Relevant External Links for RIIAD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RIIAD1
genes like me logo Genes that share disorders with RIIAD1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RIIAD1 Gene

Publications for RIIAD1 Gene

  1. Uncoupling of bait-protein expression from the prey protein environment adds versatility for cell and tissue interaction proteomics and reveals a complex of CARP-1 and the PKA Cbeta1 subunit. (PMID: 20564261) Erlbruch A. … Bossemeyer D. (Proteomics 2010) 67
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 67

Products for RIIAD1 Gene

Sources for RIIAD1 Gene

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