Aliases for RICTOR Gene
Aliases for RICTOR Gene
External Ids for RICTOR Gene
- HGNC: 28611
- Entrez Gene: 253260
- Ensembl: ENSG00000164327
- OMIM: 609022
- UniProtKB: Q6R327
Previous GeneCards Identifiers for RICTOR Gene
- GC05M038977
Summaries for RICTOR Gene
-
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RICTOR Gene
RICTOR (RPTOR Independent Companion Of MTOR Complex 2) is a Protein Coding gene. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include binding and ribosome binding.
UniProtKB/Swiss-Prot for RICTOR Gene
-
Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 Ser-473 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on Thr-308 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at Ser-422. mTORC2 also modulates the phosphorylation of PRKCA on Ser-657. Plays an essential role in embryonic growth and development.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RICTOR Gene
Genomics for RICTOR Gene
Regulatory Elements for RICTOR Gene
Enhancers for RICTOR Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around RICTOR on UCSC Golden Path with GeneCards custom track
Promoters for RICTOR Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around RICTOR on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the RICTOR gene promoter:
Regulatory Element Products
Genomic Location for RICTOR Gene
- Chromosome:
- 5
- Start:
- 38,937,919 bp from pter
- End:
- 39,074,419 bp from pter
- Size:
- 136,501 bases
- Orientation:
- Minus strand
Genomic View for RICTOR Gene
Genes around RICTOR on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5p13.1 by Ensembl
- 5p13.1 by Entrez Gene
- 5p13.1 by HGNC
RICTOR Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RICTOR Gene
Proteins for RICTOR Gene
-
Protein details for RICTOR Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6R327-RICTR_HUMAN
- Recommended name:
- Rapamycin-insensitive companion of mTOR
- Protein Accession:
- Q6R327
- B2RNX0
- B7ZMF7
- Q68DT5
- Q86UB7
- Q8N3A0
- Q8NCM6
Protein attributes for RICTOR Gene
- Size:
- 1708 amino acids
- Molecular mass:
- 192218 Da
- Quaternary structure:
-
- Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to MTOR and PRR5 within the TORC2 complex. Interacts with CCDC28B and NBN. May interact with PRR5L.
- SequenceCaution:
-
- Sequence=CAH18135.1; Type=Miscellaneous discrepancy; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
Protein Expression for RICTOR Gene
Post-translational modifications for RICTOR Gene
- Phosphorylated by MTOR; when part of mTORC2. Phosphorylated at Thr-1135 by RPS6KB1; phosphorylation of RICTOR inhibits mTORC2 and AKT1 signaling.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for RICTOR Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for RICTOR
- R&D Systems Antibodies for RICTOR (Rictor)
- Cell Signaling Technology (CST) Antibodies for RICTOR (RICTOR)
- Novus Biologicals Antibodies for RICTOR
- Invitrogen Antibodies for RICTOR
- antibodies-online Antibodies for RICTOR: See all 139
- GeneTex RICTOR antibody for RICTOR
-
Santa Cruz Biotechnology (SCBT) Antibodies for RICTOR
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RICTOR
- Origene Custom Protein Services for RICTOR
- Search GeneTex for Proteins for RICTOR
Assay Products
- antibodies-online Kits for RICTOR: See all 3
No data available for DME Specific Peptides for RICTOR Gene
Domains & Families for RICTOR Gene
Protein Domains for RICTOR Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RICTOR Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6R327- Family:
-
- Belongs to the RICTOR family.
No data available for Gene Families for RICTOR Gene
Function for RICTOR Gene
Molecular function for RICTOR Gene
- UniProtKB/Swiss-Prot Function:
- Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 Ser-473 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on Thr-308 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at Ser-422. mTORC2 also modulates the phosphorylation of PRKCA on Ser-657. Plays an essential role in embryonic growth and development.
Phenotypes for RICTOR Gene
- MGI mutant phenotypes for RICTOR:
-
inferred from 8 alleles
- cellular phenotype
- mortality/aging
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- liver/biliary system phenotype
- immune system phenotype
- cardiovascular system phenotype
- growth/size/body region phenotype
- hematopoietic system phenotype
- tumorigenesis
- homeostasis/metabolism phenotype
- embryo phenotype
- muscle phenotype
- skeleton phenotype
- renal/urinary system phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for RICTOR:
-
- Increased vaccinia virus (VACV) infection
- Decreased POU5F1-GFP protein expression
- Decreased shRNA abundance (Z-score < -2)
- Decreased cell migration
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Increased shRNA abundance (Z-score > 2)
- Decreased OCT4 protein expression
- Decreased NANOG protein expression
- Increased cell migration
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for RICTOR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RICTOR gene
- Search ViGene Biosciences for RICTOR
CRISPR Products
-
OriGene CRISPR knockouts for RICTOR
-
Santa Cruz Biotechnology (SCBT) CRISPR for RICTOR
- GenScript: Design CRISPR guide RNA sequences for RICTOR
miRNA for RICTOR Gene
- miRTarBase miRNAs that target RICTOR
-
- hsa-mir-218-5p (MIRT006105)
- hsa-mir-335-5p (MIRT018260)
- hsa-mir-155-5p (MIRT020841)
- hsa-mir-31-3p (MIRT038935)
- hsa-mir-18a-5p (MIRT050668)
- hsa-mir-34a-5p (MIRT054810)
- hsa-mir-6747-5p (MIRT166223)
- hsa-mir-3124-3p (MIRT391490)
- hsa-let-7c-5p (MIRT437348)
- hsa-mir-16-5p (MIRT437349)
- hsa-mir-142-3p (MIRT439769)
- hsa-mir-4665-5p (MIRT469189)
- hsa-mir-1275 (MIRT469190)
- hsa-mir-4472 (MIRT469191)
- hsa-mir-4447 (MIRT469192)
- hsa-mir-6769b-5p (MIRT469193)
- hsa-mir-6769a-5p (MIRT469194)
- hsa-mir-92a-2-5p (MIRT469195)
- hsa-mir-654-5p (MIRT469196)
- hsa-mir-541-3p (MIRT469197)
- hsa-mir-7110-5p (MIRT469198)
- hsa-mir-6842-5p (MIRT469199)
- hsa-mir-6752-5p (MIRT469200)
- hsa-mir-5010-5p (MIRT469201)
- hsa-mir-4525 (MIRT469202)
- hsa-mir-7111-5p (MIRT469203)
- hsa-mir-6870-5p (MIRT469204)
- hsa-mir-4723-5p (MIRT469205)
- hsa-mir-5698 (MIRT469206)
- hsa-mir-6825-5p (MIRT469207)
- hsa-mir-625-5p (MIRT469208)
- hsa-mir-6883-5p (MIRT469209)
- hsa-mir-6785-5p (MIRT469210)
- hsa-mir-4728-5p (MIRT469211)
- hsa-mir-149-3p (MIRT469212)
- hsa-mir-8069 (MIRT469213)
- hsa-mir-8062 (MIRT469214)
- hsa-mir-8079 (MIRT469215)
- hsa-mir-1245a (MIRT469216)
- hsa-mir-6841-5p (MIRT469217)
- hsa-mir-6732-5p (MIRT469218)
- hsa-mir-384 (MIRT654255)
- hsa-mir-3685 (MIRT654256)
- hsa-mir-6509-5p (MIRT654257)
- hsa-mir-202-5p (MIRT654258)
- hsa-mir-337-3p (MIRT654259)
- hsa-mir-3160-5p (MIRT654260)
- hsa-mir-3927-5p (MIRT654261)
- hsa-mir-500b-5p (MIRT654262)
- hsa-mir-362-5p (MIRT654263)
miRNA Products
- Search ViGene Biosciences for RICTOR
Inhibitory RNA Products
- Origene RNAi, shRNA, mouse_rna, and siRNA products in human, mouse, rat for RICTOR
- Browse OriGene Inhibitory RNA Products For RICTOR
-
ViGene Biosciences ready-to-package AAV shRNAs for RICTOR gene
Clone Products
- OriGene clones in human for RICTOR
- OriGene ORF clones in human for RICTOR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for RICTOR
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for RICTOR gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RICTOR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RICTOR gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RICTOR Gene
Localization for RICTOR Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| mitochondrion | 3 |
| nucleus | 3 |
| cytoskeleton | 2 |
| lysosome | 1 |
| plasma membrane | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RICTOR Gene
Pathways & Interactions for RICTOR Gene
More details on SuperPathways for RICTOR| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Interleukin-3, 5 and GM-CSF signaling |
.95
|
|
| 2 | PI3K events in ERBB4 signaling |
.82
|
|
| 3 | CD28 co-stimulation | ||
| 4 | Immune System |
.52
|
|
| 5 | Downstream signaling events of B Cell Receptor (BCR) |
Pathways by source for RICTOR Gene
1 GeneTex pathway for RICTOR Gene
1 Cell Signaling Technology pathway for RICTOR Gene
8 BioSystems pathways for RICTOR Gene
50 Reactome pathways for RICTOR Gene
1 KEGG pathway for RICTOR Gene
2 R&D Systems pathways for RICTOR Gene
1 Qiagen pathway for RICTOR Gene
Interacting Proteins for RICTOR Gene
Selected Interacting proteins:
Q6R327-RICTR_HUMAN
ENSP00000349959
for RICTOR Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001938 | positive regulation of endothelial cell proliferation | IEA | -- |
| GO:0007173 | epidermal growth factor receptor signaling pathway | TAS | -- |
| GO:0008543 | fibroblast growth factor receptor signaling pathway | TAS | -- |
| GO:0009790 | embryo development | IEA,ISS | -- |
| GO:0010468 | regulation of gene expression | IEA | -- |
Drugs & Compounds for RICTOR Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| OSI-027 | Pharma | inhibitor | MTORC1/ mTORC2 inhibitor, Kinase Inhibitors | 0 | ||
| AZD2014 | Pharma | Novel mTOR inhibitor | 0 | |||
| GDC-0349 | Pharma | MTOR inhibitor | 0 | |||
| GDC-0980 (RG7422) | Pharma | Class I PI3K inhibitor for PI3Kα/β/δ/γ | 0 | |||
| KU-0063794 | Pharma | MTORC1 and mTORC2 inhibitor, Selective mTOR inhibitor | 0 |
(11) ApexBio Compounds for RICTOR Gene
| Compound | Action | Cas Number |
|---|---|---|
| AZD2014 | Novel mTOR inhibitor | 1009298-59-2 |
| GDC-0349 | MTOR inhibitor | 1207360-89-1 |
| GDC-0980 (RG7422) | Class I PI3K inhibitor for PI3Kα/β/δ/γ | 1032754-93-0 |
| KU-0063794 | MTORC1 and mTORC2 inhibitor | 938440-64-3 |
| OSI-027 | MTORC1/ mTORC2 inhibitor | 936890-98-1 |
| Ridaforolimus (Deforolimus, MK-8669) | MTOR inhibitor | 572924-54-0 |
| WAY-600 | MTOR inhibitor | 1062159-35-6 |
| WYE-125132 (WYE-132) | ATP-competitive mTOR inhibitor, highly potent | 1144068-46-1 |
| WYE-354 | MTOR inhibitor,potent,ATP-competitive and cell-permeable | 1062169-56-5 |
| WYE-687 | MTOR inhibitor,ATP-competitive and selective | 1062161-90-3 |
| XL388 | MTOR inhibitor,highly potent and selective | 1251156-08-7 |
Drug Products
- ApexBio compounds for RICTOR
Transcripts for RICTOR Gene
mRNA/cDNA for RICTOR Gene
- (7) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (166) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RICTOR Gene
CRISPR Products
-
OriGene CRISPR knockouts for RICTOR
-
Santa Cruz Biotechnology (SCBT) CRISPR for RICTOR
- GenScript: Design CRISPR guide RNA sequences for RICTOR
miRNA Products
- Search ViGene Biosciences for RICTOR
Inhibitory RNA Products
- Origene RNAi, shRNA, mouse_rna, and siRNA products in human, mouse, rat for RICTOR
- Browse OriGene Inhibitory RNA Products For RICTOR
-
ViGene Biosciences ready-to-package AAV shRNAs for RICTOR gene
Clone Products
- OriGene clones in human for RICTOR
- OriGene ORF clones in human for RICTOR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for RICTOR
Flow Cytometry Products
Expression for RICTOR Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
This gene is overexpressed in Tlymphocyte (42.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RICTOR Gene
SOURCE GeneReport for Unigene cluster for RICTOR Gene Hs.407926
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for RICTOR
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RICTOR Gene
Orthologs for RICTOR Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | RICTOR 35 |
|
||
| RICTOR 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | RICTOR 35 |
|
||
| RICTOR 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Rictor 35 |
|
||
| Rictor 16 |
|
||||
| Rictor 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | RICTOR 35 |
|
||
| RICTOR 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Rictor 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | RICTOR 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | RICTOR 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RICTOR 35 |
|
||
| RICTOR 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | RICTOR 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rictor 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | rictorb 35 |
|
||
| RICTOR (3 of 3) 36 |
|
OneToMany | |||
| rictora 36 |
|
OneToMany | |||
| rictorb 36 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | rictor 36 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | rict-1 36 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | TSC11 36 |
|
OneToOne | |
| TSC11 38 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2872 36 |
|
OneToOne |
- Species with no ortholog for RICTOR:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for RICTOR Gene
No data available for Paralogs for RICTOR Gene
Variants for RICTOR Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs2043112 | - | 38,955,694(-) | CAACT(A/C/T)CAAAT | reference, missense | |
| rs961115 | -- | 39,070,831(-) | GCTTC(C/T)TCTCG | intron-variant | |
| rs2887112 | -- | 39,052,218(-) | AAAAA(A/T)TTTTT | intron-variant | |
| rs1055480 | -- | 39,041,840(+) | gaggc(C/T)gatag | intron-variant | |
| rs1070244 | -- | 39,037,587(-) | ctttt(C/T)ttctt | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv820160 | CNV | Loss | 19587683 |
| nsv529023 | CNV | Loss | 19592680 |
| nsv4802 | CNV | Insertion | 18451855 |
| esv1576101 | CNV | Insertion | 17803354 |
| nsv528773 | CNV | Loss | 19592680 |
| nsv519072 | CNV | Loss | 19592680 |
| nsv818346 | CNV | Loss | 17921354 |
| nsv4803 | CNV | Loss | 18451855 |
| esv2730111 | CNV | Deletion | 23290073 |
| esv24079 | CNV | Loss | 19812545 |
Residual Variation Intolerance Score:
1.11% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
11.84;
93.46% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RICTOR Gene
Disorders for RICTOR Gene
Relevant External Links for RICTOR
No disorders were found for RICTOR Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RICTOR Gene
Publications for RICTOR Gene
- mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling. (PMID: 19995915) Julien L.A. … Roux P.P. (Mol. Cell. Biol. 2010) 3 4 23 67
- mTOR complex-2 activates ENaC by phosphorylating SGK1. (PMID: 20338997) Lu M. … Pearce D. (J. Am. Soc. Nephrol. 2010) 3 23
- Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin. (PMID: 19114562) Toschi A. … Foster D.A. (Mol. Cell. Biol. 2009) 3 23
- Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility. (PMID: 19724909) Gulati N. … Jhanwar-Uniyal M. (Int. J. Oncol. 2009) 3 23
- Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer. (PMID: 19934294) Gulhati P. … Evers B.M. (Clin. Cancer Res. 2009) 3 23
Products for RICTOR Gene
- R&D Systems Antibodies for RICTOR (Rictor)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse ELISpot/FluoroSpot Kits and Development Modules
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- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RICTOR
- Origene Custom Protein Services for RICTOR
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for RICTOR
- Browse OriGene Inhibitory RNA Products For RICTOR
- OriGene qPCR primer pairs for RICTOR
- OriGene CRISPR knockouts for RICTOR
- OriGene clones in human for RICTOR
- OriGene ORF clones in human for RICTOR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for RICTOR
- GenScript Custom Assay Services for RICTOR
- GenScript Custom overexpressing Cell Line Services for RICTOR
- GenScript: Design CRISPR guide RNA sequences for RICTOR
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for RICTOR
- Cell Signaling Technology (CST) Antibodies for RICTOR (RICTOR)
- Search for Antibodies & Assays
- Novus Biologicals Antibodies for RICTOR
- Novus Biologicals proteins and lysates for RICTOR
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for RICTOR
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for RICTOR
- Addgene plasmids for RICTOR
- antibodies-online Antibodies for RICTOR: See all 139
- antibodies-online Kits for RICTOR: See all 3
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex RICTOR antibody for RICTOR
- Search GeneTex for Proteins for RICTOR
- ViGene Biosciences adenoviral particle packaged cDNA for RICTOR gene
- ViGene Biosciences lentiviral particle packaged cDNA for RICTOR gene
- ViGene Biosciences lentiviral particle packaged cDNA for RICTOR gene
- ViGene Biosciences ready-to-package AAV shRNAs for RICTOR gene
- ViGene Biosciences ready-to-package AAV shRNAs for RICTOR gene
- ViGene Biosciences ready-to-package AAV shRNAs for RICTOR gene
- Search ViGene Biosciences for RICTOR
- Search ViGene Biosciences for RICTOR
- Santa Cruz Biotechnology (SCBT) Antibodies for RICTOR
- Search Santa Cruz Biotechnology (SCBT) for RICTOR siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RICTOR
Sources for RICTOR Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
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