Aliases for RIC3 Gene
- RIC3 Acetylcholine Receptor Chaperone 2 3 5
- Resistant To Inhibitor Of Cholinesterase 3 3 4
- Resistance To Inhibitors Of Cholinesterase 3 Homolog (C. Elegans) 2
- Resistance To Inhibitors Of Cholinesterase 3-Like Protein 3
- Resistance To Inhibitors Of Cholinesterase 3 Homolog 3
- Protein RIC-3 3
- AYST720 3
- PRO1385 3
External Ids for RIC3 Gene
Previous GeneCards Identifiers for RIC3 Gene
The protein encoded by this gene promotes functional expression of homomeric nicotinic acetylcholine receptors at the cell surface. It enhances currents generated by these receptors by expediting receptor transport to the cell surface and by increasing receptor number. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for RIC3 Gene
RIC3 (RIC3 Acetylcholine Receptor Chaperone) is a Protein Coding gene. GO annotations related to this gene include protein binding involved in protein folding and acetylcholine receptor binding.
UniProtKB/Swiss-Prot for RIC3 Gene
Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.