Aliases for RIC1 Gene
External Ids for RIC1 Gene
Previous HGNC Symbols for RIC1 Gene
GeneCards Summary for RIC1 Gene
RIC1 (RIC1 Homolog, RAB6A GEF Complex Partner 1) is a Protein Coding gene. Among its related pathways are Golgi-to-ER retrograde transport and Retrograde transport at the Trans-Golgi-Network. GO annotations related to this gene include Rab GTPase binding and Rab guanyl-nucleotide exchange factor activity.
UniProtKB/Swiss-Prot for RIC1 Gene
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1.