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Aliases for RIBC1 Gene

Aliases for RIBC1 Gene

  • RIB43A Domain With Coiled-Coils 1 2 3 5
  • 2610028I09Rik 3

External Ids for RIBC1 Gene

Previous GeneCards Identifiers for RIBC1 Gene

  • GC0XP053332
  • GC0XP053466
  • GC0XP050507

Summaries for RIBC1 Gene

GeneCards Summary for RIBC1 Gene

RIBC1 (RIB43A Domain With Coiled-Coils 1) is a Protein Coding gene. An important paralog of this gene is RIBC2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RIBC1 Gene

Genomics for RIBC1 Gene

Regulatory Elements for RIBC1 Gene

Enhancers for RIBC1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RIBC1 on UCSC Golden Path with GeneCards custom track

Promoters for RIBC1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RIBC1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RIBC1 Gene

Chromosome:
X
Start:
53,422,690 bp from pter
End:
53,431,120 bp from pter
Size:
8,431 bases
Orientation:
Plus strand

Genomic View for RIBC1 Gene

Genes around RIBC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RIBC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RIBC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RIBC1 Gene

Proteins for RIBC1 Gene

  • Protein details for RIBC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N443-RIBC1_HUMAN
    Recommended name:
    RIB43A-like with coiled-coils protein 1
    Protein Accession:
    Q8N443
    Secondary Accessions:
    • B4E297
    • E9PDU2
    • Q5H931
    • Q96A80

    Protein attributes for RIBC1 Gene

    Size:
    379 amino acids
    Molecular mass:
    44015 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for RIBC1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RIBC1 Gene

Proteomics data for RIBC1 Gene at MOPED

Post-translational modifications for RIBC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RIBC1 Gene

No data available for DME Specific Peptides for RIBC1 Gene

Domains & Families for RIBC1 Gene

Protein Domains for RIBC1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for RIBC1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N443

UniProtKB/Swiss-Prot:

RIBC1_HUMAN :
  • Belongs to the RIB43A family.
Family:
  • Belongs to the RIB43A family.
genes like me logo Genes that share domains with RIBC1: view

No data available for Gene Families for RIBC1 Gene

Function for RIBC1 Gene

genes like me logo Genes that share phenotypes with RIBC1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RIBC1 Gene

Localization for RIBC1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RIBC1 Gene COMPARTMENTS Subcellular localization image for RIBC1 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RIBC1 Gene

Pathways & Interactions for RIBC1 Gene

SuperPathways for RIBC1 Gene

No Data Available

Interacting Proteins for RIBC1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000364476%0d%0a9606.ENSP00000384015%0d%0a9606.ENSP00000385616%0d%0a
Selected Interacting proteins: ENSP00000364476 Q8N443-RIBC1_HUMAN for RIBC1 Gene via STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for RIBC1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RIBC1 Gene

Drugs & Compounds for RIBC1 Gene

No Compound Related Data Available

Transcripts for RIBC1 Gene

Unigene Clusters for RIBC1 Gene

RIB43A domain with coiled-coils 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RIBC1 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11
SP1: - - - -
SP2: - - - - - - -
SP3: - -
SP4: - - - -
SP5: - - -
SP6: -
SP7: - -

Relevant External Links for RIBC1 Gene

GeneLoc Exon Structure for
RIBC1
ECgene alternative splicing isoforms for
RIBC1

Expression for RIBC1 Gene

mRNA expression in normal human tissues for RIBC1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RIBC1 Gene

This gene is overexpressed in Testis (x16.3).

Protein differential expression in normal tissues from HIPED for RIBC1 Gene

This gene is overexpressed in Heart (38.0) and Testis (31.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RIBC1 Gene



SOURCE GeneReport for Unigene cluster for RIBC1 Gene Hs.351743

genes like me logo Genes that share expression patterns with RIBC1: view

Protein tissue co-expression partners for RIBC1 Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for RIBC1 Gene

Orthologs for RIBC1 Gene

This gene was present in the common ancestor of animals.

Orthologs for RIBC1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RIBC1 35
  • 80.39 (n)
  • 69.13 (a)
RIBC1 36
  • 69 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RIBC1 35
  • 81.97 (n)
  • 72.3 (a)
RIBC1 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ribc1 35
  • 73.63 (n)
  • 66.4 (a)
Ribc1 16
Ribc1 36
  • 66 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RIBC1 35
  • 99.47 (n)
  • 99.74 (a)
RIBC1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ribc1 35
  • 74.62 (n)
  • 68.44 (a)
oppossum
(Monodelphis domestica)
Mammalia RIBC1 36
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RIBC1 36
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RIBC1 36
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ribc1 35
  • 53.3 (n)
  • 41.95 (a)
zebrafish
(Danio rerio)
Actinopterygii ribc1 35
  • 48.4 (n)
  • 36.36 (a)
ribc1 36
  • 33 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG7264 36
  • 24 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 36 (a)
OneToOne
Species with no ortholog for RIBC1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RIBC1 Gene

ENSEMBL:
Gene Tree for RIBC1 (if available)
TreeFam:
Gene Tree for RIBC1 (if available)

Paralogs for RIBC1 Gene

Paralogs for RIBC1 Gene

(1) SIMAP similar genes for RIBC1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RIBC1: view

Variants for RIBC1 Gene

Sequence variations from dbSNP and Humsavar for RIBC1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1264012 -- 53,427,432(+) CCAGC(C/T)GACAA intron-variant
rs1264013 -- 53,430,674(+) CAGAC(C/T)ATGAG reference, synonymous-codon
rs4830346 -- 53,426,126(+) cagag(A/C)tggag intron-variant
rs5978132 -- 53,426,253(+) TGGGC(C/T)ATTCC intron-variant
rs12392275 -- 53,426,435(-) GCCAC(A/C/G/T)TCACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RIBC1 Gene

Variant ID Type Subtype PubMed ID
nsv435891 CNV Deletion 17901297
esv2740175 CNV Deletion 23290073
nsv6908 CNV Insertion 18451855

Variation tolerance for RIBC1 Gene

Residual Variation Intolerance Score: 38.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.23; 5.21% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RIBC1 Gene

Disorders for RIBC1 Gene

Relevant External Links for RIBC1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RIBC1

No disorders were found for RIBC1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RIBC1 Gene

Publications for RIBC1 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation. (PMID: 18252223) Froyen G. … Gecz J. (Am. J. Hum. Genet. 2008) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. A transcript finishing initiative for closing gaps in the human transcriptome. (PMID: 15197164) Sogayar M.C. … Zanette D.L. (Genome Res. 2004) 3

Products for RIBC1 Gene

Sources for RIBC1 Gene

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