RHOXF2B Gene
protein-coding GIFtS: 33
GCID: GC0XM119206
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Rhox homeobox family, member 2B
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Aliases
for RHOXF2B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rhox Homeobox Family, Member 2B1 2 | | Rhox Homeobox Family Member 2B2 |
Export aliases for RHOXF2B gene to outside databasesPrevious GC identifer: GC0XM119091 |
Summaries
for RHOXF2B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RHOXF2B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_018934.1 NC_000023.10 NT_011786.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RHOXF2B gene promoter:
POU6F1 (c2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for RHOXF2B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHOXF2B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq24 Ensembl cytogenetic band: Xq24 HGNC cytogenetic band: Xq24RHOXF2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM119206: view genomic region
(about GC identifiers)
Start:
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119,205,848 bp from pter |
End:
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119,211,707 bp from pter |
Size:
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5,860 bases |
Orientation:
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minus strand |
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Proteins
for RHOXF2B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RHF2B_HUMAN, P0C7M4 (See
protein sequence)Recommended Name: Rhox homeobox family member 2B Size: 288 amino acids; 31637 Da
Subcellular location: Nucleus (By similarity)Explore the universe of human proteins at neXtProt for RHOXF2B: NX_P0C7M4
RHOXF2B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001093155.1
ENSEMBL proteins: ENSP00000360455
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
RHOXF2B for ontologies About GeneDecksing
RHOXF2B Antibody Products:
Assay Products for RHOXF2B: |
Protein
Domains /
Families
for RHOXF2B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RHOXF2B for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P0C7M4ProtoNet protein and cluster: P0C7M4 UniProtKB/Swiss-Prot: RHF2B_HUMAN, P0C7M4Similarity: Belongs to the paired-like homeobox family. PEPP subfamilySimilarity: Contains 1 homeobox DNA-binding domain |
Function
for RHOXF2B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHOXF2B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHOXF2B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RHOXF2B (NM_001099685) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RHOXF2B | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RHOXF2B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHOXF2B |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0043565 | sequence-specific DNA binding |
IEA | -- |
RHOXF2B for ontologies About GeneDecksing
|
Pathways & Interactions
for RHOXF2B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RHOXF2B
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for RHOXF2B (ENSP000003604554) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for RHOXF2B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RHOXF2B
Search CenterWatch for drugs/clinical trials and news about RHOXF2B / RHF2B
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Transcripts
for RHOXF2B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RHOXF2B gene: NM_001099685.1 Unigene Cluster for RHOXF2B: Rhox homeobox family, member 2B Hs.196956 [show with all ESTs]Unigene Representative Sequence: NM_0010996851 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000371402(uc004esj.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHOXF2B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHOXF2B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RHOXF2B (NM_001099685) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RHOXF2B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RHOXF2B |
2 DOTS entries: DT.100728321 DT.306192
GeneLoc Exon Structure
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Expression
for RHOXF2B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RHOXF2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RHOXF2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RHOXF2B
SOURCE GeneReport for Unigene cluster: Hs.196956
SABiosciences Custom PCR Arrays for RHOXF2B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RHOXF2B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RHOXF2B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RHOXF2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RHOXF2B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHOXF2B |
Orthologs
for RHOXF2B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for RHOXF2B (if available)
TreeFam Gene Tree for RHOXF2B (if available) |
Paralogs
for RHOXF2B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RHOXF2B gene
- RHOXF21 2 RHOXF12 ESX12
1 SIMAP similar gene for RHOXF2B using alignment to 1 protein entry: RHF2B_HUMAN:RHOXF2
RHOXF2B for paralogs About GeneDecksing
|
Genomic Variants
for RHOXF2B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RHOXF2B (119205848 - 119211707 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for RHOXF2B
1 CNV: 4167
2 Indels: 33488 33489
1 Inversion: 37346 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for RHOXF2B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for RHOXF2B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RHOXF2B gene integrated from 9 sources:
(articles sorted by number of sources associating them with RHOXF2B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for RHOXF2B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing RHOXF2B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing RHOXF2B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RHOXF2B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RHOXF2B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for RHOXF2B gene:
Search GeneIP for patents involving RHOXF2B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RHOXF2B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RHOXF2B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RHOXF2B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RHOXF2B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RHOXF2B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHOXF2B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHOXF2B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RHOXF2B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RHOXF2B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHOXF2B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RHOXF2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RHOXF2B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RHOXF2B |
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 | | | RHOXF2B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHOXF2B |
|  |  |  | | | | Search ThermoFisher Antibodies for RHOXF2B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RHOXF2B |
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