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Aliases for RHOXF2B Gene

Aliases for RHOXF2B Gene

  • Rhox Homeobox Family, Member 2B 2 3

External Ids for RHOXF2B Gene

Summaries for RHOXF2B Gene

GeneCards Summary for RHOXF2B Gene

RHOXF2B (Rhox Homeobox Family, Member 2B) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is ESX1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RHOXF2B Gene

Genomics for RHOXF2B Gene

Genomic Location for RHOXF2B Gene

Start:
120,072,264 bp from pter
End:
120,077,742 bp from pter
Size:
5,479 bases
Orientation:
Minus strand

Genomic View for RHOXF2B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RHOXF2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RHOXF2B Gene

Regulatory Elements for RHOXF2B Gene

Transcription factor binding sites by QIAGEN in the RHOXF2B gene promoter:

Proteins for RHOXF2B Gene

  • Protein details for RHOXF2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7M4-RHF2B_HUMAN
    Recommended name:
    Rhox homeobox family member 2B
    Protein Accession:
    P0C7M4
    Secondary Accessions:

    Protein attributes for RHOXF2B Gene

    Size:
    288 amino acids
    Molecular mass:
    31637 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RHOXF2B Gene

Proteomics data for RHOXF2B Gene at MOPED

Post-translational modifications for RHOXF2B Gene

No Post-translational modifications

Other Protein References for RHOXF2B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RHOXF2B Gene

Domains for RHOXF2B Gene

Gene Families for RHOXF2B Gene

HGNC:
  • PRD :Homeoboxes / PRD class

Protein Domains for RHOXF2B Gene

UniProtKB/Swiss-Prot:

RHF2B_HUMAN
Domain:
  • Contains 1 homeobox DNA-binding domain.:
    • P0C7M4
Family:
  • Belongs to the paired-like homeobox family. PEPP subfamily.:
    • P0C7M4
genes like me logo Genes that share domains with RHOXF2B: view

Function for RHOXF2B Gene

Gene Ontology (GO) - Molecular Function for RHOXF2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with RHOXF2B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RHOXF2B Gene

Localization for RHOXF2B Gene

Subcellular locations from UniProtKB/Swiss-Prot for RHOXF2B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RHOXF2B Gene COMPARTMENTS Subcellular localization image for RHOXF2B gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

Gene Ontology (GO) - Cellular Components for RHOXF2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with RHOXF2B: view

Pathways for RHOXF2B Gene

SuperPathways for RHOXF2B Gene

No Data Available

Interacting Proteins for RHOXF2B Gene

Gene Ontology (GO) - Biological Process for RHOXF2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with RHOXF2B: view

No data available for Pathways by source for RHOXF2B Gene

Transcripts for RHOXF2B Gene

mRNA/cDNA for RHOXF2B Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RHOXF2B Gene

Rhox homeobox family, member 2B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RHOXF2B Gene

No ASD Table

Relevant External Links for RHOXF2B Gene

GeneLoc Exon Structure for
RHOXF2B
ECgene alternative splicing isoforms for
RHOXF2B

Expression for RHOXF2B Gene

mRNA expression in normal human tissues for RHOXF2B Gene

mRNA differential expression in normal tissues according to GTEx for RHOXF2B Gene

This gene is overexpressed in Testis (52.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RHOXF2B Gene

SOURCE GeneReport for Unigene cluster for RHOXF2B Gene Hs.196956

genes like me logo Genes that share expressions with RHOXF2B: view

Orthologs for RHOXF2B Gene

This gene was present in the common ancestor of mammals.

Orthologs for RHOXF2B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 82 (a)
ManyToMany
-- 37
  • 93 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 21 (a)
ManyToMany
-- 37
  • 21 (a)
ManyToMany
Species with no ortholog for RHOXF2B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RHOXF2B Gene

ENSEMBL:
Gene Tree for RHOXF2B (if available)
TreeFam:
Gene Tree for RHOXF2B (if available)

Paralogs for RHOXF2B Gene

Paralogs for RHOXF2B Gene

Selected SIMAP similar genes for RHOXF2B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RHOXF2B: view

Variants for RHOXF2B Gene

Sequence variations from dbSNP and Humsavar for RHOXF2B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs40781 -- 120,073,639(+) GTTTG(A/G)GAGAA intron-variant
rs40782 -- 120,074,279(-) GATAC(G/T)GAGAC intron-variant
rs40783 -- 120,074,674(+) AAGCT(A/G)TTAAG intron-variant
rs112514689 -- 120,078,252(+) TGAGA(C/G)AGTCT upstream-variant-2KB
rs139636887 -- 120,075,752(+) GCCAC(A/G)AAGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RHOXF2B Gene

Variant ID Type Subtype PubMed ID
dgv2469e1 CNV Complex 17122850
nsv7457 OTHER Inversion 18451855
nsv526653 CNV Gain 19592680
nsv9970 CNV Gain 18304495
nsv9971 CNV Gain 18304495

Relevant External Links for RHOXF2B Gene

HapMap Linkage Disequilibrium report
RHOXF2B

Disorders for RHOXF2B Gene

No disorders were found for RHOXF2B Gene.

No data available for UniProtKB/Swiss-Prot for RHOXF2B Gene

Publications for RHOXF2B Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4

Products for RHOXF2B Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate RHOXF2B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for RHOXF2B
    • Block miRNA regulation of RHOXF2B using miScript Target Protectors

    Sources for RHOXF2B Gene

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