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Aliases for RHOXF2 Gene

Aliases for RHOXF2 Gene

  • Rhox Homeobox Family, Member 2 2 3
  • PEPP2 3 4 6
  • Paired-Like Homeobox Protein PEPP-2 3 4
  • Cancer/Testis Antigen 107 2 3
  • Testis Homeobox Gene 1 3 4
  • THG1 3 4
  • Homeobox Protein From AL590526 3
  • Rhox Homeobox Family Member 2 3
  • PEPP Subfamily Gene 2 3
  • PEPP-2 3
  • CT107 3

External Ids for RHOXF2 Gene

Previous GeneCards Identifiers for RHOXF2 Gene

  • GC0XP119177
  • GC0XP119292
  • GC0XP108744

Summaries for RHOXF2 Gene

GeneCards Summary for RHOXF2 Gene

RHOXF2 (Rhox Homeobox Family, Member 2) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is ESX1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RHOXF2 Gene

Genomics for RHOXF2 Gene

Regulatory Elements for RHOXF2 Gene

Genomic Location for RHOXF2 Gene

120,158,526 bp from pter
120,164,039 bp from pter
5,514 bases
Plus strand

Genomic View for RHOXF2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RHOXF2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RHOXF2 Gene

Proteins for RHOXF2 Gene

  • Protein details for RHOXF2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Rhox homeobox family member 2
    Protein Accession:
    Secondary Accessions:
    • Q9BR00

    Protein attributes for RHOXF2 Gene

    288 amino acids
    Molecular mass:
    31692 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RHOXF2 Gene

Proteomics data for RHOXF2 Gene at MOPED

Post-translational modifications for RHOXF2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RHOXF2 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for RHOXF2 Gene

Domains for RHOXF2 Gene

Gene Families for RHOXF2 Gene

  • PRD :Homeoboxes / PRD class

Protein Domains for RHOXF2 Gene

Suggested Antigen Peptide Sequences for RHOXF2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9BQY4
  • Contains 1 homeobox DNA-binding domain.
  • Belongs to the paired-like homeobox family. PEPP subfamily.
genes like me logo Genes that share domains with RHOXF2: view

Function for RHOXF2 Gene

Gene Ontology (GO) - Molecular Function for RHOXF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0005515 protein binding IPI 16189514
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with RHOXF2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RHOXF2

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RHOXF2 Gene

Localization for RHOXF2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RHOXF2 Gene

Subcellular locations from

Jensen Localization Image for RHOXF2 Gene COMPARTMENTS Subcellular localization image for RHOXF2 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

Gene Ontology (GO) - Cellular Components for RHOXF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with RHOXF2: view

Pathways for RHOXF2 Gene

SuperPathways for RHOXF2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RHOXF2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with RHOXF2: view

No data available for Pathways by source for RHOXF2 Gene

Transcripts for RHOXF2 Gene

mRNA/cDNA for RHOXF2 Gene

(24) Selected AceView cDNA sequences:
(5) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RHOXF2 Gene

Rhox homeobox family, member 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RHOXF2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RHOXF2 Gene

No ASD Table

Relevant External Links for RHOXF2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RHOXF2 Gene

mRNA expression in normal human tissues for RHOXF2 Gene

mRNA differential expression in normal tissues according to GTEx for RHOXF2 Gene

This gene is overexpressed in Testis (46.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RHOXF2 Gene

SOURCE GeneReport for Unigene cluster for RHOXF2 Gene Hs.567620

mRNA Expression by UniProt/SwissProt for RHOXF2 Gene

Tissue specificity: Testis. Not detected in epididymis nor placenta.
genes like me logo Genes that share expressions with RHOXF2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and Expression partners for RHOXF2 Gene

Orthologs for RHOXF2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RHOXF2 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia -- 36
  • 22 (a)
-- 36
  • 22 (a)
(Pan troglodytes)
Mammalia -- 36
  • 82 (a)
-- 36
  • 93 (a)
Species with no ortholog for RHOXF2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RHOXF2 Gene

Gene Tree for RHOXF2 (if available)
Gene Tree for RHOXF2 (if available)

Paralogs for RHOXF2 Gene

Paralogs for RHOXF2 Gene

Selected SIMAP similar genes for RHOXF2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RHOXF2: view

Variants for RHOXF2 Gene

Sequence variations from dbSNP and Humsavar for RHOXF2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs27736 -- 120,161,042(-) CAGGC(A/G)CTTGA intron-variant
rs445473 -- 120,158,078(+) AAAAA(A/G)AAAGA upstream-variant-2KB
rs6646595 -- 120,156,727(+) gatga(C/G)aaaac upstream-variant-2KB
rs6646597 -- 120,158,462(+) caccc(A/T)actac upstream-variant-2KB
rs6646598 -- 120,158,569(+) CCACA(A/G)CAAAT utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for RHOXF2 Gene

Variant ID Type Subtype PubMed ID
dgv2469e1 CNV Complex 17122850
nsv7457 OTHER Inversion 18451855
nsv526653 CNV Gain 19592680
nsv9970 CNV Gain 18304495
nsv9971 CNV Gain 18304495

Relevant External Links for RHOXF2 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RHOXF2 Gene

Disorders for RHOXF2 Gene

No disorders were found for RHOXF2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RHOXF2 Gene

Publications for RHOXF2 Gene

  1. Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis. (PMID: 12490318) Wayne C.M. … Wilkinson M.F. (Gene 2002) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3

Products for RHOXF2 Gene

Sources for RHOXF2 Gene

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