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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RHOJ Gene

protein-coding   GIFtS: 56
GCID: GC14P063671

Ras Homolog Family Member J

(Previous names: RAS-like, family 7, member B, ras homolog gene family, member...)
(Previous symbols: RASL7B, ARHJ)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ras Homolog Family Member J1 2     Ras-Like Protein Family Member 7B2 3
ARHJ1 2 3 5     Tc10-Like GTP-Binding Protein2 3
RASL7B1 2 3     TC10B2
TCL2 3 5     Rho-Related GTP-Binding Protein RhoJ2
Ras Homolog Gene Family, Member J1 2     TC10-Like Rho GTPase2
RAS-Like, Family 7, Member B1 2     RHOI3

External Ids:    HGNC: 6881   Entrez Gene: 573812   Ensembl: ENSG000001267857   OMIM: 6076535   UniProtKB: Q9H4E53   

Export aliases for RHOJ gene to outside databases

Previous GC identifers: GC14P061662 GC14P062740 GC14P043837


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RHOJ Gene:
This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal
adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular
endothelial growth factor and may regulate angiogenesis. (provided by RefSeq, Dec 2011)

GeneCards Summary for RHOJ Gene: 
RHOJ (ras homolog family member J) is a protein-coding gene. Diseases associated with RHOJ include carpal tunnel syndrome, and endotheliitis, and among its related super-pathways are Signaling by Rho GTPases and Signaling by GPCR. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RHOH.

UniProtKB/Swiss-Prot: RHOJ_HUMAN, Q9H4E5
Function: GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in
fibroblasts and is involved in the regulation of cell morphology (By similarity)

Gene Wiki entry for RHOJ Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RHOJ gene promoter:
         POU6F1 (c2)   PPAR-gamma1   POU2F1   POU2F1b   POU2F1a   STAT3   PPAR-gamma2   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRHOJ promoter sequence
   Search SABiosciences Chromatin IP Primers for RHOJ

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHOJ


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q23.2   Ensembl cytogenetic band:  14q23.2   HGNC cytogenetic band: 14q23.1

RHOJ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RHOJ gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P063671:  view genomic region     (about GC identifiers)

Start:
63,670,832 bp from pter      End:
63,759,937 bp from pter
Size:
89,106 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RHOJ_HUMAN, Q9H4E5 (See protein sequence)
Recommended Name: Rho-related GTP-binding protein RhoJ precursor  
Size: 214 amino acids; 23821 Da
Subunit: Interacts with the CRIB domains of proteins such as Pak1 and Was/Wasp (By similarity)
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Sequence caution: Sequence=BAB55013.1; Type=Frameshift; Positions=143;
Secondary accessions: Q96KC1
Alternative splicing: 2 isoforms:  Q9H4E5-1   Q9H4E5-2   (No experimental confirmation available. Could be created by usage of an unusual splicing donor site)

Explore the universe of human proteins at neXtProt for RHOJ: NX_Q9H4E5

Explore proteomics data for RHOJ at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H4E5

  • RHOJ Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RHOJ Protein Expression
    REFSEQ proteins: NP_065714.1  
    ENSEMBL proteins: 
     ENSP00000451796   ENSP00000316729   ENSP00000451643  
    Reactome Protein details: Q9H4E5
    Human Recombinant Protein Products for RHOJ: 
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    Novus Biologicals RHOJ Protein
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    Cloud-Clone Corp. Proteins for RHOJ 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005622intracellular ----
    GO:0005829cytosol TAS--
    GO:0005886plasma membrane TAS--
    GO:0016020membrane ----

    RHOJ for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR003578 Small_GTPase_Rho
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q9H4E5

    ProtoNet protein and cluster: Q9H4E5

    2 Blocks protein domains:
    IPB001806 Transforming protein P21 RAS signature
    IPB003578 Ras small GTPase


    UniProtKB/Swiss-Prot: RHOJ_HUMAN, Q9H4E5
    Similarity: Belongs to the small GTPase superfamily. Rho family


    RHOJ for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RHOJ_HUMAN, Q9H4E5
    Function: GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in
    fibroblasts and is involved in the regulation of cell morphology (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity NAS10967094
    GO:0005515protein binding ----
    GO:0005525GTP binding IEA--
         
    RHOJ for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RHOJ:
     Increased peripheral focal adh 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rhoj):
     cardiovascular system  vision/eye 

    RHOJ for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RHOJ 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RHOJ

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RHOJ 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RHOJ 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RHOJ
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate RHOJ:
    hsa-miR-182 hsa-miR-9 hsa-miR-4257
    SwitchGear 3'UTR luciferase reporter plasmidRHOJ 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHOJ


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RHOJ About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Rho GTPase cycle
    Rho GTPase cycle1.00
    Signaling by Rho GTPases1.00
    2Signaling by GPCR
    Signal Transduction0.55
    3Insulin Signaling
    Insulin Signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for RHOJ
        Insulin Signaling


    3        Reactome Pathways for RHOJ
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    RHOJ for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RHOJ

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/15 Interacting proteins for RHOJ (Q9H4E53 ENSP000003167294) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACVR1Q047713, ENSP000002636404I2D: score=3 STRING: ENSP00000263640
    PAK1Q131533, ENSP000002785684I2D: score=3 STRING: ENSP00000278568
    SMAD2Q157963, ENSP000002621604I2D: score=3 STRING: ENSP00000262160
    WASP427683, ENSP000003658914I2D: score=2 STRING: ENSP00000365891
    CDC42P609533, ENSP000003144584I2D: score=1 STRING: ENSP00000314458
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process NAS10967094
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0007266Rho protein signal transduction IEA--
    GO:0008360regulation of cell shape IEA--

    RHOJ for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RHOJ

    1 HMDB Compound for RHOJ    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about RHOJ

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RHOJ gene: 
    NM_020663.4  

    Unigene Cluster for RHOJ:

    Ras homolog family member J
    Hs.656339  [show with all ESTs]
    Unigene Representative Sequence: NM_020663
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000557447 ENST00000316754(uc001xgb.2) ENST00000557133 ENST00000555125

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate RHOJ:
    hsa-miR-182 hsa-miR-9 hsa-miR-4257
    SwitchGear 3'UTR luciferase reporter plasmidRHOJ 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RHOJ
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RHOJ

    Additional mRNA sequence: 

    AB209218.1 AF087862.1 AF309563.1 AF498977.1 AJ276567.1 AK027278.1 AK027351.1 AK096948.1 
    BC025770.1 BC062575.1 

    10 DOTS entries:

    DT.97839937  DT.95369845  DT.120772794  DT.97839936  DT.97833617  DT.91731831  DT.120772761  DT.100740244 
    DT.444282  DT.95369843 

    24/107 AceView cDNA sequences (see all 107):

    BX953040 AI066690 N27528 AI583530 BM685133 BU663360 BM932130 AK096948 
    AW022318 AF309563 AA249338 AI081149 AA424648 BM708726 BC062575 AA020825 
    AJ276567 AI379302 BX504485 AI167357 BI764851 AA723041 BM512249 NM_020663 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RHOJ expression in normal human tissues (normalized intensities)      RHOJ embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTGCCACG
    RHOJ Expression
    About this image


    RHOJ expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/21 selected tissues (see all 21) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 19 entries
             PureStem endothelial progenitor 30-SM2-1
             Endothelial-like cells ( Derivation and purification of endothelial precursor cells...
             Human Cardiac Microvascular Endothelial Cells (HCMEC)   
             cd31+ cells   
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 4 entries
             Wharton's jelly-derived stem cells
             Human Umbilical Vein Endothelial Cells (HUVEC) (BioTime)   
     
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             PureStem endothelial progenitor 30-MV2-12
             cd31+ cells   
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 3 entries
             PureStem 4D20.8, NCr-fac Progenitor
             mesenchyme   
     
     Dermis (Hematopoietic System)    fully expand to see all 3 entries
             Human Dermal Microvascular Endothelial Cells (HDMEC)   

    See RHOJ Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RHOJ

    SOURCE GeneReport for Unigene cluster: Hs.656339
        SABiosciences Custom PCR Arrays for RHOJ
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RHOJ gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rhoj1 , 5 ras homolog gene family, member J1, 5 87.85(n)1
    92.99(a)1
      12 (32.63 cM)5
    808371  NM_023275.21  NP_075764.11 
     753083225 
    chicken
    (Gallus gallus)
    Aves RHOJ1 ras homolog gene family, member J 81.93(n)
    88.32(a)
      423513  XM_421413.3  XP_421413.1 
    lizard
    (Anolis carolinensis)
    Reptilia RHOJ6
    ras homolog family member J
    86(a)
    1 ↔ 1
    1(2355840-2449913)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.133162 Transcribed sequence with moderate similarity to protein more 80.57(n)    BX727320.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rhoj1 ras homolog gene family, member J 74.66(n)
    87.24(a)
      556371  NM_001044801.2  NP_001038266.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CDC426
    Small rho-like GTPase, essential for establishment...
    58(a)
    1 → many
    XII(604212-604787)


    ENSEMBL Gene Tree for RHOJ (if available)
    TreeFam Gene Tree for RHOJ (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RHOJ gene
    RHOH2  RHOQ2  RHOBTB12  RHOV2  RHOU2  RHOG2  RHOBTB22  RAC12  
    RAC22  CDC422  RAC32  
    18/41 SIMAP similar genes for RHOJ using alignment to 3 protein entries:     RHOJ_HUMAN (see all proteins) (see all similar genes):
    RHOQ    CDC42    RAC2    RAC1    RHOF    RAC3
    ARHG    RHOG    RHOH    RHOC    RHOU    RHOD
    RHOB    RHOA    ARHH    RHOV    ARHE    RND3

    RHOJ for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1766 SNPs in RHOJ are shown (see all 1766)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs727125451,2
    C--63669147(+) CCACAT/GTCACT 1 -- us2k14Minor allele frequency- G:0.13NA WA EA 360
    rs1862808651,2
    --63669185(+) AAGAAA/CCTTCT 1 -- us2k10--------
    rs1432450931,2
    --63669203(+) CTGCCA/TAATAC 1 -- us2k10--------
    rs1447259381,2
    --63669211(+) TACATA/GTCATC 1 -- us2k10--------
    rs171008441,2
    C,F,H--63669262(+) GGATGA/TAGTCT 1 -- us2k127Minor allele frequency- T:0.14NA NS EA CSA WA 2913
    rs795849411,2
    F--63669316(+) TGCCAC/ACTTCA 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs19577811,2
    C,F,H--63669426(-) GATTTA/GTATAA 1 -- us2k112Minor allele frequency- G:0.13NS EA NA WA 1166
    rs19577801,2
    C,F,O,H--63669442(-) ACCTAC/TGACTT 1 -- us2k122Minor allele frequency- T:0.05NS EA NA WA CSA 1712
    rs1180197891,2
    F--63669468(+) AGAATG/AGCACT 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs558062651,2
    C,F--63669587(+) GGTAGG/AATTAT 1 -- us2k12Minor allele frequency- A:0.08NA 122

    HapMap Linkage Disequilibrium report for RHOJ (63670832 - 63759937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for RHOJ (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv398e199CNV Deletion23128226
    esv2658318CNV Deletion23128226
    esv2748771CNV Deletion23290073
    nsv902017CNV Loss21882294
    nsv516899CNV Loss19592680
    nsv826963CNV Loss20364138
    esv28040CNV Loss19812545
    nsv521404CNV Loss19592680
    dgv87e55CNV Gain17911159
    dgv137n21CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607653    OMIM disorders: --

    3 diseases for RHOJ:    About MalaCards
    carpal tunnel syndrome    endotheliitis    melanoma


    RHOJ for disorders           About GeneDecksing

    Genetic Association Database (GAD): RHOJ
    Human Genome Epidemiology (HuGE) Navigator: RHOJ (1 document)

    Export disorders for RHOJ gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RHOJ gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with RHOJ)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of TCL, a new GTPase of the Rho family related to TC10 and Cdc42. (PubMed id 10967094)1, 2, 3, 9 Vignal E.... Fort P. (2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. RhoJ modulates melanoma invasion by altering actin cyt oskeletal dynamics. (PubMed id 23253891)1 Ho H....Ganesan A.K. (2013)
    6. Arhgef15 promotes retinal angiogenesis by mediating VE GF-induced Cdc42 activation and potentiating RhoJ inactivation in endothelial ce lls. (PubMed id 23029280)1 Kusuhara S....Uemura A. (2012)
    7. RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage. (PubMed id 22971344)1 Ho H....Ganesan A.K. (2012)
    8. The role of RhoJ in endothelial cell biology and angi ogenesis. (PubMed id 22103495)1 Leszczynska K....Heath V.L. (2011)
    9. RhoJ/TCL regulates endothelial motility and tube form ation and modulates actomyosin contractility and focal adhesion numbers. (PubMed id 21148427)1 Kaur S....Heath V.L. (2011)
    10. RhoJ is an endothelial cell-restricted Rho GTPase tha t mediates vascular morphogenesis and is regulated by the transcription factor ERG. (PubMed id 21628409)1 Yuan L....Oettgen P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57381 HGNC: 688 AceView: RHOJ Ensembl:ENSG00000126785 euGenes: HUgn57381
    ECgene: RHOJ H-InvDB: RHOJ

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RHOJ Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RHOJ Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RHOJ gene:
    Search GeneIP for patents involving RHOJ

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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