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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RHOD Gene

protein-coding GIFtS: 55
GCID: GC11P066824

ras homolog family member D

(Previous names: ras homolog gene family, member D )
(Previous symbol: ARHD)

Explore 63 diseases affiliated with
RHOD via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ras Homolog Family Member D¹ ²		RHOHP1² ⁵
ARHD¹ ² ³ ⁵		RhoD¹
Rho¹ ²		RHOM²
Ras Homolog Gene Family, Member D¹ ²		Ras Homolog D²
RhoHP1¹ ³		Ras Homolog Gene Family, Member A²
Rho-Related Protein HP1² ³		Rho-Related GTP-Binding Protein RhoD²

External Ids:	HGNC: 670¹	Entrez Gene: 29984²	Ensembl: ENSG00000173156⁷	OMIM: 605781⁵	UniProtKB: O00212³

Export aliases for RHOD gene to outside databases

Previous GC identifers: GC11P066600 GC11P066580 GC11P063152

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RHOD:

Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a

critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small

GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may

coordinate membrane transport with the function of the cytoskeleton. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RHOD_HUMAN, O00212

Function: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton.

Participates in reorganization of actin cytoskeleton (By similarity)

Gene Wiki entry for RHOD (RhoD)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_167190.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RHOD gene promoter:
Tal-1 Pax-5 RelA NF-kappaB Tal-1beta E47 PPAR-alpha AREB6 NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RHOD promoter sequence

Search SABiosciences Chromatin IP Primers for RHOD

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHOD

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q14.3 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q14.3

RHOD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RHOD gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P066824: view genomic region (about GC identifiers)

Start:	66,824,289 bp from pter	End:	66,839,488 bp from pter
Size:	15,200 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHOD_HUMAN, O00212 (See protein sequence)

Recommended Name: Rho-related GTP-binding protein RhoD precursor

Size: 210 amino acids; 23413 Da

Subunit: In the GTP-bound form, interacts with DIAPH2 isoform 3. Interacts with PAK7/PAK5

Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)

1 PDB 3D structure from and Proteopedia for RHOD:

2J1L (3D)

Explore the universe of human proteins at neXtProt for RHOD: NX_O00212

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O00212

RHOD Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055393.1

ENSEMBL proteins:

ENSP00000308576 ENSP00000431167 ENSP00000432003

Reactome Protein details: O00212
Human Recombinant Protein Products for RHOD:

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	ProSpec Recombinant Protein for RHOD
	Uscn Proteins for RHOD

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005829	cytosol	TAS	--
GO:0005886	plasma membrane	TAS	--
GO:0016020	membrane	--	--

RHOD for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for RHOD

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RHOD for domains About GeneDecksing

3 InterPro domains/families:

IPR003578 Small_GTPase_Rho

IPR005225 Small_GTP-bd_dom

IPR001806 Small_GTPase

Graphical View of Domain Structure for InterPro Entry O00212

ProtoNet protein and cluster: O00212

2 Blocks protein families:

IPB001806 Transforming protein P21 RAS signature

IPB003578 Ras small GTPase

UniProtKB/Swiss-Prot: RHOD_HUMAN, O00212

Similarity: Belongs to the small GTPase superfamily. Rho family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: RHOD_HUMAN, O00212

Function: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton.

Participates in reorganization of actin cytoskeleton (By similarity)

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003924	GTPase activity	TAS	9116026
GO:0005525	GTP binding	IEA	--

RHOD for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RHOD

miRNA Products:		OriGene 3'-UTR Clone: RHOD Browse MicroRNA Expression Plasmids
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHOD (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHOD OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHOD

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Cell death signalling via NRAGE, NRIF and NADE

Rho GTPase cycle

0.25

Signaling by Rho GTPases

0.25

Axon guidance

Axon guidance

1.00

Signaling by GPCR

Signal Transduction

0.56

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Reactome Pathways for RHOD

	Signaling by Rho GTPases
	Signal Transduction
	Rho GTPase cycle

1 Kegg Pathway (Kegg details for RHOD):

Axon guidance

RHOD for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RHOD

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/87 Interacting proteins for RHOD (O00212³ ENSP00000308576⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 87)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SMAD2	Q15796³, ENSP00000262160⁴	I2D: score=4 STRING: ENSP00000262160
ACVR1	Q04771³, ENSP00000263640⁴	I2D: score=3 STRING: ENSP00000263640
DIAPH2	O60879³, ENSP00000321348⁴	I2D: score=3 STRING: ENSP00000321348
HRAS	P01112³, ENSP00000309845⁴	I2D: score=3 STRING: ENSP00000309845
PLXNA1	Q9UIW2³, ENSP00000251772⁴	I2D: score=2 STRING: ENSP00000251772

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006184	GTP catabolic process	TAS	9116026
GO:0007264	small GTPase mediated signal transduction	TAS	--
GO:0007266	Rho protein signal transduction	TAS	9116026
GO:0051056	regulation of small GTPase mediated signal transduction	TAS	--

RHOD for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

RHOD for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RHOD

1 HMDB Compound for RHOD About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

10/81 Novoseek chemical compound relationships for RHOD gene (see all 81) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
gdp	82.2	90	9287351 (4), 18377644 (2), 9681826 (2), 8810315 (2) (see all 54)
geranylgeranyl pyrophosphate	80.9	13	11864926 (2), 11470741 (1), 15389884 (1), 15853754 (1) (see all 9)
gtp	80.4	108	18377644 (6), 11606631 (3), 9681826 (2), 8810315 (2) (see all 73)
mdi-a	72.3	7	18829452 (2), 14765113 (2), 12857739 (1), 11509578 (1) (see all 5)
y27632	68.8	3	16690038 (1), 16476521 (1), 19038009 (1)
mevalonate	66.6	7	18817639 (1), 18427282 (1), 15389884 (1), 15853754 (1) (see all 6)
guanosine	65.5	21	14752271 (1), 16242565 (1), 17024099 (1), 10092231 (1) (see all 21)
actomyosin	64.7	12	12876554 (2), 16690038 (1), 12747959 (1), 20142793 (1) (see all 9)
farnesyl diphosphate	64	8	11470741 (1), 15379639 (1), 15389884 (1), 15853754 (1) (see all 7)
tyrosine	62	74	11799111 (6), 10912996 (3), 9182707 (2), 10333476 (2) (see all 53)

Search CenterWatch for drugs/clinical trials and news about RHOD

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RHOD gene:

NM_014578.3

Unigene Cluster for RHOD:

Ras homolog family member D

Hs.15114 [show with all ESTs]

Unigene Representative Sequence: NM_014578

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000308831(uc001ojv.3) ENST00000533360 ENST00000532559

miRNA Products:		OriGene 3'-UTR Clone: RHOD Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RHOD
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RHOD (see all 7) OriGene shRNA RFP: RHOD OriGene siRNA: RHOD
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		Sirion Biotech Custom design and validation of potent shRNA sequences against RHOD

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHOD (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHOD OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RHOD (NM_014578)
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RHOD

Additional cDNA sequence:

AF498973.1 BC001338.1

4 DOTS entries:

DT.313169 DT.100745305 DT.97840931 DT.95087569

24/91 AceView cDNA sequences (see all 91):

NM_014578 BM761353 CR621680 AA074341 BM699832 CA446579 BC001338 CN479735

CA433897 BM981905 CR611537 AI928332 AI420794 BM845106 CR619606 BF438987

AI080694 BF436046 AI095916 BE857629 AA056032 BX284004 BM842527 BQ447278

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for RHOD About this scheme

ExUns:	1	^	2	^	3	^	4	^	5
SP1:
SP2:			-		-

ECgene alternative splicing isoforms for RHOD

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RHOD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACAACGTCCA

About this image

RHOD expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RHOD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RHOD

SOURCE GeneReport for Unigene cluster: Hs.15114

UniProtKB/Swiss-Prot: RHOD_HUMAN, O00212

Tissue specificity: Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other

tissues

SABiosciences Custom PCR Arrays for RHOD

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHOD

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for RHOD gene from 2/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC776504¹	rho-related GTP-binding protein RhoF-like	66.5(n) 57.95(a)		776504 XM_001236021.2 XP_001236022.2
zebrafish (Danio rerio)	Actinopterygii	CABZ01060030.1⁶	--	1(a)	possible ortholog	8(52269695-52274823)

ENSEMBL Gene Tree for RHOD (if available)
TreeFam Gene Tree for RHOD (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RHOD gene

RHOB² RND1² RHOA² RHOF² RHOC² RND3²

18/71 SIMAP similar genes for RHOD using alignment to 3 protein entries: RHOD_HUMAN (see all proteins) (see all similar genes):

RHOB RHOC RHOA CDC42 RAC3 RND2

RAC2 RAC1 RHOJ ARHG RHOG RHOV

RND3 ARHE RHOQ ARHA RHOH RHOU

RHOD for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs116612647^1,2		--	66822365(+)	`GTCTAC/TCTCGT`	1	--	us2k¹		1		WA	118
rs80073487^1,2	C,F	--	66822372(+)	`TCGTGG/TTCTGA`	1	--	us2k¹		1		WA	118
rs17148051^1,2	C,F,H	--	66822639(+)	`ACTGTA/GTAGCA`	1	--	us2k¹		12		NA NS EA	1068
rs148155990^1,2		--	66822642(+)	`GTATAA/GCATGA`	1	--	us2k¹		0	--	--	--	--
rs187958607^1,2		--	66822667(+)	`GTCATA/TACAGA`	1	--	us2k¹		0	--	--	--	--
rs191130990^1,2		--	66822671(+)	`TTACAC/GAGATT`	1	--	us2k¹		0	--	--	--	--
rs78524282^1,2	C	--	66822685(+)	`CCTATA/GGCAAC`	1	--	us2k¹		2		CSA WA	120
rs182103231^1,2		--	66822743(+)	`CTGGCA/CCCACC`	1	--	us2k¹		0	--	--	--	--
rs947941^1,2	C,F,H	--	66822779(-)	`CTGTCA/GTCAGG`	1	--	us2k¹		23		MN NS EA NA WA CSA	1915
rs61891303^1,2		--	66822904(+)	`ACTGCC/TGAGCC`	1	--	us2k¹		1		NA	2

HapMap Linkage Disequilibrium report for RHOD (66824289 - 66839488 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RHOD: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RHOD

DNA2.0 Custom Variant and Variant Library Synthesis for RHOD

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RHOD for disorders           About GeneDecksing

OMIM gene information: 605781    OMIM disorders: --

20/63 diseases for RHOD (see all 63):    About MalaCards

wiskott-aldrich syndrome non-small cell lung carcinoma developmental disabilities clostridium difficile

clear cell renal cell carcinoma myotonic dystrophy neutrophil immunodeficiency syndrome tuberous sclerosis

renal cell carcinoma cerebral infarction megakaryoblastic leukemia vascular disease

hypercholesterolemia fibrosarcoma familial breast cancer carcinoma

cholera glaucoma thrombosis multiple myeloma

10/61 Novoseek disease relationships for RHOD gene (see all 61) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
wiskott-aldrich syndrome	62.6	5	8625410 (1), 12680752 (1), 18212360 (1), 11580754 (1)
colitis pseudomembranous	37.3	2	11119561 (1), 8890188 (1)
metastasis	36.2	23	12445208 (2), 9042860 (1), 14716844 (1), 16900393 (1) (see all 21)
cancer	24.8	37	14999150 (3), 19355891 (3), 16234258 (2), 15739201 (2) (see all 27)
tumors	24.5	60	15588766 (3), 19166232 (3), 15013523 (2), 10328216 (2) (see all 43)
carcinosarcoma 256 walker	24.3	1	15950966 (1)
atherosclerosis	21	4	15706042 (1), 16640963 (1), 18222728 (1), 18561944 (1)
radiation enteritis	20.5	2	15710979 (2)
myotonic dystrophy	17.8	3	15894391 (1), 10542285 (1)
astrocytoma	16.8	2	11462805 (2)

Export disorders for RHOD gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for RHOD gene, integrated from 9 sources (see all 820):
(articles sorted by number of sources associating them with RHOD)

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Isolation of a novel human cDNA (rhoHP1) homologous to rho genes. (PubMed id 9116026)^{1, 2, 3} Shimizu F.... Nakamura Y. (1997)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
RhoD regulates endosome dynamics through diaphanous-related formin and Src tyrosine kinase. (PubMed id 12577064)^{1, 2} Gasman S.... Zerial M. (2003)
A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. (PubMed id 17029007)^{1, 9} Ito Y....Tada A. (2007)
Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways. (PubMed id 14749388)^{1, 9} Jaffe A.B.... Hall A. (2004)
Stabilization of anaphase midzone microtubules is reg ulated by Rho during cytokinesis in human fibrosarcoma cells. (PubMed id 19576212)^{1, 9} Kanada M....Uyeda T.Q. (2009)
Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain. (PubMed id 17916560)^{1, 9} Tong Y....Buck M. (2007)
Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch. (PubMed id 16651639)^{1, 9} Birukova A.A....Birukov K.G. (2006)
Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse. (PubMed id 11784792)^{1, 9} Zanata S.M....Puschel A.W. (2002)
A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease. (PubMed id 18407999)^{1, 9} Yanagisawa M....Anastasiadis P.Z. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29984	HGNC: 670	AceView: RHOD	Ensembl:ENSG00000173156	euGenes: HUgn29984
ECgene: RHOD	Kegg: 29984	H-InvDB: RHOD

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for RHOD	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RHOD gene
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Patent Information for RHOD gene:
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ras homolog family member D

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