Aliases for RHOBTB3 Gene
Aliases for RHOBTB3 Gene
External Ids for RHOBTB3 Gene
- HGNC: 18757
- Entrez Gene: 22836
- Ensembl: ENSG00000164292
- OMIM: 607353
- UniProtKB: O94955
Previous GeneCards Identifiers for RHOBTB3 Gene
- GC05P094324
- GC05P095531
- GC05P095082
- GC05P095141
- GC05P095092
- GC05P090257
Summaries for RHOBTB3 Gene
-
RHOBTB3 is a member of the evolutionarily conserved RHOBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351).[supplied by OMIM, Apr 2004]
GeneCards Summary for RHOBTB3 Gene
RHOBTB3 (Rho Related BTB Domain Containing 3) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and Retrograde transport at the Trans-Golgi-Network. GO annotations related to this gene include GTP binding and Rab GTPase binding.
UniProtKB/Swiss-Prot for RHOBTB3 Gene
-
Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RHOBTB3 Gene
Genomics for RHOBTB3 Gene
Regulatory Elements for RHOBTB3 Gene
Enhancers for RHOBTB3 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RHOBTB3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for RHOBTB3 Gene
- Chromosome:
- 5
- Start:
- 95,713,522 bp from pter
- End:
- 95,824,383 bp from pter
- Size:
- 110,862 bases
- Orientation:
- Plus strand
Genomic View for RHOBTB3 Gene
Genes around RHOBTB3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q15 by Ensembl
- 5q15 by Entrez Gene
- 5q15 by HGNC
RHOBTB3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RHOBTB3 Gene
Proteins for RHOBTB3 Gene
-
Protein details for RHOBTB3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O94955-RHBT3_HUMAN
- Recommended name:
- Rho-related BTB domain-containing protein 3
- Protein Accession:
- O94955
- A0PJA4
- A8K1W9
- Q8IW06
Protein attributes for RHOBTB3 Gene
- Size:
- 611 amino acids
- Molecular mass:
- 69413 Da
- Quaternary structure:
-
- Interacts with RAB9A and RAB9B (at lower level compared to RAB9A-binding). Interacts with M6PRBP1/TIP47.
- SequenceCaution:
-
- Sequence=BAA74901.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for RHOBTB3 Gene
Post-translational modifications for RHOBTB3 Gene
Other Protein References for RHOBTB3 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for RHOBTB3
- Novus Biologicals Antibodies for RHOBTB3
-
Abcam antibodies for RHOBTB3
- Invitrogen Antibodies for RHOBTB3
- antibodies-online Antibodies for RHOBTB3: See all 19
- GeneTex RHOBTB3 antibody for RHOBTB3
Protein Products
-
OriGene Purified Proteins for RHOBTB3
- Search Origene for MassSpec and Protein Over-expression Lysates for RHOBTB3
- Origene Custom Protein Services for RHOBTB3
- antibodies-online Proteins for RHOBTB3: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for RHOBTB3
-
Abcam proteins for RHOBTB3
No data available for DME Specific Peptides for RHOBTB3 Gene
Domains & Families for RHOBTB3 Gene
Gene Families for RHOBTB3 Gene
Protein Domains for RHOBTB3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RHOBTB3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O94955UniProtKB/Swiss-Prot:
RHBT3_HUMAN :- Although predicted to be a GTP-binding protein because of the presence of a Rho-like region, binds and hydrolyzes ATP. In contrast to Rho-like proteins, the conserved Asp residue in position 138 in the G4 region is replaced by an Asn, decreasing the ability to bind GTP.
- Domain:
-
- Although predicted to be a GTP-binding protein because of the presence of a Rho-like region, binds and hydrolyzes ATP. In contrast to Rho-like proteins, the conserved Asp residue in position 138 in the G4 region is replaced by an Asn, decreasing the ability to bind GTP.
Function for RHOBTB3 Gene
Molecular function for RHOBTB3 Gene
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=48 uM for ATP {ECO:0000269 PubMed:19490898};
- UniProtKB/Swiss-Prot Function:
- Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9.
Enzyme Numbers (IUBMB) for RHOBTB3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 19490898 |
| GO:0005524 | ATP binding | IDA,IEA | 19490898 |
| GO:0005525 | GTP binding | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for RHOBTB3 Gene
- MGI mutant phenotypes for RHOBTB3:
-
inferred from 1 alleles
- mortality/aging
- behavior/neurological phenotype
- growth/size/body region phenotype
- immune system phenotype
- cardiovascular system phenotype
- digestive/alimentary phenotype
- reproductive system phenotype
- endocrine/exocrine gland phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- hematopoietic system phenotype
- renal/urinary system phenotype
- craniofacial phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for RHOBTB3:
Animal Models for RHOBTB3 Gene
- MGI Knock Outs for RHOBTB3:
-
- Rhobtb3 tm1a(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RHOBTB3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for RHOBTB3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RHOBTB3 gene
- Search ViGene Biosciences for RHOBTB3
CRISPR Products
-
OriGene CRISPR knockouts for RHOBTB3
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHOBTB3
- GenScript: Design CRISPR guide RNA sequences for RHOBTB3
miRNA for RHOBTB3 Gene
- miRTarBase miRNAs that target RHOBTB3
-
- hsa-mir-215-5p (MIRT024323)
- hsa-mir-192-5p (MIRT026931)
- hsa-mir-98-5p (MIRT027831)
- hsa-mir-432-5p (MIRT439770)
- hsa-mir-377-3p (MIRT469219)
- hsa-mir-6802-5p (MIRT469220)
- hsa-mir-4536-5p (MIRT469221)
- hsa-mir-6832-5p (MIRT469222)
- hsa-mir-4451 (MIRT469223)
- hsa-mir-379-5p (MIRT469224)
- hsa-mir-3529-5p (MIRT469225)
- hsa-mir-4650-3p (MIRT469226)
- hsa-mir-7153-5p (MIRT469227)
- hsa-mir-146b-5p (MIRT469228)
- hsa-mir-146a-5p (MIRT469229)
- hsa-mir-342-3p (MIRT469230)
- hsa-mir-6865-5p (MIRT469231)
- hsa-mir-6815-5p (MIRT469232)
- hsa-mir-3123 (MIRT469233)
- hsa-mir-3925-5p (MIRT469234)
- hsa-mir-6768-5p (MIRT469235)
- hsa-mir-664b-5p (MIRT527969)
- hsa-mir-381-3p (MIRT527970)
- hsa-mir-300 (MIRT527971)
- hsa-mir-624-3p (MIRT527972)
- hsa-mir-1303 (MIRT666562)
- hsa-mir-3149 (MIRT666563)
- hsa-mir-3187-3p (MIRT666564)
- hsa-mir-4435 (MIRT666565)
- hsa-mir-588 (MIRT666566)
- hsa-mir-4701-5p (MIRT666567)
- hsa-mir-548s (MIRT666568)
- hsa-mir-653-3p (MIRT666569)
- hsa-mir-4420 (MIRT666570)
- hsa-mir-181b-3p (MIRT666571)
- hsa-mir-181b-2-3p (MIRT666572)
- hsa-mir-411-5p (MIRT666573)
- hsa-mir-4775 (MIRT666574)
- hsa-mir-19b-2-5p (MIRT666575)
- hsa-mir-19b-1-5p (MIRT666576)
- hsa-mir-19a-5p (MIRT666577)
- hsa-mir-2052 (MIRT666578)
- hsa-mir-193b-5p (MIRT666579)
- hsa-mir-4735-5p (MIRT666580)
- hsa-mir-1208 (MIRT666581)
- hsa-mir-6760-3p (MIRT666582)
- hsa-mir-483-5p (MIRT666583)
- hsa-mir-892c-3p (MIRT666584)
- hsa-mir-4676-3p (MIRT666585)
- hsa-mir-452-5p (MIRT666586)
- hsa-mir-590-3p (MIRT666587)
- hsa-mir-7154-5p (MIRT700189)
- hsa-mir-5007-3p (MIRT700190)
- hsa-mir-4664-5p (MIRT700191)
- hsa-mir-342-5p (MIRT700192)
- hsa-mir-4999-5p (MIRT700193)
- hsa-mir-4718 (MIRT700194)
- hsa-mir-1537-5p (MIRT700195)
- hsa-mir-6847-3p (MIRT700196)
- hsa-mir-8060 (MIRT700197)
- hsa-mir-135a-3p (MIRT700198)
- hsa-mir-6782-5p (MIRT700199)
- hsa-mir-4760-3p (MIRT700200)
miRNA Products
- Search ViGene Biosciences for RHOBTB3
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for RHOBTB3
- Browse OriGene Inhibitory RNA Products For RHOBTB3
-
ViGene Biosciences ready-to-package AAV shRNAs for RHOBTB3 gene
Clone Products
-
OriGene ORF clones in human for RHOBTB3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RHOBTB3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RHOBTB3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RHOBTB3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for RHOBTB3
-
ViGene Biosciences adenoviral particle packaged cDNA for RHOBTB3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RHOBTB3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RHOBTB3 gene
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RHOBTB3 Gene
Localization for RHOBTB3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RHOBTB3 Gene
- Golgi apparatus.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| golgi apparatus | 5 |
| cytosol | 3 |
| endosome | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0005829 | cytosol | IEA | -- |
| GO:0032588 | trans-Golgi network membrane | TAS | -- |
Pathways & Interactions for RHOBTB3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Vesicle-mediated transport | ||
| 2 | Golgi-to-ER retrograde transport | ||
| 3 | Retrograde transport at the Trans-Golgi-Network | ||
Pathways by source for RHOBTB3 Gene
4 Reactome pathways for RHOBTB3 Gene
Interacting Proteins for RHOBTB3 Gene
Selected Interacting proteins:
ENSP00000369318
O94955-RHBT3_HUMAN
for RHOBTB3 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0007264 | small GTPase mediated signal transduction | IEA | -- |
| GO:0008584 | male gonad development | IEA | -- |
| GO:0016192 | vesicle-mediated transport | IEA | -- |
| GO:0042147 | retrograde transport, endosome to Golgi | IMP | 19490898 |
No data available for SIGNOR curated interactions for RHOBTB3 Gene
Transcripts for RHOBTB3 Gene
mRNA/cDNA for RHOBTB3 Gene
- (4) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (453) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RHOBTB3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for RHOBTB3
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHOBTB3
- GenScript: Design CRISPR guide RNA sequences for RHOBTB3
miRNA Products
- Search ViGene Biosciences for RHOBTB3
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for RHOBTB3
- Browse OriGene Inhibitory RNA Products For RHOBTB3
-
ViGene Biosciences ready-to-package AAV shRNAs for RHOBTB3 gene
Clone Products
-
OriGene ORF clones in human for RHOBTB3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RHOBTB3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RHOBTB3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RHOBTB3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | · | 13c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for RHOBTB3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- NULL (Uncategorized)
-
Ovary (Reproductive System)
- Cumulus Cells Antral Follicle
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
- Neural Tube (Nervous System)
- Limb (Muscoskeletal System)
- Adipose (Muscoskeletal System)
- Endoderm (Gastrulation Derivatives)
- Heart (Cardiovascular System)
- Primitive Streak (Early Embryonic Tissues)
-
Placenta (Extraembryonic Tissues)
-
Pancreas (Endocrine System)
This gene is overexpressed in Placenta (41.8) and Bone (13.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RHOBTB3 Gene
NURSA nuclear receptor signaling pathways regulating expression of RHOBTB3 Gene:
RHOBTB3SOURCE GeneReport for Unigene cluster for RHOBTB3 Gene:
Hs.445030mRNA Expression by UniProt/SwissProt for RHOBTB3 Gene:
O94955-RHBT3_HUMAN
Tissue specificity:
Ubiquitous. Highly expressed in neural and cardiac tissues, pancreas, placenta and testis.
Evidence on tissue expression from TISSUES for RHOBTB3 Gene
- Nervous system(4.7)
- Muscle(4.3)
- Skin(3.6)
- Pancreas(2.1)
- Lung(2)
Primer Products
-
OriGene qPCR primer pairs for RHOBTB3
-
OriGene qPCR primer pairs and template standards for RHOBTB3
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RHOBTB3 Gene
Orthologs for RHOBTB3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RHOBTB3 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | RHOBTB3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | RHOBTB3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Rhobtb3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Rhobtb3 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | RHOBTB3 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | RHOBTB3 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RHOBTB3 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | RHOBTB3 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rhobtb3 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | si:dkey-6b12.5 34 |
|
||
| RHOBTB3 35 |
|
OneToOne |
- Species where no ortholog for RHOBTB3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for RHOBTB3 Gene
(1) SIMAP similar genes for RHOBTB3 Gene using alignment to 10 proteins:
No data available for Paralogs for RHOBTB3 Gene
Variants for RHOBTB3 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000005574 | -- | 95,785,330(+) | CTTAC(A/G)CCTGG | intron-variant | |
| rs1000062755 | -- | 95,736,229(+) | ATTTT(A/T)AATTT | intron-variant | |
| rs1000107543 | -- | 95,711,652(+) | GTAAG(-/GC)GGTGG | intron-variant, upstream-variant-2KB | |
| rs1000191075 | -- | 95,767,043(+) | GCAAA(A/G)CCCTG | intron-variant | |
| rs1000206368 | -- | 95,749,324(+) | AATAT(G/T)CATTA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3605839 | CNV | loss | 21293372 |
| esv3605840 | CNV | loss | 21293372 |
| nsv598955 | CNV | gain | 21841781 |
| nsv830409 | CNV | gain | 17160897 |
| nsv964909 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
44.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.17;
80.81% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for RHOBTB3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RHOBTB3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RHOBTB3 Gene
Disorders for RHOBTB3 Gene
Relevant External Links for RHOBTB3
No disorders were found for RHOBTB3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RHOBTB3 Gene
Publications for RHOBTB3 Gene
- Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. (PMID: 19834535) Wheeler H.E. … Kim S.K. (PLoS Genet. 2009) 3 46 64
- RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport. (PMID: 19490898) Espinosa E.J. … Pfeffer S.R. (Cell 2009) 3 4 64
- Evolution of the Rho family of ras-like GTPases in eukaryotes. (PMID: 17035353) Boureux A. … Fort P. (Mol. Biol. Evol. 2007) 2 3 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
Products for RHOBTB3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for RHOBTB3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for RHOBTB3
- Search Origene for MassSpec and Protein Over-expression Lysates for RHOBTB3
- Origene Custom Protein Services for RHOBTB3
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for RHOBTB3
- Browse OriGene Inhibitory RNA Products For RHOBTB3
- OriGene qPCR primer pairs and template standards for RHOBTB3
- OriGene qPCR primer pairs for RHOBTB3
- OriGene CRISPR knockouts for RHOBTB3
- OriGene ORF clones in human for RHOBTB3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RHOBTB3
- GenScript: Next-day shipping cDNA ORF clone for RHOBTB3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for RHOBTB3
- GenScript Custom Assay Services for RHOBTB3
- GenScript Custom overexpressing Cell Line Services for RHOBTB3
- GenScript: Design CRISPR guide RNA sequences for RHOBTB3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for RHOBTB3
- Sino Biological Human cDNA Clone for RHOBTB3
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for RHOBTB3
- Novus Biologicals proteins and lysates for RHOBTB3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for RHOBTB3
- Abcam proteins for RHOBTB3
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Invitrogen Antibodies for RHOBTB3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for RHOBTB3: See all 19
- Search antibodies-online for kits
- antibodies-online Proteins for RHOBTB3: See all 6
- Search antibodies-online for peptides
- GeneTex RHOBTB3 antibody for RHOBTB3
- Search GeneTex for Proteins for RHOBTB3
- ViGene Biosciences adenoviral particle packaged cDNA for RHOBTB3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for RHOBTB3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for RHOBTB3 gene
- Search ViGene Biosciences for RHOBTB3
- Search Santa Cruz Biotechnology (SCBT) for RHOBTB3 Antibodies
- Search Santa Cruz Biotechnology (SCBT) for RHOBTB3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RHOBTB3
- Horizon Cell Lines for RHOBTB3
- Cyagen custom Knockout/knockin (KOKI) mouse models for RHOBTB3
- VectorBuilder custom plasmid, inducible vectors for RHOBTB3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RHOBTB3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RHOBTB3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer