Aliases for RHO Gene
Aliases for RHO Gene
External Ids for RHO Gene
- HGNC: 10012
- Entrez Gene: 6010
- Ensembl: ENSG00000163914
- OMIM: 180380
- UniProtKB: P08100
Previous HGNC Symbols for RHO Gene
- RP4
Previous GeneCards Identifiers for RHO Gene
- GC03P126073
- GC03P129884
- GC03P130529
- GC03P130568
- GC03P130730
- GC03P129247
- GC03P126630
- GC03P129529
- GC03P129607
- GC03P129675
Summaries for RHO Gene
-
The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness. [provided by RefSeq, Aug 2017]
GeneCards Summary for RHO Gene
RHO (Rhodopsin) is a Protein Coding gene. Diseases associated with RHO include Retinitis Pigmentosa 4 and Night Blindness, Congenital Stationary, Autosomal Dominant 1. Among its related pathways are Organelle biogenesis and maintenance and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and photoreceptor activity. An important paralog of this gene is OPN1SW.
UniProtKB/Swiss-Prot for RHO Gene
-
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
Additional gene information for RHO Gene
- Monarch Initiative
- Search for RHO at DataMed
- Search for RHO at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RHO Gene
Genomics for RHO Gene
GeneHancer (GH) Regulatory Elements for RHO Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH03I129530 | Enhancer | 0.7 | Ensembl ENCODE | 550.8 | +1.8 | 1762 | 0.8 | SP1 GLIS1 ZSCAN4 CTBP2 PRDM10 ZNF444 ZIC2 | RHO H1FOO | |
GH03I129528 | Promoter | 0.5 | EPDnew | 550.8 | 0.0 | -19 | 0.1 | RHO GC03M129503 | ||
GH03I129591 | Promoter/Enhancer | 2.6 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 10.4 | +72.3 | 72335 | 19.4 | HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A YBX1 FEZF1 DMAP1 | PLXND1 RPL32P3 IFT122 LINC02021 ACAD9 H1FX-AS1 RHO ENSG00000244932 ENSG00000203644 H1FOO | |
GH03I129438 | Promoter/Enhancer | 2.3 | EPDnew Ensembl ENCODE dbSUPER | 10.4 | -87.9 | -87917 | 4.5 | HDGF PKNOX1 SMAD1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 POLR2B | IFT122 MBD4 RPL32P3 PLXND1 RHO GC03P129770 PIR50923 GC03P129766 | |
GH03I129525 | Enhancer | 1.1 | FANTOM5 Ensembl ENCODE | 18.7 | -2.4 | -2438 | 2 | HDGF MAX ZIC2 ATF2 POLR2A IKZF1 ZNF24 MYC SPI1 | RPL32P3 IFT122 RHO PLXND1 MBD4 GC03M129503 |
Regulatory Element Products
Genomic Locations for RHO Gene
- chr3:129,528,639-129,535,344
- (GRCh38/hg38)
- Size:
- 6,706 bases
- Orientation:
- Plus strand
- chr3:129,247,482-129,254,187
- (GRCh37/hg19)
Genomic View for RHO Gene
- Cytogenetic band:
-
- 3q22.1 by Ensembl
- 3q22.1 by Entrez Gene
- 3q22.1 by HGNC


RefSeq DNA sequence for RHO Gene
Proteins for RHO Gene
-
Protein details for RHO Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P08100-OPSD_HUMAN
- Recommended name:
- Rhodopsin
- Protein Accession:
- P08100
- Q16414
- Q2M249
Protein attributes for RHO Gene
- Size:
- 348 amino acids
- Molecular mass:
- 38893 Da
- Quaternary structure:
-
- Homodimer.
Protein Expression for RHO Gene
Post-translational modifications for RHO Gene
- Contains one covalently linked retinal chromophore.
- Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
- Glycosylation at Asn2 and isoforms=15
Other Protein References for RHO Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for RHO (Rhodopsin)
-
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-
Abcam antibodies for RHO
-
Cloud-Clone Corp. Antibodies for RHO
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-
Santa Cruz Biotechnology (SCBT) Antibodies for RHO
Protein Products
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Cloud-Clone Corp. Proteins for RHO
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-
Abcam proteins for RHO
Assay Products
-
Cloud-Clone Corp. Assay Kits for RHO
- antibodies-online: Search results for 12 available Rhodopsin Elisa Kits ranked by validation data
- Compare Top Rhodopsin Elisa Kits
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Recommended
- 2 Chemical ELISA Kits
- 1 Chicken ELISA Kit
- 2 Cow (Bovine) ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 3 Human ELISA Kits
- 2 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 2 Rat (Rattus) ELISA Kits
- 2 Chemical ELISA Kits
- 1 Chicken ELISA Kit
- 2 Cow (Bovine) ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 3 Human ELISA Kits
- 2 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 2 Rat (Rattus) ELISA Kits
No data available for DME Specific Peptides for RHO Gene
Domains & Families for RHO Gene
Gene Families for RHO Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- G-protein coupled receptors
- Potential drug targets
- Predicted membrane proteins
- Transporters
Protein Domains for RHO Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RHO Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P08100UniProtKB/Swiss-Prot:
OPSD_HUMAN :- Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
- Family:
-
- Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Function for RHO Gene
Molecular function for RHO Gene
- GENATLAS Biochemistry:
- rhodopsin,G protein coupled receptor superfamily,visual pigment of the rod cells of retina
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Absorption: Abs(max)=495 nm;
- UniProtKB/Swiss-Prot Function:
- Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
Phenotypes From GWAS Catalog for RHO Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004871 | signal transducer activity | IEA | -- |
GO:0004930 | G-protein coupled receptor activity | TAS | 8107847 |
GO:0005502 | 11-cis retinal binding | ISS | -- |
GO:0005515 | protein binding | IPI | 12754272 |
GO:0008020 | G-protein coupled photoreceptor activity | IBA,ISS | -- |
Phenotypes for RHO Gene
- MGI mutant phenotypes for RHO:
- inferred from 19 alleles
- GenomeRNAi human phenotypes for RHO:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- shRNA abundance <= 50%
- Decreased viability in esophageal squamous lineage
- Decreased viability ratio
- Resistant to vaccinia virus (VACV-A4L) infection
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Decreased shRNA abundance (Z-score < -2)
- Increased shRNA abundance (Z-score > 2)
- Increased Sindbis virus (SINV) infection
- Increased Nanog expression
Animal Models for RHO Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for RHO gene
-
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- Search ViGene Biosciences for RHO
CRISPR Products
-
OriGene CRISPR knockouts for RHO
- genomics-online: gRNA clones - Search results for 33 available Rhodopsin gene related products
- Overview of 33 available Rhodopsin gene related products
- Applied Biological Materials CRISPR for RHO
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Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHO
- GenScript: Design CRISPR guide RNA sequences for RHO
miRNA for RHO Gene
- miRTarBase miRNAs that target RHO
miRNA Products
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Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for RHO
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- Overview of 33 available RHO gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for RHO gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RHO
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for RHO
-
ViGene Biosciences adenoviral particle packaged cDNA for RHO gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RHO gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RHO gene
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for RHO Gene
Localization for RHO Gene
Subcellular locations from UniProtKB/Swiss-Prot for RHO Gene
- Membrane; Multi-pass membrane protein. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000139 | Golgi membrane | TAS | -- |
GO:0001750 | photoreceptor outer segment | IEA,IDA | 11767049 |
GO:0001917 | photoreceptor inner segment | IEA,IDA | 11767049 |
GO:0005794 | Golgi apparatus | IDA | 11767049 |
GO:0005886 | plasma membrane | IDA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for RHO Gene
Pathways & Interactions for RHO Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Phototransduction | ||
2 | Peptide ligand-binding receptors | ||
3 | Signaling by GPCR | ||
4 | Cargo trafficking to the periciliary membrane | ||
5 | Organelle biogenesis and maintenance |
.56
|
Pathways by source for RHO Gene
1 Cell Signaling Technology pathway for RHO Gene
4 BioSystems pathways for RHO Gene
1 KEGG pathway for RHO Gene
1 GeneGo (Thomson Reuters) pathway for RHO Gene
1 Qiagen pathway for RHO Gene
Interacting Proteins for RHO Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001523 | retinoid metabolic process | TAS | -- |
GO:0006468 | protein phosphorylation | IEA | -- |
GO:0007165 | signal transduction | IEA | -- |
GO:0007186 | G-protein coupled receptor signaling pathway | TAS | -- |
GO:0007601 | visual perception | IEA | -- |
No data available for SIGNOR curated interactions for RHO Gene
Drugs & Compounds for RHO Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Halothane | Approved, Vet_approved | Pharma | Activator, Target, other | 2 | ||
Palmitic Acid | Approved, Experimental | Pharma | Full agonist, Agonist, Target | 23 | ||
Zoledronic acid | Approved | Pharma | Inhibition, Inhibitor | Potent nitrogen-containing bisphosphonates, Osteoclast function modifiers (important in bone metastasis) | 304 | |
Hexadecanal | Experimental | Pharma | Target | 0 | ||
N-Acetylmethionine | Experimental | Pharma | Target | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
trifluoroacetic acid |
|
76-05-1 |
|
(1) ApexBio Compounds for RHO Gene
Compound | Action | Cas Number |
---|---|---|
Zoledronic Acid | Potent nitrogen-containing bisphosphonates | 118072-93-8 |
Transcripts for RHO Gene
mRNA/cDNA for RHO Gene
- (1) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (364) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for RHO
- genomics-online: gRNA clones - Search results for 33 available Rhodopsin gene related products
- Overview of 33 available Rhodopsin gene related products
- Applied Biological Materials CRISPR for RHO
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHO
- GenScript: Design CRISPR guide RNA sequences for RHO
miRNA Products
- Search ViGene Biosciences for RHO
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for RHO
- Browse OriGene Inhibitory RNA Products For RHO
- genomics-online: shRNA clones - Search results for 33 available RHO gene related products
- Overview of 33 available RHO gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for RHO gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RHO
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RHO
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RHO
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for RHO Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Rod Precursor Cells Outer Nuclear Layer
- Mature Rod Cells Outer Nuclear Layer
- Retina
- Photoreceptor-like cells(Osakada F et. al. 2008)
- Photoreceptor-like cells(Osakada F et. al. 2009)
- NULL (Sensory Organs)
-
Neurons
- Rod Precursor Cells Outer Nuclear Layer
- Mature Rod Cells Outer Nuclear Layer
mRNA differential expression in normal tissues according to GTEx for RHO Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RHO Gene
NURSA nuclear receptor signaling pathways regulating expression of RHO Gene:
RHOSOURCE GeneReport for Unigene cluster for RHO Gene:
Hs.247565mRNA Expression by UniProt/SwissProt for RHO Gene:
P08100-OPSD_HUMANEvidence on tissue expression from TISSUES for RHO Gene
- Eye(5)
- Muscle(3.2)
- Nervous system(2.5)
Phenotype-based relationships between genes and organs from Gene ORGANizer for RHO Gene
- ectoderm
- endoderm
- mesoderm
- cardiovascular
- immune
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- brain
- cerebellum
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- middle ear
- nose
- outer ear
- skull
- penis
- testicle
- blood
- blood vessel
- peripheral nervous system
- red blood cell
- skin
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for RHO
-
OriGene qPCR primer pairs and template standards for RHO
- genomics-online: primer clones - Search results for 33 available RHO gene related products
- Overview of 33 available RHO gene related products
Orthologs for RHO Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | RHO 33 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | RHO 34 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | RHO 33 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | RHO 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | RHO 33 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Rho 33 |
|
||
mouse (Mus musculus) |
Mammalia | Rho 33 16 34 |
|
||
chicken (Gallus gallus) |
Aves | RHO 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | RHO 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | rho 33 |
|
||
Str.5791 33 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | rho-prov 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | RHO (4 of 4) 34 |
|
OneToMany | |
rho 33 34 |
|
||||
exorh 33 |
|
||||
rhol 34 |
|
OneToMany | |||
opn1sw2 34 |
|
OneToMany | |||
rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.11367 33 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.11297 34 |
|
ManyToMany | |
-- 34 |
|
ManyToMany |
- Species where no ortholog for RHO was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for RHO Gene
Variants for RHO Gene
SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs104893768 | pathogenic, Retinitis pigmentosa 4, not provided, Retinitis pigmentosa 4 (RP4) [MIM:613731] | 129,528,801(+) | C/A | coding_sequence_variant, missense_variant | |
rs104893769 | pathogenic, Retinitis pigmentosa 4, Retinitis pigmentosa 4 (RP4) [MIM:613731] | 129,528,783(+) | C/T | coding_sequence_variant, missense_variant | |
rs104893770 | pathogenic, Retinitis pigmentosa 4, Retinitis pigmentosa 4 (RP4) [MIM:613731] | 129,528,866(+) | T/C | coding_sequence_variant, missense_variant | |
rs104893771 | pathogenic, Retinitis pigmentosa 4, Retinitis pigmentosa 4 (RP4) [MIM:613731] | 129,528,993(+) | T/A | coding_sequence_variant, missense_variant | |
rs104893772 | pathogenic, Retinitis pigmentosa 4, Retinitis pigmentosa 4 (RP4) [MIM:613731] | 129,528,999(+) | G/A | coding_sequence_variant, missense_variant |
Additional Variant Information for RHO Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RHO Gene
Disorders for RHO Gene

(46) MalaCards diseases for RHO Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
retinitis pigmentosa 4 |
|
|
night blindness, congenital stationary, autosomal dominant 1 |
|
|
fundus albipunctatus |
|
|
rhyns syndrome |
|
|
retinitis pigmentosa |
|
UniProtKB/Swiss-Prot
OPSD_HUMAN- Night blindness, congenital stationary, autosomal dominant 1 (CSNBAD1) [MIM:610445]: A non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia. {ECO:0000269 PubMed:7846071, ECO:0000269 PubMed:8358437, ECO:0000269 PubMed:9888392}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Retinitis pigmentosa 4 (RP4) [MIM:613731]: A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. {ECO:0000269 PubMed:1302614, ECO:0000269 PubMed:1391967, ECO:0000269 PubMed:1833777, ECO:0000269 PubMed:1840561, ECO:0000269 PubMed:1862076, ECO:0000269 PubMed:1897520, ECO:0000269 PubMed:1985460, ECO:0000269 PubMed:19934218, ECO:0000269 PubMed:19960070, ECO:0000269 PubMed:2137202, ECO:0000269 PubMed:2215617, ECO:0000269 PubMed:22334370, ECO:0000269 PubMed:2239971, ECO:0000269 PubMed:7633434, ECO:0000269 PubMed:7981701, ECO:0000269 PubMed:7987326, ECO:0000269 PubMed:7987331, ECO:0000269 PubMed:8045708, ECO:0000269 PubMed:8076945, ECO:0000269 PubMed:8081400, ECO:0000269 PubMed:8088850, ECO:0000269 PubMed:8317502, ECO:0000269 PubMed:8353500, ECO:0000269 PubMed:8554077, ECO:0000269 PubMed:9452035}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for RHO
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Tumor Gene Database
- (TGDB)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for RHO Gene
Publications for RHO Gene
- [Digenic association of RHO and RP1 genes with retinitis pigmentosa among Chinese population in Hong Kong]. (PMID: 16185528) Wang DY … Pang CP (Zhonghua yi xue za zhi 2005) 3 22 44 58
- Retinitis punctata albescens associated with the Arg135Trp mutation in the rhodopsin gene. (PMID: 8554077) Souied E … Kaplan J (American journal of ophthalmology 1996) 3 4 44 58
- Rhodopsin mutation proline347-to-alanine in a family with autosomal dominant retinitis pigmentosa indicates an important role for proline at position 347. (PMID: 7633434) Macke JP … Nathans J (Human molecular genetics 1995) 3 4 22 58
- Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip. (PMID: 20801516) Booij JC … Florijn RJ (Ophthalmology 2011) 3 44 58
- Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa. (PMID: 20591486) Clark GR … Simpson DA (Ophthalmology 2010) 3 44 58
Products for RHO Gene
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- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for RHO
- Cell Signaling Technology (CST) Antibodies for RHO (Rhodopsin)
- Search for Antibodies & Assays
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for RHO
- Novus Biologicals proteins and lysates for RHO
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for RHO
- Abcam proteins for RHO
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Cloud-Clone Corp. Antibodies for RHO
- Cloud-Clone Corp. Proteins for RHO
- Cloud-Clone Corp. Assay Kits for RHO
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for RHO
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for RHO
- Cyagen custom Knockout/knockin (KOKI) mouse models for RHO
- VectorBuilder custom plasmid, inducible vectors for RHO
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RHO
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 28 available Rhodopsin Antibodies ranked by validation data
- Compare Top Rhodopsin Antibodies
- antibodies-online: Search results for 12 available Rhodopsin Elisa Kits ranked by validation data
- Compare Top Rhodopsin Elisa Kits
- Recommended
- 2 Chemical ELISA Kits
- 1 Chicken ELISA Kit
- 2 Cow (Bovine) ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 3 Human ELISA Kits
- 2 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 2 Rat (Rattus) ELISA Kits
- 2 Chemical ELISA Kits
- 1 Chicken ELISA Kit
- 2 Cow (Bovine) ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 3 Human ELISA Kits
- 2 Mouse (Murine) ELISA Kits
- 1 Pig (Porcine) ELISA Kit
- 2 Rat (Rattus) ELISA Kits
- antibodies-online: Search results for 6 available Rhodopsin Proteins ranked by validation data
- Compare Top Rhodopsin Proteins
- GeneTex RHO antibody for RHO
- Search GeneTex for Proteins for RHO
- ViGene Biosciences adenoviral particle packaged cDNA for RHO gene
- ViGene Biosciences lentiviral particle packaged cDNA for RHO gene
- ViGene Biosciences ready-to-package AAV shRNAs for RHO gene
- Search ViGene Biosciences for RHO
- Santa Cruz Biotechnology (SCBT) Antibodies for RHO
- Search Santa Cruz Biotechnology (SCBT) for RHO siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RHO
- Horizon Cell Lines for RHO
- genomics-online: cdna clones - Search results for 33 available Rhodopsin gene related products
- Overview of 33 available Rhodopsin gene related products
- orf clones - Search results for 33 available Rhodopsin gene related products
- Overview of 33 available Rhodopsin gene related products
- genomics-online: gRNA clones - Search results for 33 available Rhodopsin gene related products
- Overview of 33 available Rhodopsin gene related products
- genomics-online: primer clones - Search results for 33 available Rhodopsin gene related products
- Overview of 33 available Rhodopsin gene related products
- genomics-online: shRNA clones - Search results for 33 available Rhodopsin gene related products
- Overview of 33 available Rhodopsin gene related products
Sources for RHO Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew