RHD Gene
protein-coding GIFtS: 56
GCID: GC01P025599
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|
Rh blood group, D antigen(Previous names: Rhesus blood group, D antigen )
(Previous symbol: RH)
| |
Aliases
for RHD gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rh Blood Group, D Antigen1 2 | | RHCED2 | | CD240D1 2 | | RHDVA(TT)2 | | DIIIc1 2 | | RHDel2 | | RH1 2 | | RHPII2 | | Rh41 2 | | RhDCw2 | | RhII1 2 | | RhK562-II2 | | RhPI1 2 | | Blood Group Rh(D) Polypeptide2 | | Rh Polypeptide 22 3 | | D Antigen (DCS)2 | | Rhesus D Antigen2 3 | | Rh Blood Group Antigen Evans2 | | RHXIII2 3 | | Rhesus Blood Group D Antigen Allele DIII Type 72 | | Rh30a1 | | Rhesus System D Polypeptide2 | | Rhesus Blood Group, D Antigen1 | | RhPII3 | | RH302 | | CD240D Antigen3 |
Export aliases for RHD gene to outside databasesPrevious GC identifers: GC01M025154 GC01M024859 GC01M024598 GC01P025154 GC01P025344 GC01P025471 GC01P023853 |
Summaries
for RHD gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RHD:
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is alsothe most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations.The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC andRhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of thehighly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding differentisoforms have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RHD_HUMAN, Q02161Function: May be part of an oligomeric complex which is likely to have a transport or channel function in theerythrocyte membrane
Gene Wiki entry for RHD
|
Genomic Views
for RHD gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RHD gene promoter:
SRF SRF (504 AA) Chx10 MyoD STAT3 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for RHD
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHD |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.11 Ensembl cytogenetic band: 1p36.11 HGNC cytogenetic band: 1p36.11RHD Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P025599: view genomic region
(about GC identifiers)
Start:
|
25,598,884 bp from pter |
End:
|
25,656,936 bp from pter |
Size:
|
58,053 bases |
Orientation:
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plus strand |
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Proteins
for RHD gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RHD_HUMAN, Q02161 (See
protein sequence)Recommended Name: Blood group Rh(D) polypeptide Size: 417 amino acids; 45211 Da
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: Q02162 Q07618 Q16147 Q16235 Q16355 Q5VSK0 Q9NPK0 Q9UQ20 Q9UQ21 Q9UQ22 Q9UQ23Alternative splicing: 3 isoforms: Q02161-1 Q02161-2 Q02161-3 Explore the universe of human proteins at neXtProt for RHD: NX_Q02161
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q02161
RHD Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001121163.1 NP_057208.2
ENSEMBL proteins: ENSP00000331871 ENSP00000413849 ENSP00000396420 ENSP00000350150 ENSP00000456966 ENSP00000339577 ENSP00000399640
Human Recombinant Protein Products for RHD:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RHD for ontologies About GeneDecksing
RHD Antibody Products:
Assay Products for RHD: |
Protein
Domains /
Families
for RHD gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RHD for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q02161ProtoNet protein and cluster: Q02161 2 Blocks protein families: IPB002229 Rhesus blood group protein signature IPB010256 Rh-like protein/ammonium transporter
UniProtKB/Swiss-Prot: RHD_HUMAN, Q02161Similarity: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily |
Function
for RHD gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RHD_HUMAN, Q02161Function: May be part of an oligomeric complex which is likely to have a transport or channel function in theerythrocyte membrane Genatlas biochemistry entry for RHD:Rhesus blood group,locus D,absent in the Caucasian RHD-negative phenotype
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008519 | ammonium transmembrane transporter activity |
IEA | -- |
RHD for ontologies About GeneDecksing
Phenotypes:
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Rhd):
RHD for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Rhdtm1Goo for RHD
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHD (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHD (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RHD (NM_016124) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RHD | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RHD |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHD |
|
Pathways & Interactions
for RHD gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RHD
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for RHD (Q021613 ENSP000003318714) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for RHD gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RHD for compounds About GeneDecksing
 Browse Tocris compounds for RHD
10/37 Novoseek chemical compound relationships for RHD gene (see all 37) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| methylammonium |
72.3 |
1 |
16584906 (1) |
| amtb |
58.9 |
2 |
16281947 (1), 16584906 (1) |
| ammonium |
42.7 |
10 |
16564193 (2), 11358367 (1), 19807729 (1), 16574457 (1) (see all 8) |
| phenylhydrazine |
39.8 |
2 |
2169881 (1), 7663379 (1) |
| polyacrylamide |
30.3 |
5 |
8140503 (1), 10901146 (1), 11076426 (1), 9234582 (1) (see all 5) |
| dids |
29 |
1 |
10077484 (1) |
| phospholipid |
20.3 |
6 |
9506954 (1), 1858342 (1), 8663431 (1), 9088993 (1) (see all 6) |
| diamide |
18.3 |
1 |
2168217 (1) |
| nh4cl |
13.7 |
2 |
17712059 (2) |
| glyceraldehyde 3-phosphate |
11.9 |
1 |
18721457 (1) |
1 PharmGKB related drug/compound annotation for RHD gene About this tableSearch CenterWatch for drugs/clinical trials and news about RHD
|
Transcripts
for RHD gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RHD gene (3 alternative transcripts): NM_001127691.1 NM_016124.3 NM_016225.3 Unigene Cluster for RHD: Rh blood group, D antigen Hs.449968 [show with all ESTs]Unigene Representative Sequence: NM_0161249 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000564398(uc010oep.2) ENST00000328664(uc001bjz.3 uc001bkc.3 uc009vrm.3 uc001bka.3 uc001bkb.3 uc009vrn.3 uc009vro.3 uc009vrp.3)
ENST00000454452 ENST00000423253 ENST00000417538 ENST00000357542 ENST00000568195
ENST00000342055 ENST00000423810
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHD (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHD (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RHD (NM_016124) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RHD | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RHD |
Additional cDNA sequence: AB018966.1 AB018967.1 AB018968.1 AB018969.1 AB037270.1 AB046420.1 AB049754.1 AF177938.1 AF187846.1 AF312679.1 AF510069.1 AF510070.1 AJ704215.2 AK297151.1 AM183924.3 AY449381.1 AY449382.1 AY449383.1 AY449384.1 AY449385.1 AY751491.1 AY751492.1 AY751493.1 AY751494.1 AY751495.1 AY751496.1 BC139922.1 DQ266353.1 DQ451878.1 EU557240.1 EU557241.1 EU661905.1 EU661906.1 EU661907.1 FN555129.1 FR745438.1 FR745439.1 FR745440.1 FR745441.1 HE657775.1 JF436967.1 JF436968.1 JN635688.1 JN635689.1 JQ065733.1 JQ424879.1 L08429.1 S57971.1 S70174.1 S73913.1 S78509.1 S82449.1 X63094.1 X63097.1 Z97026.1 11 DOTS entries: DT.456144 DT.100706780 DT.121396511 DT.121396578 DT.121396677 DT.40295556 DT.75124277 DT.121396509 DT.95159897 DT.95260805 DT.95351321 24/60 AceView cDNA sequences (see all 60): S73913 AI282496 NM_016225 NM_016124 BU662207 AB049754 AJ704215 BV204872 S82449 AF510070 AB018968 BV204878 AY449385 AY449384 BV204875 AF510069 BU664659 BV204870 BV204861 AB018969 AY449382 BV204863 BV204880 AB018966
GeneLoc Exon Structure
|
Expression
for RHD gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RHD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RHD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RHD
SOURCE GeneReport for Unigene cluster: Hs.449968
UniProtKB/Swiss-Prot: RHD_HUMAN, Q02161Tissue specificity: Restricted to tissues or cell lines expressing erythroid characters
SABiosciences Custom PCR Arrays for RHD
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RHD
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RHD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RHD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RHD | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHD |
Orthologs
for RHD gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RHD gene from 5/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RHD1 |
Rh blood group, D antigen |
55.86(n)
42.71(a) |
|
395121 NM_204467.1 NP_989798.1 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
41(a) |
1 → many |
GL343703.1(120634-136096) |
zebrafish
(Danio rerio) |
Actinopterygii |
rhd6 |
Rh blood group, D antigen |
34(a) |
1 → many |
13(46116954-46143214) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Rh506 |
Rh50 |
26(a) |
possible ortholog |
3L(4910368-4919321) |
worm
(Caenorhabditis elegans) |
Secernentea |
rhr-16rhr-26 |
RH (Rhesus) antigen Related family member (rhr-2) |
25(a)23(a) |
many ↔ manymany ↔ many |
V(5428144-5430415) V(11727880-11730142) |
ENSEMBL Gene Tree for RHD (if available)
TreeFam Gene Tree for RHD (if available) |
Paralogs
for RHD gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RHD gene
- RHCE1 2 RHAG2 RHBG2 RHCG2
13 SIMAP similar genes for RHD using alignment to 231 protein entries: RHD_HUMAN (see all proteins):RhDCw RhC RhDTI RhD RHD/RHCE RDH
RhIVb(J) RHCE RH50 Rh50 RHAG RHBG
RHCG
RHD for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for RHD
PGOHUM00000259458
|
Genomic Variants
for RHD gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: RHD_HUMAN, Q02161Polymorphism: RHD and RHCE are responsible for the Rh blood group system. The molecular basis of the Tar=Rh40 bloodgroup antigen is a polymorphism in position 110
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RHD (25598884 - 25656936 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 21 variations for RHD
15/20 CNVs (see all 20): 34802 31614 31613 0381 23271 58379 63322 74416 2047 97322 0257 0680 34801 6821 38078
1 Inversion: 37098
Human Gene Mutation Database (HGMD): RHD
Locus Specific Mutation Databases (LSDB): RHD
Blood Group Antigen Gene Mutation Database (BGMUT) blood group system
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RHD |
|
Disorders
/ Diseases
for RHD gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RHD for disorders About GeneDecksing
OMIM gene information: 111680
OMIM disorders: --
20/54  diseases for RHD (see all 54): About MalaCardsrh-negative blood type rh isoimmunization skeletal muscle neoplasm beta thalassemia
fundus albipunctatus typhoid fever spherocytosis hydrops fetalis
elliptocytosis dyserythropoietic anemia congenital dyserythropoietic anemia jaundice
autoimmune hemolytic anemia hemolytic anemia hereditary elliptocytosis sickle cell disease
hereditary spherocytosis neonatal jaundice obstructive jaundice handedness
4 diseases from the University of Copenhagen DISEASES database for RHD:Rhabdomyosarcoma Rh isoimmunization Anemia Fundus albipunctatus 10/35 Novoseek disease relationships for RHD gene (see all 35) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| spherocytosis hereditary |
85.3 |
20 |
8140503 (2), 1295777 (1), 9844481 (1), 10766130 (1) (see all 19) |
| hemolytic disease |
75 |
8 |
7856682 (2), 19953292 (1), 11288127 (1), 14607035 (1) (see all 6) |
| elliptocytosis hereditary |
73.4 |
4 |
14695625 (1), 17414207 (1), 10037687 (1), 16985305 (1) |
| spherocytosis |
73.2 |
1 |
12719424 (1) |
| anemia dyserythropoietic congenital |
73.2 |
4 |
18166993 (1), 14533796 (1) |
| anemia hemolytic |
62.2 |
4 |
10766130 (1), 15961204 (1), 11102985 (1), 9235914 (1) |
| rh hemolytic disease |
58.3 |
7 |
16396876 (1), 15961204 (1) |
| protein deficiency |
46.7 |
3 |
12828006 (1), 14636652 (1), 15279669 (1) |
| hemolysis |
45 |
2 |
9504940 (1), 19704946 (1) |
| anemia |
30.2 |
5 |
9504940 (1), 18166993 (1), 19508687 (1), 14533796 (1) |
Genetic Association Database (GAD): RHD
Human Genome Epidemiology (HuGE) Navigator: RHD (65 documents)
Export disorders for RHD gene to outside databases
|
Publications
for RHD gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RHD gene, integrated from 9 sources (see all 334):
(articles sorted by number of sources associating them with RHD) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- RHD gene polymorphism among RhD-negative Han Chinese. (PubMed id 14570619)1, 4, 9 Xu Q....Si G. (2003)
- Prenatal RHD gene determination and dosage analysis by PCR: clinical evaluation. (PubMed id 11288127)1, 4, 9 Chan F.Y....Hyland C.A. (2001)
- Rh(D) antigen expression and isolation of a new Rh(D) cDNA isoform in human erythroleukemic K562 cells. (PubMed id 8080999)1, 2, 9 Suyama K.... Goldstein J. (1994)
- Molecular cloning and primary structure of the human blood group RhD polypeptide. (PubMed id 1438298)1, 2, 9 le van Kim C.... Colin Y. (1992)
- Random survey for RHD alleles among D+ European persons. (PubMed id 15987365)1, 4 Chen Q. and Flegel W.A. (2005)
- RhD variants in Caucasians: consequences for checking clinically relevant alleles. (PubMed id 15318849)1, 4 Ansart-Pirenne H....Noizat-Pirenne F. (2004)
- Genetic characterization of the population of Grande Comore Island (Njazidja) according to major blood groups. (PubMed id 15754970)1, 4 Chiaroni J....Boetsch G. (2004)
- [Gene frequencies and heterozygosity of the AB0 and RH blood group alleles in the populations of two cities of the Donetsk region, Ukraine] (PubMed id 12760254)1, 4 Mukhin V.N....Afanas'ev M.V. (2003)
- Fetal RHD genotyping in maternal serum during the first trimester of pregnancy. (PubMed id 12358932)1, 4 Costa J.M....Gautier E. (2002)
- RHD maternal-fetal genotype incompatibility increases schizophrenia susceptibility. (PubMed id 12439825)1, 4 Palmer C.G....Woodward J.A. (2002)
|
External Searches for RHD gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RHD gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RHD gene
(According to HUGE)
About This Section
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Specialized Databases showing RHD gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for RHD | Pharmacogenomics, SNPs, Pathways | | dbRBC/BGMUT | http://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=rh | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/RHD |
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About This Section
| Patent Information for RHD gene:
Search GeneIP for patents involving RHD
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RHD gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RHD | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RHD | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RHD | | | OriGene Protein Over-expression Lysate for RHD | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RHD | | OriGene 3'-UTR Clone for RHD | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RHD | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RHD | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RHD | | OriGene Custom Protein Services for RHD | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RHD | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RHD | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHD | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RHD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RHD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RHD |
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| | | | Search Tocris compounds for RHD |
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 | | | RHD Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHD |
|  |  |  |  | | | | ThermoFisher Antibodies for RHD |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RHD |
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