Aliases for RHD Gene
Aliases for RHD Gene
- Rh Blood Group D Antigen 2 3 5
- Rhesus D Antigen 3 4
- RHXIII 3 4
- RHPII 3 4
- Rhesus Blood Group D Antigen Allele DIII Type 7 3
- Truncated Rhesus Blood Group D Antigen 3
- Truncated Rh Blood Group D Antigen 3
- Rhesus Blood Group, D Antigen 2
- Blood Group Rh(D) Polypeptide 3
- Rh Blood Group Antigen Evans 3
- Rh Blood Group CcEe Antigen 3
- Rhesus System D Polypeptide 3
- Rh Blood Group CE Antigen 3
- Rh Blood Group, D Anitgen 3
- Rh Blood Group C Antigen 3
- RhD Blood Group Antigen 3
- Blood Group Protein RHD 3
- Blood Group Antigen D 3
- Truncated Rhesus D 3
- RH Polypeptide 2 3
External Ids for RHD Gene
- HGNC: 10009
- Entrez Gene: 6007
- Ensembl: ENSG00000187010
- OMIM: 111680
- UniProtKB: Q02161
Previous HGNC Symbols for RHD Gene
- RH
Previous GeneCards Identifiers for RHD Gene
- GC01M025154
- GC01M024859
- GC01M024598
- GC01P025154
- GC01P025344
- GC01P025471
- GC01P025599
- GC01P023853
Summaries for RHD Gene
-
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for RHD Gene
RHD (Rh Blood Group D Antigen) is a Protein Coding gene. Diseases associated with RHD include Rh-Null, Regulator Type and Hair Whorl. Gene Ontology (GO) annotations related to this gene include ammonium transmembrane transporter activity. An important paralog of this gene is RHCE.
UniProtKB/Swiss-Prot for RHD Gene
-
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Additional gene information for RHD Gene
- Monarch Initiative
- Search for RHD at DataMed
- Search for RHD at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RHD Gene
Genomics for RHD Gene
GeneHancer (GH) Regulatory Elements for RHD Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH01I025275 | Promoter/Enhancer | 1.1 | EPDnew dbSUPER | 550.8 | +0.1 | 97 | 0.1 | TAL1 CBFA2T3 MNT DPF2 E4F1 ZNF592 TCF12 NCOR1 HDAC2 SMARCA4 | RHD LOC105376882 RSRP1 | |
GH01I025271 | Enhancer | 0.6 | dbSUPER | 563.8 | -0.4 | -442 | 0.8 | TAL1 CBFA2T3 MNT DPF2 E4F1 ZNF592 TCF12 NCOR1 ZNF184 HDAC2 | RHD ENSG00000261349 LOC105376882 RSRP1 | |
GH01I025272 | Enhancer | 0.4 | dbSUPER | 550.8 | -0.9 | -888 | 0.1 | MGA ZNF592 | RHD ENSG00000261349 LOC105376882 RSRP1 | |
GH01I025277 | Enhancer | 0.3 | dbSUPER | 563.6 | +0.5 | 510 | 0.3 | MLLT1 | RHD LOC105376882 RSRP1 | |
GH01I025279 | Enhancer | 0.3 | dbSUPER | 550.8 | +0.7 | 708 | 0.1 | MLLT1 | LOC105376882 RHD RSRP1 |
Regulatory Element Products
Genomic Locations for RHD Gene
- chr1:25,272,393-25,330,445
- (GRCh38/hg38)
- Size:
- 58,053 bases
- Orientation:
- Plus strand
- chr1:25,598,884-25,656,936
- (GRCh37/hg19)
Genomic View for RHD Gene
- Cytogenetic band:
-
- 1p36.11 by Ensembl
- 1p36.11 by Entrez Gene
- 1p36.11 by HGNC


RefSeq DNA sequence for RHD Gene
Proteins for RHD Gene
-
Protein details for RHD Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q02161-RHD_HUMAN
- Recommended name:
- Blood group Rh(D) polypeptide
- Protein Accession:
- Q02161
- Q02162
- Q07618
- Q16147
- Q16235
- Q16355
- Q5VSK0
- Q5XLS9
- Q5XLT1
- Q5XLT2
- Q9NPK0
- Q9UQ20
- Q9UQ21
- Q9UQ22
- Q9UQ23
Protein attributes for RHD Gene
- Size:
- 417 amino acids
- Molecular mass:
- 45211 Da
- Quaternary structure:
- No Data Available
Protein Expression for RHD Gene
Post-translational modifications for RHD Gene
Other Protein References for RHD Gene
Antibody Products
- Novus Biologicals Antibodies for RHD
-
Abcam antibodies for RHD
-
Cloud-Clone Corp. Antibodies for RHD
- Invitrogen Antibodies for RHD
- Search GeneTex for Antibodies for RHD
-
Santa Cruz Biotechnology (SCBT) Antibodies for RHD
Protein Products
-
OriGene Purified Proteins for RHD
- Search Origene for MassSpec and Protein Over-expression Lysates for RHD
- Origene Custom Protein Services for RHD
- Novus Biologicals lysates for RHD
-
Cloud-Clone Corp. Proteins for RHD
- antibodies-online: Search results for available RHD related products ranked by validation data
- Search GeneTex for Proteins for RHD
-
Abcam proteins for RHD
Assay Products
- antibodies-online: Search results for 6 available RHD Elisa Kits ranked by validation data
- Compare Top RHD Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for RHD Gene
Domains & Families for RHD Gene
Gene Families for RHD Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Blood group antigen proteins
- CD markers
- Predicted membrane proteins
- Transporters
Protein Domains for RHD Gene
Suggested Antigen Peptide Sequences for RHD Gene
Graphical View of Domain Structure for InterPro Entry
Q02161UniProtKB/Swiss-Prot:
RHD_HUMAN :- Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
- Family:
-
- Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Function for RHD Gene
Molecular function for RHD Gene
- GENATLAS Biochemistry:
- Rhesus blood group,locus D,absent in the Caucasian RHD-negative phenotype
- UniProtKB/Swiss-Prot Function:
- May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Phenotypes From GWAS Catalog for RHD Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008519 | ammonium transmembrane transporter activity | IBA,IEA | -- |
Phenotypes for RHD Gene
- MGI mutant phenotypes for RHD:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for RHD:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RHD
-
-
ViGene Biosciences lentiviral particle packaged cDNA for RHD gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RHD gene
- Search ViGene Biosciences for RHD
CRISPR Products
-
OriGene CRISPR knockouts for RHD
- genomics-online: gRNA clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
- Applied Biological Materials CRISPR for RHD
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHD
- GenScript: Design CRISPR guide RNA sequences for RHD
miRNA for RHD Gene
- miRTarBase miRNAs that target RHD
-
- hsa-mir-4433a-3p (MIRT453382)
- hsa-mir-4768-3p (MIRT453383)
- hsa-mir-4459 (MIRT453384)
- hsa-mir-3614-5p (MIRT453385)
- hsa-mir-6500-3p (MIRT453386)
- hsa-mir-383-5p (MIRT453387)
- hsa-mir-6516-5p (MIRT453388)
- hsa-mir-455-3p (MIRT453389)
- hsa-mir-6807-5p (MIRT453390)
- hsa-mir-4451 (MIRT453391)
- hsa-mir-6086 (MIRT453392)
- hsa-mir-6499-3p (MIRT453393)
- hsa-mir-377-5p (MIRT453394)
- hsa-mir-98-5p (MIRT453395)
- hsa-mir-4458 (MIRT453396)
- hsa-mir-4500 (MIRT453397)
- hsa-let-7i-5p (MIRT453398)
- hsa-let-7g-5p (MIRT453399)
- hsa-let-7f-5p (MIRT453400)
- hsa-let-7e-5p (MIRT453401)
- hsa-let-7d-5p (MIRT453402)
- hsa-let-7c-5p (MIRT453403)
- hsa-let-7b-5p (MIRT453404)
- hsa-mir-6840-3p (MIRT453405)
- hsa-let-7a-5p (MIRT453406)
- hsa-mir-6831-5p (MIRT453407)
- hsa-mir-665 (MIRT453408)
- hsa-mir-3927-3p (MIRT453409)
- hsa-mir-4662b (MIRT453410)
- hsa-mir-4426 (MIRT453411)
- hsa-mir-4647 (MIRT453412)
- hsa-mir-371a-5p (MIRT767178)
- hsa-mir-371b-5p (MIRT767216)
- hsa-mir-372-5p (MIRT767261)
- hsa-mir-373-5p (MIRT767307)
- hsa-mir-616-5p (MIRT776018)
- hsa-mir-6830-5p (MIRT780004)
miRNA Products
- Search ViGene Biosciences for RHD
Inhibitory RNA Products
- Origene shrna and RNAi products in human, mouse, rat for RHD
- Browse OriGene Inhibitory RNA Products For RHD
- genomics-online: shRNA clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
-
ViGene Biosciences ready-to-package AAV shRNAs for RHD gene
Clone Products
-
OriGene ORF clones in human for RHD
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RHD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RHD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RHD
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
- orf clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
- Applied Biological Materials Clones for RHD
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for RHD
-
ViGene Biosciences adenoviral particle packaged cDNA for RHD gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RHD gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RHD gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RHD Gene
Localization for RHD Gene
Subcellular locations from UniProtKB/Swiss-Prot for RHD Gene
- Membrane; Multi-pass membrane protein.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005887 | integral component of plasma membrane | TAS | 1438298 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for RHD Gene
Pathways & Interactions for RHD Gene
Interacting Proteins for RHD Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006810 | transport | IEA | -- |
GO:0015695 | organic cation transport | IBA | -- |
GO:0015696 | ammonium transport | IEA | -- |
GO:0072488 | ammonium transmembrane transport | IBA,IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for RHD Gene
Transcripts for RHD Gene
mRNA/cDNA for RHD Gene
- (10) REFSEQ mRNAs :
- (56) Additional mRNA sequences :
- (60) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RHD Gene
CRISPR Products
-
OriGene CRISPR knockouts for RHD
- genomics-online: gRNA clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
- Applied Biological Materials CRISPR for RHD
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RHD
- GenScript: Design CRISPR guide RNA sequences for RHD
miRNA Products
- Search ViGene Biosciences for RHD
Inhibitory RNA Products
- Origene shrna and RNAi products in human, mouse, rat for RHD
- Browse OriGene Inhibitory RNA Products For RHD
- genomics-online: shRNA clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
-
ViGene Biosciences ready-to-package AAV shRNAs for RHD gene
Clone Products
-
OriGene ORF clones in human for RHD
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RHD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RHD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RHD
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
- orf clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
- Applied Biological Materials Clones for RHD
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for RHD Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Erythroblasts Hematopoietic Bone Marrow
- bone marrow mononuclear cells
- Bone Marrow CD105+ Cells
- umbilical cord reticulocytes
- reticulocytes
- Bone (Muscoskeletal System)
- Umbilical Cord (Extraembryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for RHD Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RHD Gene
NURSA nuclear receptor signaling pathways regulating expression of RHD Gene:
RHDSOURCE GeneReport for Unigene cluster for RHD Gene:
Hs.449968mRNA Expression by UniProt/SwissProt for RHD Gene:
Q02161-RHD_HUMANEvidence on tissue expression from TISSUES for RHD Gene
- Bone marrow(4.4)
- Blood(3)
- Nervous system(2.6)
Phenotype-based relationships between genes and organs from Gene ORGANizer for RHD Gene
- ectoderm
- endoderm
- mesoderm
- cardiovascular
- digestive
- integumentary
- nervous
- skeletal muscle
- ear
- eye
- head
- mouth
- liver
- blood
- red blood cell
- skin
Primer Products
-
OriGene qPCR primer pairs and template standards for RHD
-
OriGene qPCR primer pairs for RHD
- genomics-online: primer clones - Search results for 134 available RHD gene related products
- Overview of 134 available RHD gene related products
-
Recommended
Orthologs for RHD Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | LOC456645 33 |
|
||
-- 34 |
|
ManyToMany | |||
-- 34 |
|
ManyToMany | |||
-- 34 |
|
ManyToMany | |||
dog (Canis familiaris) |
Mammalia | RHCE 33 |
|
||
RH30 34 |
|
OneToMany | |||
cow (Bos Taurus) |
Mammalia | LOC282685 33 |
|
||
-- 34 |
|
OneToMany | |||
mouse (Mus musculus) |
Mammalia | Rhd 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Rhd 33 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToMany | |
chicken (Gallus gallus) |
Aves | RHD 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | rhd 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | rhd 34 |
|
OneToMany | |
fruit fly (Drosophila melanogaster) |
Insecta | Rh50 34 |
|
OneToMany | |
worm (Caenorhabditis elegans) |
Secernentea | rhr-1 34 |
|
ManyToMany | |
rhr-2 34 |
|
ManyToMany | |||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.7075 34 |
|
ManyToMany | |
-- 34 |
|
ManyToMany | |||
CSA.7848 34 |
|
ManyToMany |
- Species where no ortholog for RHD was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for RHD Gene
(13) SIMAP similar genes for RHD Gene using alignment to 247 proteins:
- RHD_HUMAN
- A0FIL3_HUMAN
- A4VAS2_HUMAN
- A5PHJ8_HUMAN
- A6PZ59_HUMAN
- A6PZ60_HUMAN
- A6PZ61_HUMAN
- A7DW67_HUMAN
- A7J389_HUMAN
- A7Y8S3_HUMAN
- A8YPG4_HUMAN
- A8YPS3_HUMAN
- A8YPS4_HUMAN
- A9JPG7_HUMAN
- A9P3S3_HUMAN
- A9P3T0_HUMAN
- A9P3T1_HUMAN
- A9P3T2_HUMAN
- A9P3T3_HUMAN
- A9P3T5_HUMAN
- A9P3T6_HUMAN
- A9P3T7_HUMAN
- A9P3T8_HUMAN
- A9P3U0_HUMAN
- B0B3T3_HUMAN
- B0B3T4_HUMAN
- B0JE64_HUMAN
- B0JEG1_HUMAN
- B1PWD9_HUMAN
- B2BHH4_HUMAN
- B2L5V2_HUMAN
- B2ZGP8_HUMAN
- B2ZGP9_HUMAN
- B2ZGQ0_HUMAN
- B4F4R6_HUMAN
- B4F4R9_HUMAN
- B4F4S0_HUMAN
- B4F4S1_HUMAN
- B4F4S2_HUMAN
- B4F4S3_HUMAN
- B4F4S4_HUMAN
- B4F4S5_HUMAN
- B4F4S6_HUMAN
- B4F4S7_HUMAN
- B4F4S8_HUMAN
- B5KN93_HUMAN
- B5MEI6_HUMAN
- B5RHP0_HUMAN
- B6ETL3_HUMAN
- B6ETL4_HUMAN
- B6ETP8_HUMAN
- B6ETQ6_HUMAN
- B6ETQ7_HUMAN
- B8Q0B6_HUMAN
- B8Q0B7_HUMAN
- B8Q0B8_HUMAN
- D0AB01_HUMAN
- D0AB02_HUMAN
- D1H0P2_HUMAN
- D1H102_HUMAN
- D2CRG8_HUMAN
- D2CRH0_HUMAN
- D2CRH1_HUMAN
- D2CYW7_HUMAN
- D2CYW8_HUMAN
- D2CYW9_HUMAN
- D6Q1S7_HUMAN
- D7GNB0_HUMAN
- D7GNB2_HUMAN
- D8MJ84_HUMAN
- D8MJ86_HUMAN
- D8MJ87_HUMAN
- E1Y6M6_HUMAN
- E5BCZ9_HUMAN
- E7BAS3_HUMAN
- E7BAS4_HUMAN
- E7BAS5_HUMAN
- E7BAS6_HUMAN
- E7EVW1_HUMAN
- F2RM72_HUMAN
- G0TQY3_HUMAN
- G1AUC2_HUMAN
- G4XIC4_HUMAN
- G4XIC5_HUMAN
- G4XIC6_HUMAN
- G4XIC7_HUMAN
- G4XIC8_HUMAN
- G4XIC9_HUMAN
- G4XID0_HUMAN
- G4XID1_HUMAN
- G4XMV9_HUMAN
- G8FL61_HUMAN
- G8YY11_HUMAN
- G8YY12_HUMAN
- G8YY13_HUMAN
- G8YY14_HUMAN
- H2DQF5_HUMAN
- H2DQF6_HUMAN
- H3BT10_HUMAN
- H6SH95_HUMAN
- H8WR07_HUMAN
- H8WR09_HUMAN
- H8WR10_HUMAN
- H8WR11_HUMAN
- H8WR12_HUMAN
- I0CKF7_HUMAN
- I0CKF8_HUMAN
- I0CKG0_HUMAN
- I0CKG2_HUMAN
- I0CKG3_HUMAN
- I0CKG4_HUMAN
- I0CKG6_HUMAN
- I0CKG7_HUMAN
- I2HA00_HUMAN
- I2HA01_HUMAN
- I3W8M7_HUMAN
- I6UL51_HUMAN
- I7JB64_HUMAN
- I7JSY2_HUMAN
- I7KDN9_HUMAN
- I7L571_HUMAN
- I7LL22_HUMAN
- I7LNF1_HUMAN
- I7LP06_HUMAN
- J7GUD8_HUMAN
- J7GY11_HUMAN
- J7H0H3_HUMAN
- J7IF04_HUMAN
- J7IJ78_HUMAN
- J7ILZ7_HUMAN
- J7JLB9_HUMAN
- K4MWK1_HUMAN
- K4RNB6_HUMAN
- K4RNV5_HUMAN
- K4RNY0_HUMAN
- K4UI15_HUMAN
- K4UNQ7_HUMAN
- K4UQ06_HUMAN
- K4UQ76_HUMAN
- K8ES76_HUMAN
- K8ESS1_HUMAN
- K8FE51_HUMAN
- L0RH38_HUMAN
- L0RH60_HUMAN
- L7SYG8_HUMAN
- L8EB13_HUMAN
- M4Q981_HUMAN
- M4X2U0_HUMAN
- M5FHF1_HUMAN
- O75102_HUMAN
- O75103_HUMAN
- O75104_HUMAN
- O75835_HUMAN
- O75836_HUMAN
- O95489_HUMAN
- Q05GI4_HUMAN
- Q08GE1_HUMAN
- Q0KG01_HUMAN
- Q1KT12_HUMAN
- Q1KT13_HUMAN
- Q2A0N8_HUMAN
- Q2P9N2_HUMAN
- Q2PBC1_HUMAN
- Q2UVE8_HUMAN
- Q2UVE9_HUMAN
- Q2YHU7_HUMAN
- Q2YHU8_HUMAN
- Q2YHU9_HUMAN
- Q2YHV0_HUMAN
- Q333A6_HUMAN
- Q333X4_HUMAN
- Q49IM5_HUMAN
- Q49IM6_HUMAN
- Q4EW05_HUMAN
- Q4EW06_HUMAN
- Q4FE19_HUMAN
- Q4FE20_HUMAN
- Q59AE6_HUMAN
- Q59AE7_HUMAN
- Q5CCG6_HUMAN
- Q5CCG7_HUMAN
- Q5DVQ1_HUMAN
- Q5DVQ2_HUMAN
- Q5QPZ7_HUMAN
- Q5QPZ8_HUMAN
- Q5QPZ9_HUMAN
- Q5XLS8_HUMAN
- Q5XLT0_HUMAN
- Q5XLT3_HUMAN
- Q6A1H1_HUMAN
- Q6A1H2_HUMAN
- Q6A1H3_HUMAN
- Q6A1H4_HUMAN
- Q6KC49_HUMAN
- Q6Y8J3_HUMAN
- Q70E14_HUMAN
- Q70E15_HUMAN
- Q70E16_HUMAN
- Q70E17_HUMAN
- Q70HW2_HUMAN
- Q70P87_HUMAN
- Q70VV1_HUMAN
- Q7LGF4_HUMAN
- Q7RU08_HUMAN
- Q86SJ7_HUMAN
- Q86SN4_HUMAN
- Q86SN5_HUMAN
- Q86UI2_HUMAN
- Q86UI3_HUMAN
- Q86UI4_HUMAN
- Q8IUC5_HUMAN
- Q8NDV4_HUMAN
- Q8NDV5_HUMAN
- Q8NFY1_HUMAN
- Q8NFY2_HUMAN
- Q8WWL0_HUMAN
- Q96KN0_HUMAN
- Q96KU1_HUMAN
- Q96KU2_HUMAN
- Q96QG8_HUMAN
- Q99673_HUMAN
- Q99906_HUMAN
- Q9H248_HUMAN
- Q9H4C7_HUMAN
- Q9HCC3_HUMAN
- Q9NXY8_HUMAN
- Q9UDZ3_HUMAN
- Q9UDZ4_HUMAN
- Q9UDZ5_HUMAN
- Q9UPC8_HUMAN
- R4I4U8_HUMAN
- S5VXN0_HUMAN
- S6EY87_HUMAN
- S6FLQ0_HUMAN
- T2DJN4_HUMAN
- T2DKY0_HUMAN
- T2DL33_HUMAN
- T2DL93_HUMAN
- T2DL95_HUMAN
- T2DLL5_HUMAN
- T2LKG5_HUMAN
- T2LLM0_HUMAN
- T2LLM2_HUMAN
- T2LLP2_HUMAN
- U5U1V4_HUMAN
- U5U2J9_HUMAN
- U6Q0X6_HUMAN
Pseudogenes.org Pseudogenes for RHD Gene
Variants for RHD Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for RHD Gene
- RHD_HUMAN-Q02161
- RHD and RHCE are responsible for the Rh blood group system. The molecular basis of the Tar=Rh40 blood group antigen is a polymorphism in position 110.
SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1053355 | not-provided, Weak RhD expression | 25,301,061(+) | C/G | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
rs1053356 | not-provided, Weak RhD expression | 25,301,552(+) | T/G | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
rs1053359 | not-provided, Weak RhD expression | 25,301,582(+) | G/A/C | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
rs1053362 | not-provided, Weak RhD expression | 25,301,629(+) | C/T | coding_sequence_variant, non_coding_transcript_variant, synonymous_variant | |
rs121912762 | pathogenic, RhD category D-VII | 25,284,753(+) | T/C | 5_prime_UTR_variant, coding_sequence_variant, missense_variant, non_coding_transcript_variant |
Additional Variant Information for RHD Gene
- Human Gene Mutation Database (HGMD)
- RHD
- Blood Group Antigen Gene Mutation Database (BGMUT)
- Blood Group System
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RHD
Disorders for RHD Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
rh-null, regulator type |
|
|
hair whorl |
|
|
skeletal muscle cancer |
|
|
congenital dyserythropoietic anemia |
|
|
hereditary spherocytosis |
|
Additional Disease Information for RHD
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for RHD Gene
Publications for RHD Gene
- RHD gene polymorphism among RhD-negative Han Chinese. (PMID: 14570619) Xu Q … Si G (Chinese medical journal 2003) 3 22 44 58
- Prenatal RHD gene determination and dosage analysis by PCR: clinical evaluation. (PMID: 11288127) Chan FY … Hyland CA (Prenatal diagnosis 2001) 3 22 44 58
- Rh(D) antigen expression and isolation of a new Rh(D) cDNA isoform in human erythroleukemic K562 cells. (PMID: 8080999) Suyama K … Goldstein J (Blood 1994) 3 4 22 58
- Molecular cloning and primary structure of the human blood group RhD polypeptide. (PMID: 1438298) Le van Kim C … Colin Y (Proceedings of the National Academy of Sciences of the United States of America 1992) 3 4 22 58
- Non-invasive foetal RHD genotyping via real-time PCR of foetal DNA from Chinese RhD-negative maternal plasma. (PMID: 19545247) Wang XD … He ZM (European journal of clinical investigation 2009) 3 44 58
Products for RHD Gene
- Browse R&D Systems for Antibodies
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- Novus Biologicals Antibodies for RHD
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- Abcam antibodies for RHD
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- Find your target
- Browse Primary Antibodies
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- Cloud-Clone Corp. Antibodies for RHD
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for RHD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for RHD
- VectorBuilder custom plasmid, inducible vectors for RHD
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 44 available RHD Antibodies ranked by validation data
- Compare Top RHD Antibodies
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- Search GeneTex for Antibodies for RHD
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- ViGene Biosciences adenoviral particle packaged cDNA for RHD gene
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- Search ViGene Biosciences for RHD
- Santa Cruz Biotechnology (SCBT) Antibodies for RHD
- Search Santa Cruz Biotechnology (SCBT) for RHD siRNA/shRNA
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- genomics-online: cdna clones - Search results for 134 available RHD gene related products
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Sources for RHD Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
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- (119) Disease Ontology
- (120) Genetics Home Reference
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- (123) CDC
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- (125) NCBI Bookshelf
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- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew