Aliases for RHBDF2 Gene
External Ids for RHBDF2 Gene
Previous HGNC Symbols for RHBDF2 Gene
Previous GeneCards Identifiers for RHBDF2 Gene
GeneCards Summary for RHBDF2 Gene
RHBDF2 (Rhomboid 5 Homolog 2 (Drosophila)) is a Protein Coding gene. Diseases associated with RHBDF2 include tylosis with esophageal cancer and esophageal cancer. Among its related pathways are Signaling by GPCR and Immune System. GO annotations related to this gene include serine-type endopeptidase activity and growth factor binding. An important paralog of this gene is RHBDF1.
UniProtKB/Swiss-Prot for RHBDF2 Gene
Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity).