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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RHBDF2 Gene

protein-coding   GIFtS: 50
GCID: GC17M074466

rhomboid 5 homolog 2 (Drosophila)

(Previous names: rhomboid, veinlet-like 6 (Drosophila) )
(Previous symbol: RHBDL6)
 Explore 9 diseases affiliated with
RHBDF2 via our new
 Human Malady Compendium 
Biological research products
for RHBDF2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Rhomboid 5 Homolog 2 (Drosophila)1 2     FLJ223411
RHBDL51 2 3     Rhomboid, Veinlet-Like 6 (Drosophila)1
RHBDL61 2 3     TOC2
Rhomboid Family Member 22 3     Inactive Rhomboid Protein 22
Rhomboid Veinlet-Like Protein 52 3     IRHOM23
Rhomboid Veinlet-Like Protein 62 3     Rhomboid 5 Homolog 23
IRhom21     

External Ids:    HGNC: 207881   Entrez Gene: 796512   Ensembl: ENSG000001296677   OMIM: 6144045   UniProtKB: Q6PJF53   

Export aliases for RHBDF2 gene to outside databases

Previous GC identifers: GC17M071979 GC17M069894


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RHDF2_HUMAN, Q6PJF5
Function: Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands
of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway
and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)

Gene Wiki entry for RHBDF2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RHBDF2 gene promoter:
         Bach1   STAT1   Sp1   p300   STAT1beta   STAT1alpha   HEN1   PPAR-gamma1   PPAR-gamma2   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRHBDF2 promoter sequence
   Search SABiosciences Chromatin IP Primers for RHBDF2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHBDF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.3

RHBDF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RHBDF2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M074466:  view genomic region     (about GC identifiers)

Start:
74,466,973 bp from pter      End:
74,497,872 bp from pter
Size:
30,900 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHDF2_HUMAN, Q6PJF5 (See protein sequence)
Recommended Name: Inactive rhomboid protein 2  
Size: 856 amino acids; 96686 Da
Subunit: Interacts with EGF (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Cell membrane
Sequence caution: Sequence=AAH35829.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAB15310.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6NEM3 A8K801 Q5U607 Q5YGQ8 Q9H6E9
Alternative splicing: 2 isoforms:  Q6PJF5-1   Q6PJF5-2   

Explore the universe of human proteins at neXtProt for RHBDF2: NX_Q6PJF5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6PJF5

  • RHBDF2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001005498.2  NP_078875.4  

    ENSEMBL proteins: 
     ENSP00000322775   ENSP00000466867   ENSP00000467468   ENSP00000467549   ENSP00000465632  
     ENSP00000467677   ENSP00000464942   ENSP00000465531   ENSP00000466029   ENSP00000467971  
     ENSP00000464975   ENSP00000465990   ENSP00000465124   ENSP00000374410  

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    Uscn Proteins for RHBDF2

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane ISS--
    GO:0005886plasma membrane IDA--
    GO:0016021integral to membrane IEA--


    RHBDF2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RHBDF2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR022241 Rhomboid_SP
     IPR022764 Peptidase_S54_rhomboid_dom
     IPR002610 Peptidase_S54_rhomboid

    Graphical View of Domain Structure for InterPro Entry Q6PJF5

    ProtoNet protein and cluster: Q6PJF5

    1 Blocks protein family: IPB002610 Rhomboid-like protein

    UniProtKB/Swiss-Prot: RHDF2_HUMAN, Q6PJF5
    Similarity: Belongs to the peptidase S54 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RHDF2_HUMAN, Q6PJF5
    Function: Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands
    of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway
    and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidRHBDF2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHBDF2

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004252serine-type endopeptidase activity IEA--
    GO:0019838growth factor binding IEA--


    RHBDF2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for RHBDF2: Rhbdf2tm1.1Mfm Rhbdf2tm1Mak
         7 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Rhbdf2):
     hematopoietic system  homeostasis/metabolism  immune system  liver/biliary system  mortality/aging 
     other  skeleton 

    RHBDF2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RHBDF2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for RHBDF2 (Q6PJF53 ENSP000003227754) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EGFP011333, ENSP000002651714I2D: score=1 STRING: ENSP00000265171
    MAPK1P284823I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IEA--
    GO:0015031protein transport IEA--
    GO:0050709negative regulation of protein secretion ISS--


    RHBDF2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RHBDF2
    Search CenterWatch for drugs/clinical trials and news about RHBDF2 / RHDF2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RHBDF2 gene (2 alternative transcripts): 
    NM_001005498.3  NM_024599.5  

    Unigene Cluster for RHBDF2:

    Rhomboid 5 homolog 2 (Drosophila)
    Hs.464157  [show with all ESTs]
    Unigene Representative Sequence: NM_024599
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000590168 ENST00000313080(uc002jrq.2) ENST00000591885 ENST00000591860
    ENST00000589582 ENST00000587640 ENST00000592123 ENST00000592378 ENST00000585989
    ENST00000589526 ENST00000591697 ENST00000591879 ENST00000585701 ENST00000591192
    ENST00000590322 ENST00000590288 ENST00000591255 ENST00000593103

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    hsa-miR-186 hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidRHBDF2 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AK025994.1 AK225684.1 AK292135.1 AK292166.1 AY500247.1 BC016034.1 BC035829.1 

    9 DOTS entries:

    DT.312968  DT.102826448  DT.100023822  DT.97787408  DT.95262283  DT.91867105  DT.95262284  DT.97804853 
    DT.100805137 

    24/94 AceView cDNA sequences (see all 94):

    BM801831 AK074034 BC016034 CO245402 AI379333 BG315099 BQ941668 AI333432 
    AI365443 N47137 AI224055 BQ214211 BF338099 BG661264 NM_024599 BQ008185 
    AI539624 AI435307 BQ224539 AI433769 BQ719822 AL833680 AI382805 AW957974 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for RHBDF2 (see all 12)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a ·
    SP1:                    -     -                       -                                                                                                         
    SP2:                                                  -                 -                                                                                       
    SP3:                                                                                                                                                            
    SP4:                    -     -                       -                 -                                                                                       
    SP5:                          -                       -                 -                                                                                       

    ExUns: 15b ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21a · 21b · 21c · 21d
    SP1:                                            -                     
    SP2:                                            -                     
    SP3:                                            -                     
    SP4:                                                                  
    SP5:                                                                  


    ECgene alternative splicing isoforms for RHBDF2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RHBDF2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GATTAAATAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RHBDF2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RHBDF2

    SOURCE GeneReport for Unigene cluster: Hs.464157

    UniProtKB/Swiss-Prot: RHDF2_HUMAN, Q6PJF5
    Tissue specificity: Found in the epidermis and esophageal epithelium

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHBDF2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RHBDF2 gene from 6/26 species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves RHBDF21 rhomboid 5 homolog 2 (Drosophila) 77.93(n)
    78.84(a)
      417358  XM_415618.3  XP_415618.3 
    lizard
    (Anolis carolinensis)
    Reptilia RHBDF26
    --
    73(a)
    1 ↔ 1
    2(112147391-112171320)
    fruit fly
    (Drosophila melanogaster)
    Insecta rho-56
    rhomboid-5
    16(a)
    possible ortholog
    2L(10368025-10373900)
    worm
    (Caenorhabditis elegans)
    Secernentea rom-36
    rom-46
    RhOMboid (Drosophila) related family member (rom-3...
    RhOMboid (Drosophila) related family member (rom-4...
    24(a)
    18(a)
    possible ortholog
    possible ortholog
    IV(16965249-16970455)
    IV(16995742-17014911)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATRBL26
    ATRBL66
    (see all 10)
    RHOMBOID-like protein 6
    (see all 10)
    25(a)
    24(a)
    (see all 10)
    many ↔ many
    many ↔ many
    (see all 10)
    1(23408876-23410815)
    1(4344985-4348328)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 9)
    OsRhmbd14 - Putative Rhomboid homologue, expressed...
    OsRhmbd16 - Putative Rhomboid homologue, expressed...
    (see all 9)
    25(a)
    24(a)
    (see all 9)
    many ↔ many
    many ↔ many
    (see all 9)
    8(27373301-27376321)
    9(20549324-20552826)


    ENSEMBL Gene Tree for RHBDF2 (if available)
    TreeFam Gene Tree for RHBDF2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RHBDF2 gene
    RHBDF12  
    2 SIMAP similar genes for RHBDF2 using alignment to 11 protein entries:     RHDF2_HUMAN (see all proteins):
    FLJ00080    RHBDF1

    RHBDF2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/731 NCBI SNPs in RHBDF2 are shown (see all 731    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1826664341,2
    --74466712(+) CCCTTC/TCCTGC 2 -- int10--------
    rs770767441,2
    F,--74466790(+) CAAGTG/AGACCC 2 -- int11Minor allele frequency- A:0.06WA 118
    rs1876561731,2
    --74466836(+) GCCCAA/GCTAAT 2 -- int10--------
    rs1930288381,2
    --74466891(+) CTGCTA/GTCTCT 2 -- int10--------
    rs72168721,2
    C,H,--74466901(+) TGAGCG/AGCTGA 2 -- int117Minor allele frequency- A:0.02NS EA NA WA CSA 784
    rs1160978881,2
    F,--74466937(+) AATCCC/TAGTTT 2 -- int11Minor allele frequency- T:0.05WA 118
    rs72212251,2
    C,F,H,--74466973(+) GACAAT/GGTACT 2 -- spd110Minor allele frequency- G:0.04NS EA NA WA 1024
    rs1379104661,2
    --74467004(+) ATCCAC/TGAGAC 2 -- ut310--------
    rs81501,2
    C,F,O,A,H,--74467017(-) TTGTAC/GGGACG 2 -- ut31 ese331Minor allele frequency- G:0.46MN EA NA NS WA 6358
    rs739989111,2
    C,--74467051(+) AAGACC/TGTGAT 2 -- ut311Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for RHBDF2 (74466973 - 74497872 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RHBDF2: --
    Human Gene Mutation Database (HGMD): RHBDF2

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RHBDF2 for disorders           About GeneDecksing

    OMIM gene information: 614404    OMIM disorders: --

    UniProtKB/Swiss-Prot: RHDF2_HUMAN, Q6PJF5
  • Defects in RHBDF2 are the cause of tylosis with esophageal cancer (TOC) [MIM:148500]. An autosomal dominant
  • syndrome characterized by diffuse palmoplantar keratoderma, oral leukokeratosis, and a high lifetime risk of
    esophageal cancer

    9 diseases for RHBDF2:    About MalaCards
    nonepidermolytic palmoplantar keratoderma    keratoderma    pneumonia    tuberculosis
    malaria    tylosis with esophageal cancer    esophageal cancer    esophagitis
    mycobacterium tuberculosis

    1 disease from the University of Copenhagen DISEASES database for RHBDF2:
    Palmoplantar keratosis
    Human Genome Epidemiology (HuGE) Navigator: RHBDF2 (3 documents)

    Export disorders for RHBDF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RHBDF2 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with RHBDF2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome. (PubMed id 22265016)1, 2 Blaydon D.C.... Kelsell D.P. (2012)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
    4. Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian ca ncer. (PubMed id 22344671)1 Wojnarowicz P.M....Tonin P.N. (2012)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
    9. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79651 HGNC: 20788 AceView: RHBDL6 Ensembl:ENSG00000129667 euGenes: HUgn79651
    ECgene: RHBDF2 H-InvDB: RHBDF2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RHBDF2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RHBDF2 gene:
    Search GeneIP for patents involving RHBDF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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