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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RHBDD1 Gene

protein-coding   GIFtS: 43
GCID: GC02P227700

rhomboid domain containing 1

 Explore 1 disease affiliated with
RHBDD1 via our new
 Human Malady Compendium 
Biological research products
for RHBDD1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Rhomboid Domain Containing 11 2     DKFZp547E0521
Rhomboid Domain-Containing Protein 12 3     Rhomboid-Related Protein 42
Rhomboid-Like Protein 42 3     EC 3.4.21.1053
RRP42 3     RHBDL43

External Ids:    HGNC: 230811   Entrez Gene: 842362   Ensembl: ENSG000001444687   UniProtKB: Q8TEB93   

Export aliases for RHBDD1 gene to outside databases

Previous GC identifers: GC02P227409 GC02P219544


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RHBL4_HUMAN, Q8TEB9
Function: Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in
the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane
proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of
endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation
process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of
misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent
manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal
secretion; inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis; modulates
BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity
in spermatogonia




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RHBDD1 gene promoter:
         AP-1   ATF-2   CUTL1   Cdc5   C/EBPalpha   CREB   AREB6   S8   deltaCREB   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRHBDD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for RHBDD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RHBDD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q36.3   Ensembl cytogenetic band:  2q36.3   HGNC cytogenetic band: 2q36.3

RHBDD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RHBDD1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P227700:  view genomic region     (about GC identifiers)

Start:
227,700,297 bp from pter      End:
227,863,931 bp from pter
Size:
163,635 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RHBL4_HUMAN, Q8TEB9 (See protein sequence)
Recommended Name: Rhomboid-related protein 4  
Size: 315 amino acids; 35823 Da
Subunit: Interacts (via C-terminus domain) with VCP. Interacts with ubiquitin and ubiquitinated proteins (By
similarity). Interacts with BIK and STEAP3
Subcellular location: Membrane; Multi-pass membrane protein (Potential). Endoplasmic reticulum membrane; Multi-pass
membrane protein. Mitochondrion (Potential)
Miscellaneous: According to PubMed:22795130; it is not localized in the mitochondrion
Secondary accessions: Q495B9 Q53S43 Q5EBM8 Q6P5V8 Q8IV60 Q9H057
Alternative splicing: 2 isoforms:  Q8TEB9-1   Q8TEB9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RHBDD1: NX_Q8TEB9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TEB9

  • RHBDD1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001161080.1  NP_115652.2  

    ENSEMBL proteins: 
     ENSP00000400765   ENSP00000344779   ENSP00000410384   ENSP00000414801   ENSP00000399694  
     ENSP00000388847   ENSP00000397298   ENSP00000387269   ENSP00000375914  

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    Uscn Proteins for RHBDD1

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0005789endoplasmic reticulum membrane ISS--
    GO:0016021integral to membrane ----
    GO:0030176integral to endoplasmic reticulum membrane ISS--
    GO:0044322endoplasmic reticulum quality control compartment ISS--


    RHBDD1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RHBDD1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR022764 Peptidase_S54_rhomboid_dom

    Graphical View of Domain Structure for InterPro Entry Q8TEB9

    ProtoNet protein and cluster: Q8TEB9

    1 Blocks protein family: IPB002610 Rhomboid-like protein

    UniProtKB/Swiss-Prot: RHBL4_HUMAN, Q8TEB9
    Similarity: Belongs to the peptidase S54 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RHBL4_HUMAN, Q8TEB9
    Function: Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in
    the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane
    proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of
    endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation
    process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of
    misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent
    manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal
    secretion; inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis; modulates
    BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity
    in spermatogonia
    Catalytic activity: Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that
    are contributed by different transmembrane domains
    Enzyme regulation: Inhibited by aprotinin
    Induction: Up-regulated by endoplasmic reticulum stress agents that induce the unfolded protein response (UPR)

    Enzyme Number (IUBMB): EC 3.4.21.1051

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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004175endopeptidase activity IDA--
    GO:0004252serine-type endopeptidase activity IEA--
    GO:0005515protein binding IPI--


    RHBDD1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for RHBDD1:
     Increased G1 DNA content 

    Animal Models:
         Mouse knock-out Rhbdd1tm1.1Mfm for RHBDD1
         1 MGI phenotypic allele for Rhbdd1 (no phenotypes)

    RHBDD1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RHBDD1

    1 Interacting protein for RHBDD1 (Q8TEB93) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SH3GLB2Q9NR463I2D: score=1 
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----
    GO:0006915apoptotic process IEA--
    GO:0010954positive regulation of protein processing ISS--
    GO:0030433ER-associated protein catabolic process ISS--
    GO:0031293membrane protein intracellular domain proteolysis ISS--


    RHBDD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RHBDD1
    Search CenterWatch for drugs/clinical trials and news about RHBDD1 / RHBL4 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RHBDD1 gene (2 alternative transcripts): 
    NM_001167608.1  NM_032276.3  

    Unigene Cluster for RHBDD1:

    Rhomboid domain containing 1
    Hs.471514  [show with all ESTs]
    Unigene Representative Sequence: NM_001167608
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000424132 ENST00000341329(uc002voi.3 uc010fxc.3 uc002voj.3)
    ENST00000437454 ENST00000443477 ENST00000423616 ENST00000448992 ENST00000539613
    ENST00000450679 ENST00000436481 ENST00000409053 ENST00000491490 ENST00000473218
    ENST00000493526 ENST00000483268 ENST00000392062(uc021vxo.1)

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    hsa-miR-29c hsa-miR-29a hsa-miR-374a hsa-miR-520a-5p hsa-miR-3150b-3p hsa-miR-641 hsa-miR-3662 hsa-miR-3163
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    Inhib. RNA
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
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    Additional cDNA sequence: 

    AK026955.1 AK074258.1 AK093986.1 AL512717.1 AL832364.1 AY640233.1 BC015553.1 BC027900.1 
    BC062636.1 BC071679.1 BC089404.1 BC101262.1 BC101263.1 BC101264.1 BC101265.1 BC111056.1 

    11 DOTS entries:

    DT.410318  DT.75100924  DT.65286125  DT.97840670  DT.100772893  DT.100794914  DT.97767190  DT.100794910 
    DT.100772892  DT.100794913  DT.100794917 

    24/129 AceView cDNA sequences (see all 129):

    AA465270 CA427876 BX090911 BM993962 AI139330 AI473203 AA427610 CF243010 
    AA916801 BI834623 AA456392 BQ228178 AA760637 AI076847 CA434330 CD369231 
    AA768899 AI022306 BI836745 BM873582 BX402251 CR594153 BC062636 AI889373 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RHBDD1 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b
    SP1:              -     -     -     -                                                                                                               
    SP2:                                -                                                                                                               
    SP3:                                                                                                                    -                           
    SP4:                                                                                                                                                
    SP5:              -     -     -     -     -                                                                                                         


    ECgene alternative splicing isoforms for RHBDD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RHBDD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RHBDD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RHBDD1

    SOURCE GeneReport for Unigene cluster: Hs.471514

    UniProtKB/Swiss-Prot: RHBL4_HUMAN, Q8TEB9
    Tissue specificity: Expressed strongly in testis

        SABiosciences Custom PCR Arrays for RHBDD1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RHBDD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RHBDD1 gene from 8/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rhbdd11 , 5 rhomboid domain containing 11, 5 81.06(n)1
    80.95(a)1
      1 (42.08 cM)5
    768671  NM_001122685.11  NP_001116157.11 
     823164525 
    chicken
    (Gallus gallus)
    Aves RHBDD11 rhomboid domain containing 1 66.89(n)
    62.95(a)
      424800  XM_422616.3  XP_422616.1 
    lizard
    (Anolis carolinensis)
    Reptilia RHBDD16
    --
    67(a)
    1 ↔ 1
    3(23691193-23701269)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.72352 Transcribed sequences 71.43(n)    AL888635.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1102661 zgc:110266 59.87(n)
    60.19(a)
      550277  NM_001017614.1  NP_001017614.1 
    honey bee
    (Apis mellifera)
    Insecta --
    --
    31(a)
    1 ↔ 1
    GroupUn.4339(12577-13399)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATRBL146
    ATRBL136
    (see all 3)
    RHOMBOID-like protein 13
    (see all 3)
    26(a)
    22(a)
    (see all 3)
    1 ↔ 1
    possible ortholog
    (see all 3)
    3(6024795-6026443)
    3(21991826-21993263)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 3)
    OsRhmbd5 - Putative Rhomboid homologue, expressed
    (see all 3)
    27(a)
    21(a)
    (see all 3)
    1 ↔ 1
    possible ortholog
    (see all 3)
    1(10136191-10139135)
    1(38927559-38929227)


    ENSEMBL Gene Tree for RHBDD1 (if available)
    TreeFam Gene Tree for RHBDD1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RHBDD1 gene

    RHBDD1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RHBDD1
    PGOHUM00000243805


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2544 NCBI SNPs in RHBDD1 are shown (see all 2544    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs168227241,2
    C,F,--227698796(+) ATATTG/TCTTAC 2 -- us2k15Minor allele frequency- N:0.04NA EA 218
    rs107182301,2
    C,--227698798(+) ATTTCT/-TACAT 2 -- us2k11Minor allele frequency- -:0.00NA 2
    rs1928182461,2
    --227699034(+) CTAGGA/GAAATA 2 -- us2k10--------
    rs1852031521,2
    --227699138(+) GGAGGA/CGTATA 2 -- us2k10--------
    rs621910121,2
    C,--227699156(+) TCTAGG/AAAAGA 2 -- us2k13Minor allele frequency- A:0.12NA EA 242
    rs168227261,2
    C,F,--227699161(+) GAAAGA/GGGTAA 2 -- us2k1 tfbs3 trp39Minor allele frequency- G:0.31NA WA CSA EA 505
    rs1384816941,2
    --227699212(+) TTCTTC/TGTCAC 2 -- us2k10--------
    rs1901033731,2
    --227699346(+) TTTAGG/TCAGTT 2 -- us2k10--------
    rs1931209621,2
    --227699397(+) CCAATA/CAACAA 2 -- us2k10--------
    rs1846470141,2
    --227699461(+) GAGCAC/TCTTTA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for RHBDD1 (227700297 - 227863931 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RHBDD1: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RHBDD1 for disorders           About GeneDecksing

    1 disease for RHBDD1:    About MalaCards
    pulmonary function


    Export disorders for RHBDD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RHBDD1 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with RHBDD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis. (PubMed id 22624035)1, 2 Wan C.... Wang L. (2012)
    2. A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis. (PubMed id 18953687)1, 2 Wang Y....Wang L. (2008)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
    7. Ubiquitin-dependent intramembrane rhomboid protease pr omotes ERAD of membrane proteins. (PubMed id 22795130)2 Fleig L....Lemberg M.K. (2012)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)1 Wilk J.B....O'Connor G.T. (2007)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84236 HGNC: 23081 AceView: DKFZp547E052.1 Ensembl:ENSG00000144468 euGenes: HUgn84236
    ECgene: RHBDD1 H-InvDB: RHBDD1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RHBDD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RHBDD1 gene:
    Search GeneIP for patents involving RHBDD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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