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Aliases for RGSL1 Gene

Aliases for RGSL1 Gene

  • Regulator Of G-Protein Signaling Like 1 2 3
  • Regulator Of G-Protein Signaling Like 2 2 3
  • RGSL2 3 4
  • RGSL 3 4
  • Regulator Of G-Protein Signaling Protein-Like 3
  • Regulator Of G-Protein Signalling Like 1 2
  • Regulator Of G-Protein Signalling Like 2 2

External Ids for RGSL1 Gene

Previous Symbols for RGSL1 Gene

  • RGSL2

Summaries for RGSL1 Gene

GeneCards Summary for RGSL1 Gene

RGSL1 (Regulator Of G-Protein Signaling Like 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RGSL1 Gene

Genomics for RGSL1 Gene

Genomic Location for RGSL1 Gene

Start:
182,450,121 bp from pter
End:
182,560,599 bp from pter
Size:
110,479 bases
Orientation:
Plus strand

Genomic View for RGSL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RGSL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RGSL1 Gene

Regulatory Elements for RGSL1 Gene

Proteins for RGSL1 Gene

  • Protein details for RGSL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A5PLK6-RGSL_HUMAN
    Recommended name:
    Regulator of G-protein signaling protein-like
    Protein Accession:
    A5PLK6
    Secondary Accessions:
    • A2A2Z0
    • A6PVM2
    • A6PVM3
    • Q0VAJ4
    • Q0VAJ5
    • Q6ZRL0
    • Q86UV0
    • Q9H084

    Protein attributes for RGSL1 Gene

    Size:
    1076 amino acids
    Molecular mass:
    125688 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for RGSL1 Gene

neXtProt entry for RGSL1 Gene

Proteomics data for RGSL1 Gene at MOPED

Post-translational modifications for RGSL1 Gene

No Post-translational modifications

Other Protein References for RGSL1 Gene

No data available for DME Specific Peptides for RGSL1 Gene

Domains for RGSL1 Gene

Protein Domains for RGSL1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

RGSL_HUMAN
Domain:
  • Contains 1 RGS domain.:
    • A5PLK6
genes like me logo Genes that share domains with RGSL1: view

No data available for Gene Families for RGSL1 Gene

Function for RGSL1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RGSL1 Gene

Localization for RGSL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RGSL1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for RGSL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RGSL1: view

Pathways for RGSL1 Gene

SuperPathways for RGSL1 Gene

No Data Available

Interacting Proteins for RGSL1 Gene

Gene Ontology (GO) - Biological Process for RGSL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway --
GO:0038032 termination of G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with RGSL1: view

No data available for Pathways by source for RGSL1 Gene

Transcripts for RGSL1 Gene

mRNA/cDNA for RGSL1 Gene

Unigene Clusters for RGSL1 Gene

Regulator of G-protein signaling like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RGSL1 Gene

No ASD Table

Relevant External Links for RGSL1 Gene

GeneLoc Exon Structure for
RGSL1
ECgene alternative splicing isoforms for
RGSL1

Expression for RGSL1 Gene

mRNA expression in normal human tissues for RGSL1 Gene

mRNA differential expression in normal tissues according to GTEx for RGSL1 Gene

This gene is overexpressed in Testis (50.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for RGSL1 Gene

SOURCE GeneReport for Unigene cluster for RGSL1 Gene Hs.121200

genes like me logo Genes that share expressions with RGSL1: view

Orthologs for RGSL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RGSL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RGSL1 36
  • 99.35 (n)
  • 98.79 (a)
cow
(Bos Taurus)
Mammalia RGSL1 36
  • 81.82 (n)
  • 74.6 (a)
RGSL1 37
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RGSL1 36
  • 84.13 (n)
  • 76.94 (a)
RGSL1 37
  • 75 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rgsl1 36
  • 77.84 (n)
  • 70.34 (a)
Rgsl1 16
Rgsl1 37
  • 68 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RGSL1 37
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 48 (a)
OneToMany
-- 37
  • 43 (a)
OneToMany
chicken
(Gallus gallus)
Aves LOC100858077 36
  • 52.68 (n)
  • 41.33 (a)
RGSL1 37
  • 36 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RGSL1 37
  • 40 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC565777 36
  • 43.41 (n)
  • 29.51 (a)
Species with no ortholog for RGSL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RGSL1 Gene

ENSEMBL:
Gene Tree for RGSL1 (if available)
TreeFam:
Gene Tree for RGSL1 (if available)

Paralogs for RGSL1 Gene

No data available for Paralogs for RGSL1 Gene

Variants for RGSL1 Gene

Sequence variations from dbSNP and Humsavar for RGSL1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs155552 -- 182,455,850(-) ACCTT(A/G)GGGTA intron-variant
rs166472 -- 182,547,384(-) TCCCC(C/T)ACATC intron-variant
rs169155 -- 182,478,877(+) aaaag(A/G)ctatc intron-variant
rs171961 -- 182,461,395(-) gaaat(C/T)agatt intron-variant
rs171980 -- 182,457,462(-) CAATT(G/T)TAAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RGSL1 Gene

Variant ID Type Subtype PubMed ID
esv259800 OTHER Complex 20981092
esv268729 CNV Insertion 20981092
esv273261 CNV Insertion 20981092
nsv825531 CNV Loss 20364138
nsv825542 CNV Gain 20364138
nsv825553 CNV Gain 20364138
nsv528762 CNV Loss 19592680
esv259830 OTHER Complex 20981092

Relevant External Links for RGSL1 Gene

HapMap Linkage Disequilibrium report
RGSL1

Disorders for RGSL1 Gene

Relevant External Links for RGSL1

Genetic Association Database (GAD)
RGSL1
Human Genome Epidemiology (HuGE) Navigator
RGSL1
genes like me logo Genes that share disorders with RGSL1: view

No data available for UniProtKB/Swiss-Prot for RGSL1 Gene

Publications for RGSL1 Gene

  1. Identification of 9 novel transcripts and two RGSL genes within the hereditary prostate cancer region (HPC1) at 1q25. (PMID: 12801632) Silva A.P. … Camargo A.A. (Gene 2003) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for RGSL1 Gene

Sources for RGSL1 Gene

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